Clinical trials: Inflamed Gums
Gingival Inflammation
Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial
Study Protocol Introduction Title of the research study Comparison Between the effect of Triclosan Toothpaste and chlorhexidine Mouthwash on Gingival Health in Fixed Orthodontic Patients :A randomization controlled clinical…
- Trial name
- NCT07814898
- Testing
- Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash
- Where
- Yemen
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Gingivitis
A Proof-of-principle Clinical Study Investigating the Efficacy of an Experimental Dentifrice Containing Sodium Bicarbonate and Sodium Hyaluronate on Gingivitis
The aim of this study is to develop a daily use toothpaste containing sodium bicarbonate, sodium hyaluronate and sodium fluoride with the intention of providing improved/ fast gum healing.
- Trial name
- NCT04737538
- Testing
- Experimental Dentrifrice, Positive control dentifrice, Negative control dentifrice
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Inflammatory Gingival Enlargement, Gingival Enlargement
Wound Healing After Gingivectomy
Gingival enlargement caused by chronic inflammation may require surgical intervention when non-surgical periodontal therapy is insufficient.
- Conditions
- Chronic Inflammatory Gingival Enlargement, Gingival Enlargement, Gingival Hyperplasia
- Trial name
- OZONE-GING (NCT07517328)
- Testing
- Gaseous ozone application, Gingivectomy/gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ataturk University
Dental Implants, Single-Tooth
The Effect of Different Shapes of Interdental Brushes in the Management of Peri-implant Mucositis and Gingivitis
Rehabilitation of edentulous spaces with dental implants has become a routine treatment option as implants enjoy high survival rates over time.
- Trial name
- NCT03575858
- Testing
- Barrel shaped interdental brush, Tapered interdental brush
- Sponsor
- National University Health System, Singapore
Chronic Gingivitis, Plaque Induced
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral…
- Trial name
- NCT07059572
- Testing
- Group A- 0.15% Guava leaf extract mouthwash group, Group B- 0.2% Chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Gingivitis
Propolis Containing Chewing Gum and Gingivitis
Propolis is a natural, non-toxic, sticky substance produced by honeybees that can kill bacteria, fungi, and larvae invading the beehive. It has been used in the treatment of infections and healing of wounds and burns for years.
- Trial name
- NCT06685419
- Testing
- Propolis containing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- naksaka
Dental Plaque, Gingival Bleeding
Comparison Between Interdental Brush and Water Floss on Plaque Accumulation and Gingival Inflammation in Patients Undergoing Fixed Orthodontic Treatment.
The goal of this clinical trial is to test the ability of water flosser to remove plaque and reduce gingival inflammation in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07240428
- Testing
- Interdental brush, Water floss
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Gingival Bleeding, Von Willebrand Diseases
Gingival Bleeding and Von Willebrand Disease Typ 2 and 3
Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD.
- Trial name
- NCT03078595
- Where
- 2 sites in Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Goethe University
Dental Plaque, Halitosis
Efficacy of Different Toothbrushes and Hygiene Regimen
To evaluate: 1) Evaluate the efficacy of a regimen commercially available versus brush alone on established plaque and gingivitis on adolescents.
- Trial name
- NCT04216069
- Testing
- Total 12 regimen, Toothbrushing alone
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Gingivitis
Efficacy of Oil Pulling Therapy on Supragingival Plaque Growth
Oil pulling is a method based on Ayurvedic medicine which aims to obtain local and systemic benefits by swirling oils in the oral cavity for a period of 15 minutes, before spitting it out.12 Although the exact mechanism of action…
- Trial name
- NCT03962777
- Testing
- chlorhexidine, oil pulling
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Periodontal Diseases
Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis
Plaque-induced gingivitis is a clinical condition that appears to cause persistent inflammation in gingiva. It is a preliminary cause to periodontitis but it can be inverted to address the risk of periodontitis development.
- Trial name
- NCT06904742
- Testing
- Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Gingivitis
Hyaluronic Acid and Gingivitis in Pediatrics
The purpose of this observational, non-controlled, single site trial with a retrospective design is to verify, in a large paediatric population affected by gingivitis, the tolerability and safety of 0.1% HA-based film-forming…
- Trial name
- NCT03003858
- Testing
- 0.1% HA-based film-forming device (Gengigel Prof® Fluid)
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Gingivitis
"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
To study effect of acacia catechu a herbal extract;as antipaque and antigingivitis agent in patients with fixed orthodontic appliances.This study is a double blind randomized controlled trial.
- Trial name
- NCT02154594
- Testing
- Acacia catechu, Chlorhexidine gluconate, Distilled water
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Plaque Induced Gingivitis, Mouth Diseases
Propolis Lozenges Extract and Their Effect on Salivary Biomarkers and on Oral Health Condition in (19_24) Years Old
The goal of this clinical trial is to test the efficiency of using lozenges containing propolis extract over one week to control gingival inflammation and plaque accumulation by measuring the clinical periodontal parameters…
- Conditions
- Plaque Induced Gingivitis, Mouth Diseases, Periodontal Diseases
- Trial name
- NCT06888453
- Testing
- lozenges containing propolis
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Gingivitis, Dental Plaque
A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush
The objective of the study is to evaluate and compare the efficacy of an experimental power brush to a regular manual brush in the reduction of gingivitis and dental plaque over an 8 week period by using the Modified Gingival…
- Trial name
- NCT03624647
- Testing
- Power toothbrush, Manual toothbrush
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontal Diseases, Periodontitis
Validity of a Self-reported Questionnaire for Periodontal Status in a Saudi Population
This observational study will evaluate the accuracy of a self-reported periodontal questionnaire in adults attending screening appointments in Abha, Saudi Arabia.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT07397104
- Testing
- Self-reported periodontal questionnaire and clinical periodontal examination (reference standard)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Apical Periodontitis, Inflammatory Markers
The Efficacy of Two Different Irrigation Methods on PGE2, NO and IL-6 Levels
Today, debates about the effectiveness of Passive Ultrasonic Irrigation (PUI) and Sonically Activated Irrigation (SAI) techniques used to increase the success of endodontic treatment in chronic apical periodontitis (AP) are still…
- Trial name
- NCT06629545
- Testing
- irrigation activation with PUI, irrigation with sonic activation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Gingivitis, Plaque
The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health
The aim of this analysis was to compare the effects of oscillating-rotating (O-R), side-to-side (sonic), and manual toothbrushes on plaque and gingival health after multiple uses.
- Trial name
- NCT04017507
- Testing
- Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,145 people
- Sponsor
- Procter and Gamble
Gingivitis
Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model
This study evaluates the anti-inflammatory effects of Colgate Total® during an experimental gingivitis model developed by Löe et al.
- Trial name
- NCT01799226
- Testing
- Toothpaste without triclosan, Triclosan
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan