Clinical trials: Inflammation Chronic
Exercise Recovery, Exercise-induced Muscle Damage
Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes
Athletes frequently perform high-intensity exercise to improve physical performance and aerobic capacity. However, such training can induce exercise-induced muscle damage, oxidative stress, and inflammatory responses that may…
- Conditions
- Exercise Recovery, Exercise-induced Muscle Damage, Oxidative Stress, Sports Performance
- Trial name
- CORD-RECOV (NCT07664345)
- Testing
- Pre-Exercise Cordyceps Sinensis, Post-Exercise Cordyceps Sinensis
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Obesity, Chronic Inflammation
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)
Omega-3 fatty acids, especially EPA and DHA have long been acknowledged for their capacity to counteract inflammatory responses in the human body.
- Trial name
- EPICO (NCT05068557)
- Testing
- Dietary plan along with fish oil capsules (3 capsules daily. Containing EPA+DHA: 1.8 g)., Dietary plan along with chia/linseed oil capsules (3 capsules daily. Containing ALA 1.6 g).
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Acute and Chronic Gastric Inflammation Patients
Phase 2a Study to Evaluate Optimum Dosage and Stability of DW-3101 in Gastric Inflammation Patients
The purpose of this study is to find optimum dosage of DW-3101 by evaluating efficacy and safety of each dosage group in Korean patients with acute and chronic gastric inflammation.
- Trial name
- NCT02386007
- Testing
- DW-3101_150mg, DW-3101_300mg, DW-3101_600mg
- Volunteers
- 60 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Kidney Disease
Effects of High Dietary Fiber Supplementation in Diabetic Chronic Kidney Disease
Loss of kidney function results in accumulation in the blood of molecules that are either excreted or metabolized by the kidney. Collectively, these molecules are termed Uremic Retention Molecules (URMs) or toxins.
- Trial name
- NCT01838330
- Testing
- psyllium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Sclerosis, Multiple, Neurocognitive Impairment, Mild
The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders
The goal of this clinical trial is to test a new digital therapeutic solution which combines a holistic, multidimensional rehabilitation program based on dance and music with an innovative motivational system (DANCEREX-DTx) in…
- Conditions
- Sclerosis, Multiple, Neurocognitive Impairment, Mild, Neurocognitive Dysfunction
- Trial name
- DANCEREX-DTx (NCT06112639)
- Testing
- DANCEREX-DTx, Multidimensional dance-based program, Educational Program
- Where
- 3 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Insomnia, Nonorganic, Chronic Insomnia Disorder
Individualized TCM Pattern-Based Thread-Embedding Acupuncture Plus Auricular Acupressure for Chronic Insomnia
Chronic insomnia disorder is a common sleep disorder associated with impaired daytime functioning and may be accompanied by alterations in immune-inflammatory and gut-related biological processes.
- Trial name
- NCT07552714
- Testing
- Thread embedding acupuncture, Auricular acupressure
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Trauma Injury, Trauma
The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery.
- Conditions
- Trauma Injury, Trauma, Critical Illness, Microbiome
- Trial name
- NCT06606119
- Testing
- Data and tissue collection
- Where
- 3 sites in United States
- Volunteers
- 275 people
- Sponsor
- University of Florida
Sinus; Empyema, Maxillary (Chronic)
The Osteogenic Potential of Human Maxillary Sinus Shneiderian Membrane
The objectives of this study are : 1. to test the the osteogenic potential of human maxillary sinus schneiderian membrane (hMSSM). 2.
- Trial name
- HMSSM (NCT02676921)
- Where
- Lebanon
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BERBERI ANTOINE
Cardiovascular Disease, Inflammation
Effect of a Spice Blend on Cardiovascular Risk Factors and Diet Satisfaction
This study is a randomized 3-period crossover, controlled feeding study designed to evaluate the effects of the most commonly consumed spices in the U.S.
- Trial name
- NCT03064932
- Testing
- Controlled feeding diet
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Penn State University
Chronic Kidney Diseases
Effects of Curcumin in Patients in Chronic Kidney Disease
Many studies have been conducted to identify therapeutic strategies to modulate inflammation and oxidative stress, complications that contribute to the increased morbidity and cardiovascular mortality in patients with chronic…
- Trial name
- NCT03475017
- Testing
- Active Comparator: Supplement A
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Denise Mafra
COPD
COPD, Inflammation and Rehabilitation
Patients with chronic obstructive pulmonary disease, also known as COPD or emphysema, is like any other with a chronic illness not only affected by the physical discomfort the illness gives.
- Trial name
- NCT01700296
- Testing
- Best care
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Odense University Hospital
Chronic Obstructive Pulmonary Disease
Airway Inflammation, Symptoms and Lung Function in COPD
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease with high prevalence worldwide and with relevant impact on patient-related quality of life, morbidity and mortality.
- Trial name
- NCT01216592
- Testing
- COPD treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università degli Studi di Ferrara
Ocular Inflammation
Triamcinolone Versus Topical Treatment in Post Operative Phacoemulsification
Cataract extraction is one of the most common operative procedures performed throughout the world. Conventionally, patients are discharged with postoperative drops of steroids and antibiotics or a combination of both.
- Trial name
- NCT00789971
- Testing
- triamcinolone acetonide, Maxitriol
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- Sligo General Hospital
COPD
Does Extra-fine Hydrofluoroalkane-beclomethasone Dipropionate (HFA-BDP) Suppress Small Airways Inflammation in Chronic Obstructive Pulmonary Disease (COPD)?
Chronic obstructive pulmonary disease or 'COPD' is a chronic disease, which means that it cannot be cured, but that inhalers and tablets can be used to control the symptoms.
- Trial name
- NCT00921921
- Testing
- HFA-BDP
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Dundee
Type 2 Diabetes, Chronic Inflammation
Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)
This study plans to learn more about the effect of semaglutide once weekly on intestinal permeability in individuals with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Chronic Inflammation, Intestinal Permeability
- Trial name
- SIB (NCT04979130)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Colorado, Denver
Sickle Cell Disease
Cannabinoids for the Reduction of Inflammation and Sickle Cell Related Pain
A randomized, double blind, study of dronabinol as a palliative agent in the treatment of pain, inflammation, and other complications of sickle cell disease (SCD).
- Trial name
- CRISP (NCT05519111)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Kidney Diseases, Cachexia
CKD Cachexia and Gut Microbiome
Cachexia is common in patients with chronic kidney disease (CKD) and is associated with increased morbidity and mortality. Cachexia is a complex syndrome, in which inflammation and retention of uremic toxins are two main…
- Trial name
- DYNAMICA (NCT06986265)
- Testing
- Collection of clinical data and biological sampling
- Where
- 2 sites in Belgium
- Volunteers
- 157 people
- Sponsor
- Université Catholique de Louvain
Anemia, Chronic Diseases
First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NOX-H94
This is the first clinical trial with NOX-H94. The purpose of this clinical trial is to identify a safe and efficacious treatment regimen for the clinical development of NOX-H94 in patients with anemia of chronic disease…
- Conditions
- Anemia, Chronic Diseases, Inflammation
- Trial name
- NCT01372137
- Testing
- NOX-H94, Glucose 5%
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TME Pharma AG
End-Stage Renal Disease
The Effect of Nighttime Dialysis on the Inflammation of Kidney Failure
This study will determine whether a new form of home hemodialysis carried out at night during sleep reduces blood levels of hormone-like substances called cytokines that may cause fatigue and increase blood fats and sugar.
- Trial name
- NCT00234130
- Testing
- nocturnal vs conventional dialysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rockefeller University
Chronic Obstructive Pulmonary Disease, Acute Respiratory Failure
Protocol Chronic Obstructive Pulmonary Disease
The main objective of the study is to evaluate the predictive factors of the endothelial function to the waning of an acute exacerbation in COPD.
- Trial name
- NCT00404430
- Where
- France
- Volunteers
- 121 people
- Sponsor
- University Hospital, Grenoble