Clinical trials: Inflammation, Brain
Alcohol Use Disorder
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
The goal of this clinical trial is to identify sex-specific biomarkers that confer greater susceptibility for Alcohol Use Disorder (AUD) and differentiate how treatment response varies by sex in people with Alcohol Use Disorder.
- Trial name
- ABSTAIN (NCT06426303)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milky Kohno
Multiple Sclerosis
Natalizumab and Chronic Inflammation
In this study the investigators will assess the ability of Natalizumab, a medication given to treat multiple sclerosis (MS), to restore blood brain barrier integrity and repair subtle leakages of the blood brain barrier (BBB).
- Trial name
- NCT05177718
- Testing
- Natalizumab 300 MG in 15 ML Injection
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vanderbilt University Medical Center
Ovarian Dermoid Cyst
Paraneoplastic Neurologic Encephalitis and Mature Cystic Teratoma
Ovarian dermoid cyst, also known as benign mature teratoma, originate from germ cells in the ovary, and is the most common benign ovarian tumor (44-70%).
- Trial name
- dermoid_cyst (NCT05223543)
- Testing
- Blood sample
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Functional Dyspepsia, Epigastric Pain Syndrome
Cognitive Behavioral Therapy for Functional Dyspepsia (Epigastric Pain Syndrome and Postprandial Distress Syndrome Subtypes)
The goal of this clinical trial is to learn whether adding Cognitive Behavioral Therapy (CBT) to standard medical treatment can improve symptoms in adults with Functional Dyspepsia.
- Conditions
- Functional Dyspepsia, Epigastric Pain Syndrome, Postprandial Distress Syndrome
- Trial name
- FD-CBT (NCT07577089)
- Testing
- Optimized Standard Treatment (OPT), Cognitive Behavioral Therapy + Optimized Standard Treatment (CBT + OPT)
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Alzheimer Disease, Mild Cognitive Impairment
A Study of NTRX-07 in Participants With Alzheimer's Disease
1. Study Overview NeuroTherapia Inc. is conducting a clinical study to explore the safety and effects of a new drug called NTRX- 07.
- Trial name
- SPPN-AD (NCT07058688)
- Testing
- NTRX-07
- Where
- 6 sites in Czechia, Hungary and 1 more
- Volunteers
- 48 people
- Sponsor
- NeuroTherapia, Inc.