Clinical trials: Inflamed Gums
Healthy, Adolescent
GumChucks vs Interdental Brushes in Plaque Removal.
This study compared two ways of cleaning between the teeth, Gumchucks (a new handled dental flossing system) and interdental brushes, in Lebanese adolescents aged 10-15 years.
- Conditions
- Healthy, Adolescent, Dental Plaque, Gingivitis
- Trial name
- NCT07140068
- Testing
- Handled dental flossing system (GumChucks®), Interdental Brush
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Plaque, Dental, Gingivitis
To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.
Triple Blinded Randomized Clinical trial study to assess the efficacy of two brushing regimens: 1) a toothpaste containing stannous fluoride and a standard manual toothbrush as compared to 2) a regular fluoride toothpaste and…
- Trial name
- NCT07605338
- Testing
- Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Rheumatoid Arthritis, Periodontitis
Dental Prophylaxis and Rheumatoid Arthritis
This study evaluates the influence of dental prophylaxis on disease activity of Rheumatoid Arthritis. In addition to standard antirheumatic therapy, recently the question has been raised whether or not there is a supplementary…
- Conditions
- Rheumatoid Arthritis, Periodontitis, Gingivitis, Dental Prophylaxis
- Trial name
- PREPARA II (NCT03087240)
- Testing
- Dental Prophylaxis
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital Heidelberg
Periodontitis, Gingivitis
GFI-1 and Periodontal Disease
Gum disease, including gingivitis and its more advanced form, periodontitis, is a common condition that damages the tissues supporting the teeth.
- Trial name
- NCT07758374
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingivitis, Plaque
A Twelve Week Study of Experimental Mouth Rinses
The purpose of this study is to evaluate the safety and efficacy of experimental mouth rinse formulations compared to a hydroalcohol control mouth rinse and a positive control mouth rinse for the reduction of gingivitis and…
- Trial name
- NCT05120141
- Testing
- Colgate Cavity Protection Toothpaste, American Dental Association (ADA) Ref Toothbrush, Prototype 1 Mouth Rinse
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Gingivitis, Bleeding Gum
Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.
- Trial name
- NCT04438421
- Testing
- Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Periodontitis, Gingivitis
PTPIP51-VAPB Complex in the Periodontal Disease
Gum disease, including gingivitis and more advanced periodontitis, is a common condition that damages the tissues supporting the teeth.
- Trial name
- NCT07705048
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inonu University
Generalized Gingivitis
The Effect of Toothpaste Containing Aloe Vera on Gingivitis
Twenty-four adult patients (male and female) with generalized gingivitis participated in the double-blinded randomized crossover trial was divided into two groups, (aloe vera and Colgate toothpaste).
- Trial name
- NCT04662385
- Testing
- aloe vera toothpaste, Colgate Total
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zainab J Abbas
Gingivitis
Evaluate Inflammation Caused by Gingivitis in Adults
The purpose of this study is to compare the anti-inflammatory efficacy of a dentifrice
- Trial name
- NCT00941668
- Testing
- Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Age Problem
Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults
The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.
- Trial name
- NCT04658225
- Testing
- 0.12% chlorhexidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Gingivitis
Anti-gingivitis Mouthrinse
The purpose of this study is to prove whether a fluoride/zinc lactate containing mouthrinse is able to reduce dental plaque and gingival inflammation in patients who have gingivitis when applied twice daily during brushing at…
- Trial name
- NCT06048627
- Testing
- Amine/zinc lactate/fluoride system, negative control
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontal Diseases, Periodontitis
HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy
This observational clinical study aims to investigate the relationship between the HALP score (Hemoglobin × Albumin × Lymphocyte / Platelet), several blood-based inflammatory indices (including NLR, PLR, LMR, and SII), and…
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis; Chronic
- Trial name
- NCT07312045
- Testing
- Non-surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Okumuş
Gum Inflammation, Periodontal Diseases
Improving Gum Health Among Older Adults Using AI Based mHealth for Personalized OHI
Background: Many older adults in Hong Kong lack thorough tooth cleaning and regular dental check-ups, which can lead to plaque-induced gum diseases and systemic health issues.
- Conditions
- Gum Inflammation, Periodontal Diseases, Oral Hygiene, Oral Health
- Trial name
- NCT07187453
- Testing
- Personalized Oral Hygiene Advice using AI assisted mHealth Tool by Non-Dental Personnel
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gingivitis, Periodontitis
Galectin Role in Periodontal Disease
This study aimed at exploring the effect of nonsurgical periodontal treatment on galectin 1 and 3 GCF levels in patients having gingivitis, periodontitis stage III compared to periodontally healthy individuals and if galectin-1…
- Trial name
- NCT06038812
- Testing
- GCF sample collection, non-surgical periodontal treatment
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Diabetic Nephropathy Type 2, Type 2 Diabetes
Salivary and Serum Inflammatory Biomarkers in Diabetic Nephropathy by Periodontal Status
Chronic inflammation underlies the bidirectional relationship between diabetes and periodontitis, a process that may be further exacerbated in the presence of diabetic nephropathy.
- Conditions
- Diabetic Nephropathy Type 2, Type 2 Diabetes, Periodontitis, Gingivitis
- Trial name
- NCT07498894
- Testing
- clinical periodontal measurements, serum samples, saliva samples
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Pamukkale University
Periodontal Disease, Adverse Pregnancy Outcome
Correlation Between Inflammatory Markers in Gingival Crevicular Fluid, Serum and Amniotic Fluids in Periodontal Pregnant Women
The main causes of adverse pregnancy outcome(s) are reported to be maternal infection and placental, foetal, or uterine pathosis.
- Trial name
- NCT02022865
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Halitosis, Periodontitis
Oral Malodour and Periodontal Disease-related Parameters
The primary aim of the current study was to determine the association between halitosis detection (presence or absence) and periodontal status in non-smoking subjects, and also assess whether halitosis recordings were related to…
- Conditions
- Halitosis, Periodontitis, Gingivitis
- Trial name
- NCT01234948
- Where
- Greece
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Gingivitis
Clinical Study to Assess Therapeutic Delay and Resolution of Induced Gingivitis
Evaluate a stannous technology for its effect on the neutrophil phenotype during an induced gingivitis state.
- Trial name
- NCT05731778
- Testing
- Stannous Fluoride Toothpaste, Colgate fluoride toothpaste
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis: Part 2
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05919134
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Acne Vulgaris, Gingivitis
Association of Acne Vulgaris With Oral Hygiene and Gingivitis
The goal of this observational study is to learn about in the relationship between acne vulgaris and oral hygiene and gingivitis.
- Conditions
- Acne Vulgaris, Gingivitis, Dental Plaque, Oral Hygiene
- Trial name
- NCT06237387
- Testing
- Periodontal examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan University