Clinical trials: Inflamed Gums
Gingivitis
The Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis…
- Trial name
- NCT06211309
- Testing
- co.mouthwas, Kin, Distilled water
- Where
- Iraq
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Toothbrushes
Interactive Power Toothbrush With or Without App vs Manual Toothbrush
It has been suggested that interactive power toothbrushes (PTBs), developed in recent years, provide more successful results in plaque control and effective use of brushing time by enabling patient collaboration and…
- Trial name
- NCT05150132
- Testing
- Oral-B Genius® 8000 power toothbrush with CrossAction brush head with smartphone app(Procter&Gamble,Ohio, USA), Oral-B Genius® 8000 power toothbrush with CrossAction brush head without smartphone app(Procter&Gamble,Ohio, USA), Oral B ClinicLine Pro-FlexSoft (Procter&Gamble,Ohio, USA)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingivitis
Comparing the Inter-dental Brush to Dental Floss
The study's purpose is to find an easy and effective alternative to dental floss for those persons who cannot or choose not to dental floss so that they can maintain and/or achieve optimal oral health.
- Trial name
- NCT00743548
- Testing
- IB = Interdental brush, the intervention, DF = Dental floss, the positive control
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wound Heal, Oral Dryness
Assessing the Efficacy of a Carbamide Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief
The aim of this study is to evaluate the efficacy and safety of a carbamide peroxide mouthwash regarding oral wound healing, postoperative symptoms, xerostomia (dry mouth) and oral hygiene improvement.
- Conditions
- Wound Heal, Oral Dryness, Postoperative Pain, Sjogren's Syndrome
- Trial name
- NCT06363955
- Testing
- Carbamide Peroxide Mouthwash
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens
Periodontal Diseases, Periodontitis
Home Use of Dual-light Photodynamic Therapy for Chronic Periodontitis
This early-stage research is designed to determine the efficacy of the Lumoral method in chronic periodontitis patients. Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long…
- Conditions
- Periodontal Diseases, Periodontitis, Plaque, Dental, Plaque Induced Gingivitis
- Trial name
- NCT05425784
- Testing
- Lumoral treatment, Standard oral hygiene self care
- Where
- 3 sites in Finland
- Volunteers
- 41 people
- Sponsor
- Koite Health Oy
Periodontitis
GCF Levels of IL-1β and IL-6 in Gingivitis and Stage III-Grade C Periodontitis
Periodontal diseases are chronic diseases that occur as a result of a violation of the balance between microbial dental plaque and the host response.
- Trial name
- NCT04689438
- Testing
- gingival crevicular fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Uşak University
Gingivitis, Dental Plaque
Effectiveness of Salvadora Persica Miswak in Improving Plaque Control and Gingival Health
Dental plaque is a main etiologic agent in periodontal disease. Global of Burden Disease Study 2016 ranked periodontal disease as the 11th most prevalent disease affecting 10.5% population worldwide.
- Trial name
- NCT04650685
- Testing
- The novel Salvadora persica toothbrush, The Salvadora persica (miswak) chewing stick, Standard toothbrush and toothpaste (control)
- Where
- Malaysia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Gingivitis, Periodontitis
Determination of the Levels of Lipocalin-2 and Semaphorin3A
The aim of this clinical trial is to investigate the concentrations of Lipocalin-2 and Semaphorin 3A levels in gingival crevicular fluid in subjects with different periodontal diseases.
- Conditions
- Gingivitis, Periodontitis, Periodontal Diseases
- Trial name
- NCT04390997
- Testing
- Non-surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Healthy Subjects With Fixed Orthodontics
The Effect of Probiotic Lactobacillus Reuteri Prodentis Consumption on Gingival Crevicular Fluid Inflammatory Response and Metagenomic Profiles of Oral Microbiome in Orthodontic Patients.
In this study, researchers will test the effectiveness of probiotic consumption against oral pathogenic bacteria and reduce the occurrence of gingival inflammation in subjects using orthodontic fixed appliances (braces).
- Trial name
- NCT04847960
- Testing
- BioGaia Probiotic Lozenges
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Gingivitis
Stannous Fluoride and Gingivitis
8-week study using stannous fluoride toothpaste on subjects with gingivitis ("unhealthy") and without gingivitis ("healthy"). Gingivitis index will be performed at BL, Week 4 and Week 8.
- Trial name
- NCT05326373
- Testing
- Stannous fluoride
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis
Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis
The aim of this study is to evaluate the efficacy of a new interdental cleaning device (Soft-Picks Advanced), as compared to a leading brand floss; and, how ease of use can promote the establishment of a hygienic routine of…
- Trial name
- NCT02883244
- Testing
- Soft-Picks Advanced, Floss
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sunstar Americas
Gingivitis, Gum Disease
Dental Plaque Removal Study
The purpose of this research study is to investigate water flow in dental devices and to understand the function of water flow behind oral hygiene improvements.
- Trial name
- PAU2 (NCT01559987)
- Testing
- Manual Toothbrush only, MTB + Waterpik Ultra Water Flosser 'High', MTB + Floss (MTB+Floss)
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of North Carolina, Chapel Hill
Gingivitis, Plaque
Clinical Study of Toothpaste Containing Zinc Lactate as Compared to Colgate Cavity Protection Toothpaste.
The objective of this six-month clinical research study is to evaluate the clinical efficacy of two dentifrices - Toothpaste containing zinc lactate and Colgate Cavity Protection Toothpaste in reducing gingivitis and dental…
- Trial name
- NCT06563518
- Testing
- Meridol, Colgate Cavity Protection
- Where
- Thailand
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Plaque
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided.
- Trial name
- NCT06244303
- Testing
- manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Dental Plaque
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes
- Trial name
- NCT05594004
- Testing
- Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,929 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontal Disease
Evaluation and Comparison of the Efficacy of Triphala Mouthwash and 0.2% Chlorhexidine
The purpose of this study is to evaluate the usefulness of triphala mouthwash in comparison with the gold standard chlorhexidine in hospitalized and periodontally diseased patients.
- Trial name
- NCT01900535
- Volunteers
- 120 people
- Sponsor
- Tatyasaheb Kore Dental College
Gingivitis
Plaque Inhibitory Effect of Neutral Electrolysed Water in the Form of a Mouthwash in a 4-day Non-brushing Model
Electrolysed water (EOW) is produced by the electrolysis of sodium chloride in an aqueous solution, producing chlorine gas at the anode and sodium hydroxide and hydrogen at the cathode.
- Trial name
- NCT05709015
- Testing
- Neutral electrolyzed water, Chlorhexidine digluconate
- Where
- Slovenia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Oral Health
Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children.
Purpose: This cluster randomized controlled trials study aims to investigate whether different number of topics delivered through educational video affect the oral health status, knowledge, attitude and practice of preschool…
- Trial name
- NCT06073392
- Testing
- Educational video
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Plaque-Induced Gingivitis
Pain Perception After Manual and Ultrasonic Periodontal Debridement in Patients With Gingivitis
This study compared immediate pain perception following manual and ultrasonic supragingival periodontal debridement in patients with plaque-induced gingivitis.
- Trial name
- NCT07847736
- Testing
- Manual Supragingival Debridement, Ultrasonic Supragingival Debridement
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people
- Sponsor
- Recep Tayyip Erdogan University
Tooth Abrasion, Gingival Recessions
The Effect of Retraction Cord on the Surrounding Periodontal Tissues in Restorative Treatment
The goal of this clinical trial is to learn whether a retraction cord affects gum health when used during tooth restoration procedures.
- Conditions
- Tooth Abrasion, Gingival Recessions, Non-Carious Cervical Lesions (NCCLs), Periodontal Health
- Trial name
- NCT07734935
- Testing
- Gingival Retraction Cord, Composite Resin Restorative, Universal Adhesive - G-Premio Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Istanbul University