Clinical trials: Inflammation Chronic
Obesity & Overweight, Normal Weight Adults
Long-term Iron Absorption and Loss in Women
Obese people typically have chronic low-grade inflammation. Based on short-term studies, this inflammation could affect the absorption, utilization, storage, and mobilization of iron, and individuals with inflammation might…
- Trial name
- NCT07855939
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Overweight, Obesity
Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk
The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity.
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Healthy
- Trial name
- PINEAPPL (NCT06355544)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Integrative Phenomics
Chronic Kidney Disease, Inflammation
Anti-Inflammatory Effects of Rosiglitazone in Patients With Stage 4 and 5 Chronic Kidney Disease
The purpose of this study in patients with stage 4 and 5 chronic kidney disease is to determine whether rosiglitazone can reduce inflammatory markers and to investigate its effect on intima media thickness, calcification and…
- Trial name
- Hercules (NCT00169923)
- Testing
- rosiglitazone
- Where
- 2 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Leiden University Medical Center
Kidney Disease, Oxidative Stress
Red Propolis Supplementation as a Strategy in Chronic Kidney Disease
The objective of this study is to evaluate the effects of red propolis on inflammation and oxidative stress in patients with chronic kidney disease on conservative management.
- Conditions
- Kidney Disease, Oxidative Stress, Chronic Kidney Disease, Inflammation
- Trial name
- NCT07597005
- Testing
- Red Propolis
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal Fluminense
Type 2 Diabetes, Chronic Inflammation
Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)
This study plans to learn more about the effect of semaglutide once weekly on intestinal permeability in individuals with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Chronic Inflammation, Intestinal Permeability
- Trial name
- SIB (NCT04979130)
- Testing
- Semaglutide
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Colorado, Denver
COPD (Chronic Obstructive Pulmonary Disease)
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate - severe chronic obstructive pulmonary disease (COPD).
- Trial name
- Sirius (NCT07646587)
- Testing
- WIN378
- Where
- 32 sites in United States, Argentina
- Volunteers
- 105 people
- Sponsor
- Windward Bio
Sarcopenia, Chronic Kidney Disease
Egg Albumin and Agave Fructans With Exercise in Hemodialysis
Patients receiving maintenance hemodialysis frequently develop loss of muscle mass, reduced physical function, and chronic inflammation.
- Conditions
- Sarcopenia, Chronic Kidney Disease, Hemodialysis
- Trial name
- EAF-HD (NCT07877545)
- Testing
- HemProt, Functional Exercise Program
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Centenario Hospital Miguel Hidalgo
Bronchiolitis Obliterans
Lung Function, LCI, Bronchial Inflammation and Epigenetics of Patients With BO
Bronchiolitis obliterans is a chronic disease in which a persistent inflammatory process leads to obliteration of the small airways.
- Trial name
- FRABO-03 (NCT02627833)
- Testing
- observation
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
COPD
A Placebo-controlled Trial of Daliresp on Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to propose that roflumilast is associated with meaningful reductions in biomarkers of pulmonary inflammation and sputum neutrophilia, including confirmation of previously described results, and…
- Trial name
- NCT01572948
- Testing
- roflumilast
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Alabama at Birmingham
Recurrent Acute Pancreatitis, Chronic Pancreatitis
Soy Tomato Juice to Improve Outcomes in Pancreatitis
This goal of this clinical trial is to see if people with recurrent acute pancreatitis or chronic pancreatitis can tolerate and regularly drink a tomato juice beverage.
- Trial name
- STOP (NCT07447687)
- Testing
- Soy-tomato juice product, Will include a soy-tomato juice product to be consumed during the 4 week intervention phase. A total of about 12 ounces (administered in two small cans) of the juice will be consumed
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Ohio State University
Heart Failure
A Pilot Study of Probiotic Saccharomyces Boulardii Use in Chronic Heart Failure Patients. Estudo PROICA
The purpose of this study is to evaluate the feasibility, safety and effects in inflammatory response of the therapy with a probiotic agent, the yeast Saccharomyces boulardii (SB), in chronic heart failure patients.
- Trial name
- PROICA (NCT01500343)
- Testing
- Saccharomyces boulardii
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal Fluminense
Inflammation, Skin Abnormalities
Effects of Bend Beauty's Anti-Aging Formula on Inflammatory Markers
This is a phase IV, randomized, double-blind, placebo-controlled, three-arm, parallel intervention study including three groups of 25 subjects between 35-65 years of age, treated with either Bend Beauty's Anti-Aging Formula, fish…
- Conditions
- Inflammation, Skin Abnormalities, Skin Pigment, Inflammatory Response
- Trial name
- BENCHMARK (NCT03862872)
- Testing
- Anti-Aging Formula, Control Fish Oil
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bend Beauty Inc.
Chronic Kidney Failure, Frailty
Systemic Activation of Inflammasomes and Frailty in Older Candidates to Kidney Transplantation
Kidney transplantation (KT) benefit-risk ratio assessment is a challenge in a growing population of older patients with end-stage kidney disease.
- Conditions
- Chronic Kidney Failure, Frailty, Aging, Inflammation
- Trial name
- INTRA (NCT06887075)
- Testing
- Blood sample, Geriatric assessment standardized
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Acute Leukemia, Chronic Leukemia
Fungemia in Hematologic Malignancies
The purpose of this study is to determine the risk factors for fungemia in a population of patients diagnosed with hematologic malignancies and eligible for chemotherapy.
- Conditions
- Acute Leukemia, Chronic Leukemia, Multiple Myeloma, Lymphoma
- Trial name
- NCT02451592
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne
Iron-Deficiency Anemia, Inflammation
Ferumoxytol for Iron-Deficiency Anemia in Chronic Kidney Disease and Peritoneal Dialysis Patients
The purpose of this study is to investigate the efficacy of ferumoxytol for the repletion of iron stores and correction of iron deficiency anaemia in patients with severe chronic kidney disease or end-stage chronic kidney disease…
- Conditions
- Iron-Deficiency Anemia, Inflammation, Oxidative Stress
- Trial name
- NCT01942460
- Testing
- Ferumoxytol
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Georges Ouellet
Chronic Renal Disease, Iron-Deficiency Anemia
Oral Iron Supplementation for Patients With Chronic Kidney Disease
The hypothesis of this research is that oral iron prescribed in a single dose in alternate day could mitigate the side effects with regard to intestinal microbiota, inflammation, oxidative stress and improve the hematological…
- Conditions
- Chronic Renal Disease, Iron-Deficiency Anemia, Anemia of Chronic Kidney Disease, Dysbiosis
- Trial name
- NCT05544513
- Testing
- Ferrous sulfate 3 days week, Ferrous sulfate daily, Ferrous sulfate higher concentration
- Where
- Brazil
- Volunteers
- 6 people
- Sponsor
- Universidade Federal Fluminense
COPD Exacerbation, Periodontal Health
Efficacy of Periodontal Treatment on Systemic Inflammation and for Prevention of Exacerbations in Patients With COPD
Current data are showing a potential link between inflammatory biomarkers in chronic periodontitis and COPD. However the impact of periodontal treatment on systemic inflammation as measured by biomarkers and time to occurrence of…
- Trial name
- Expertention (NCT03279718)
- Testing
- Periodontal Treatment
- Where
- 3 sites in Germany
- Volunteers
- 4 people
- Sponsor
- Heidelberg University
Chronic Lower Respiratory Diseases
Evaluation of the Safety and Clinical Efficacy of NRICM102 in Patients With Chronic Lower Respiratory Tract Diseases
This study is to assess safety and efficacy of NRICM102 decoction in participants with CLRD. This study will be conducted in 70 participants.
- Trial name
- NCT06690203
- Testing
- NRICM102
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Taichung Veterans General Hospital
Renal Failure Chronic Requiring Hemodialysis, Hepatitis C
Prohepcidin, Inflammation and Iron Homeostasis in Hemodialysis Patients With Chronic Hepatitis C
The aim of this study is to address questions regarding the link among hepcidin, hematological iron markers, inflammation and hepatitis C in HD patients.
- Trial name
- NCT01272479
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University