Clinical trials: Inflammation Chronic
Sinus; Empyema, Maxillary (Chronic)
The Osteogenic Potential of Human Maxillary Sinus Shneiderian Membrane
The objectives of this study are : 1. to test the the osteogenic potential of human maxillary sinus schneiderian membrane (hMSSM). 2.
- Trial name
- HMSSM (NCT02676921)
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BERBERI ANTOINE
Recurrent Acute Pancreatitis, Chronic Pancreatitis
Soy Tomato Juice to Improve Outcomes in Pancreatitis
This goal of this clinical trial is to see if people with recurrent acute pancreatitis or chronic pancreatitis can tolerate and regularly drink a tomato juice beverage.
- Trial name
- STOP (NCT07447687)
- Testing
- Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University
Chronic Hepatitis b, Viremia
Adaptability of an Undetectable = Untransmissible Model for HBV
Persons with chronic hepatitis B (HBV) infection and active viremia are infectious and may transmit virus to others through blood/body fluid exposure.
- Trial name
- NCT07449091
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acute Aortic Dissection, Surgery (Cardiac)
Immune-Inflammatory Markers in Aortic Dissection
Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for…
- Conditions
- Acute Aortic Dissection, Surgery (Cardiac), Systemic Immune-inflammation Index, Postoperative Death
- Trial name
- NCT07683260
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Bursa City Hospital
Chronic Pelvic Pain
The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation
A prospective random control clinical trials to research Fuke Qianjin capsule's effects on ameliorating the pain caused by chronic pelvic disease.
- Trial name
- NCT03251560
- Testing
- Fuke Qianjin capsule
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Aijun Sun
Coronary Artery Diseases
BIOFLOW-III VIP Russia Registry Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). Along with it, an explanatory (hypothesis-finding) problem will be investigated, whether the patient's body…
- Trial name
- NCT02247492
- Where
- 7 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Biotronik Russia
Contraception
Synthetic vs Natural Estrogen in Combined Oral Contraception
The main objective of the study is to compare the metabolic effects of natural estradiol and synthetic ethinylestradiol used in combined oral contraception in healthy women.
- Trial name
- SYLVI (NCT02352090)
- Testing
- Ethinyl estradiol / dienogest, Estradiol valerate / dienogest, Dienogest
- Where
- 2 sites in Finland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Infertility, Assisted Reproductive Technology Outcomes
The Impact of Having a Tattoo on Fertility Treatment Outcome
Tattoos are increasingly common among women of reproductive age, yet their potential systemic inflammatory effects and impact on fertility treatment outcomes are unknown.
- Trial name
- NCT07405879
- Where
- Canada
- Volunteers
- 328 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
End Stage Renal Disease, Haemodialysis
The Effect of Combining Medium Cut Off Dialysis Membrane and Diet Modification on Reducing of Inflammation Response
The investigators purpose is to research the impact of the simultaneous use of a new dialysis membrane with higher permeability for medium and protein bound uraemic toxins (medium cut-off dialysis membrane Theranova®) combined…
- Conditions
- End Stage Renal Disease, Haemodialysis, Diet, Healthy, Chronic Inflammation
- Trial name
- NCT04260412
- Testing
- medium cut-off (MCO) dialysis membrane, Dietary fiber mixture (Plantago Psyllium 69% and Inulin 30%), Sodium propionate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Cerebral Palsy, Cerebral Palsy, Mixed
10-week Leucine Supplementation in Cerebral Palsy
The purpose of this study is to assess the effects of 10-weeks leucine supplementation on muscle growth, metabolism, body composition, inflammation and wellbeing in adolescents and young adults with CP.
- Conditions
- Cerebral Palsy, Cerebral Palsy, Mixed, Cerebral Palsy Ataxic
- Trial name
- NCT03668548
- Testing
- Leucine
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- St Mary's University College
Asthma, Aspirin-Induced, Chronic Rhinosinusitis With Nasal Polyps
Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab)
Primary objective: to investigate the efficacy of Mepolizumab 100 milligram (mg) every month compared to placebo in reducing validated Sinonasal Outcome Test -22 score and on reducing endoscopic Nasal Polyp Score.
- Trial name
- AirGOs-biol (NCT04823585)
- Testing
- Mepolizumab
- Where
- Finland
- Volunteers
- 95 people
- Sponsor
- Helsinki University Central Hospital
Chronic Kidney Disease, Secondary Hyperparathyroidism
Effects of Vitamin D on Renal Blood Flow, Proteinuria and Inflammation in Patients With Chronic Kidney Disease
Active forms of vitamin D and its analogs are used to treat elevated parathyroid hormone levels and bone disease in chronic kidney disease (CKD).
- Trial name
- NCT01426724
- Testing
- Contrast Enhanced Ultrasonography
- Where
- United States
- Sponsor
- University of Virginia
Myositis
Physical Exercise as a Targeted Therapy in Patients With Chronic Rheumatic Muscle Inflammation
The objectives of this study are to test if hypoxia in muscle tissue is an important factor contributing to clinical symptoms in chronic rheumatic muscle inflammation and to evaluate if a 12 week endurance exercise program will…
- Trial name
- NCT01184625
- Testing
- Physical Exercise
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Inflammation
Effect of Chronic Consumption of a Cranberry Beverage on Inflammation and Oxidative Stress
The objective of this randomized, double-blind, placebo-controlled, parallel-design clinical trial is to investigate the potential antioxidant benefits of a cranberry beverage.
- Trial name
- NCT01527617
- Testing
- Cranberry, Non-Cranberry beverage
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Tufts University
Chronic Inflammation, Inflammaging
2021 PMT iAge® Intervention Trial by Edifice Health
This is a decentralized, double-blind, randomized, placebo-controlled study to assess the effectiveness of different dietary supplements in decreasing systemic chronic inflammation (SCI) and lowering inflammatory age (iAge®).
- Trial name
- NCT04983017
- Testing
- Dietary supplement
- Where
- 2 sites in United States
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Edifice Health
COPD, COPD (Chronic Obstructive Pulmonary Disease)
Probiotics in COPD: Effects on Symptoms, Lung Function, and Inflammation
The goal of this randomized, placebo controlled, double-blind clinical trial is to find out whether a probiotic supplement can help adults with chronic obstructive pulmonary disease (COPD) breathe better and better control their…
- Conditions
- COPD, COPD (Chronic Obstructive Pulmonary Disease), Probiotic, Probiotic Supplement
- Trial name
- NCT07339280
- Testing
- Probiotic Capsule
- Where
- 5 sites in Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Psoriasis Vulgaris
Clinical Study to Investigate Psorax35 Supplementation in Patients With Psoriasis
The main objective of this study is to establish the efficacy and safety of Psorax35 supplementation in patients with mild to moderate Psoriasis.
- Trial name
- NCT03359577
- Testing
- Psorax35, MCT oil
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Arctic Nutrition AS
Osteoporosis
1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids
This 1-year open-label extension to CZOL446H2337 is designed to evaluate the safety and efficacy of zoledronic acid twice yearly in osteoporotic children treated with glucocorticoids.
- Trial name
- NCT01197300
- Testing
- Zoledronic acid
- Where
- 10 sites in Australia, Canada and 4 more
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Septic Shock
Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock
Retrospective study to examine the effects of chronic antihypertensive medications on vasopressor dosing in septic shock
- Trial name
- NCT02884011
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- Rush University Medical Center