Clinical trials: Inflammation Chronic
Prostatitis
A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis
The purpose of this study is to compare the safety and effectiveness of levofloxacin to ciprofloxacin in patients with chronic bacterial prostatitis.
- Trial name
- NCT00236808
- Testing
- levofloxacin
- Volunteers
- 383 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension
Patients with cirrhosis patients have a high incidence of sepsis which can trigger decompensation and may result in prolonged hospital stay and increased mortality.
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Shock, Septic, Shock Hypovolemic
- Trial name
- NCT05441878
- Testing
- 20% albumin, Balanced salt solution
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cigarette Smoking
Development of Biomarkers of Effect From Chronic Tobacco Usage
This study was conducted to develop biomarkers of tobacco effect that would indicate potential harm related to tobacco consumption.
- Trial name
- NCT01923402
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- R.J. Reynolds Tobacco Company
Chronic Kidney Diseases, Chronic Kidney Disease stage3
Effects of Brazil Nut Supplementation in Patients With Chronic Kidney Disease Undergoing Conservative Treatment
The aim of this study is to evaluate the effects of Brazil nut supplementation on inflammation, oxidative stress and intestinal microbiota in patients with chronic kidney disease undergoing conservative treatment.
- Conditions
- Chronic Kidney Diseases, Chronic Kidney Disease stage3, Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B
- Trial name
- NCT06394544
- Testing
- Brazil Nut
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal Fluminense
End Stage Renal Disease, Inflammation
Evaluation of Biocompatibility and Performances of 4 Dialyzers in Different Mode Treatments
Prospective multicenter randomized cross-over study Number of patients : 32 (8 patients per group) Obtain objectives data to advise each hemodialyzer according to dialysis treatment and patient profile.
- Trial name
- BIOMODAL (NCT03262272)
- Testing
- VIE A Hemodialyzer, Rexsys 27H hemodialyzer, Leoceed 21HX hemodialyzer
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Hemotech
Pulmonary Disease, Chronic Obstructive (COPD), Pulmonary Diseases
Effect of Dietary Fiber Supplementation on Systemic Inflammation and Clinical Parameters in COPD
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent respiratory symptoms and systemic inflammation. Dietary fiber intake has been associated with beneficial effects on gut microbiota composition and…
- Conditions
- Pulmonary Disease, Chronic Obstructive (COPD), Pulmonary Diseases, Pulmonary Diseases, Obstructive
- Trial name
- NCT07868211
- Testing
- Dietary Fiber Supplementation
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Júnea Regina Pires Drews
COPD, OSA
The Effect of Exercise on Systemic Inflammation in Veterans With COPD and OSA
The overlap syndrome (OS), i.e. the association of both Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) in a single Veteran, is prevalent and associated with increased cardiovascular disease (CVD)…
- Conditions
- COPD, OSA, Home Exercise, Inflammation
- Trial name
- NCT03431103
- Testing
- Exercise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Salem Veterans Affairs Medical Center
Oxidative Stress, Inflammation
CoQ10 Biomarker Trial
The investigators believe that relieving the oxidative stress experienced by hemodialysis patients may help improve cardiovascular health.
- Conditions
- Oxidative Stress, Inflammation, Endothelial Dysfunction
- Trial name
- NCT01408680
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Washington
Chronic Periodontitis
Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin
Periodontitis is an inflammatory/infectious disease of high prevalence in the population and which has been linked to several chronic inflammatory systemic diseases.
- Trial name
- NCT02641210
- Testing
- Periodontal Treatment, Albendazole
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Federal University of Maranhao
Acute-On-Chronic Liver Failure, Sepsis
Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis
This study aims to evaluate the efficacy and safety of the double plasma cytokine adsorption system with sequential low-dose plasma exchange (DPCAS+LPE) in patients with acute-on-chronic liver failure (ACLF) complicated by…
- Trial name
- NCT06562803
- Testing
- double plasma cytokine adsorption system with sequential low-dose plasma exchange, plasma exchange
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Heart Failure, Congestive, Renal Failure Acute Chronic
Effect of a Focused Point-of-care Ultrasonography Screening Protocol in Hospitalized Patients
This research project aims to establish a real-time focused ultrasound examination protocol for routine assessment of hospitalized patients, including evaluations of the inferior vena cava (IVC), pericardial effusion…
- Conditions
- Heart Failure, Congestive, Renal Failure Acute Chronic, Liver Cirrhosis, Sepsis
- Trial name
- NCT07656428
- Where
- Taiwan
- Volunteers
- 9,000 people
- Sponsor
- National Taiwan University Hospital
Heart Failure, Heart Failure Preserved Ejection Fraction
Exercise, Mediterranean Diet and Inflammation in Heart Failure
This randomized clinical trial will test whether a multimodal anti-inflammatory program added to standard treatment improves the prognosis of patients with heart failure who have recently been hospitalized or visited the…
- Conditions
- Heart Failure, Heart Failure Preserved Ejection Fraction, Heart Failure, Diastolic (HFpEF), Chronic Inflammation
- Trial name
- FLARE-HF (NCT07885514)
- Testing
- Structured exercise training program, Mediterranean diet counseling, Standard heart failure management
- Volunteers
- 214 people
- Sponsor
- Hospital Severo Ochoa
Stroke, Insulin Resistance
Trial of Aerobic Exercise Training in Stroke Survivors
The purpose of this study is to examine the effects of treadmill training on inflammation in the skeletal muscle and adipose tissue, insulin action in the skeletal muscle, and whole body glucose metabolism in stroke survivors.
- Conditions
- Stroke, Insulin Resistance, Sedentary Lifestyle
- Trial name
- NCT00891514
- Testing
- Aerobic Exercise, Stretching
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Baltimore VA Medical Center
COPD, Inflammation
A Multi-Center Study of Rehabilitation to Stable Chronic Obstructive Pulmonary Disease (COPD) Patients
This is a multi-center prospective follow-up study. to choose the stable COPD patients in community to compare different modes of exercise (cycling and walking) to compare the effect of different exercises on the quality of…
- Trial name
- NCT00686660
- Testing
- cycling, walking, cycling, non-walking, walking, walking
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease
Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD
This study will examine the inflammatory response to exercise encompassed as part of a standard pulmonary rehabilitation programme in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- CIMPRES-COPD (NCT02740686)
- Testing
- Sample collection
- Where
- 6 sites in United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Chronic Obstructive Pulmonary Disease
Systemic Inflammation in Chronic Obstructive Pulmonary Disease (COPD)
COPD is ranked number 3 by the WHO list of important diseases worldwide and is the only disease with increasing mortality. The pathogenesis of cigarette smoke-induced COPD is obscure, therefore more insight is needed to design…
- Trial name
- NCT00850863
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Top Institute Pharma
Chronic Obstructive Pulmonary Disease (COPD), Exacerbation Copd
Determinants of Lower Limb Muscle Atrophy Induced During an Hospitalization for Exacerbation of COPD
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airway obstruction and inflammatory response of the lungs and bronchi.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Exacerbation Copd, Muscle Atrophy
- Trial name
- AMI-EX-BPCO (NCT03153826)
- Testing
- Comparison of clinical and biological characteristics of patients
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Montpellier
Obstructive Chronic Pulmonary Disease, Emphysema
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype
AIM: To identify those mechanisms involved in the systemic and muscular response to exercise treatment, in two different Obstructive Chronic Pulmonary Disease (COPD) phenotypes (emphysema and non-emphysema).
- Conditions
- Obstructive Chronic Pulmonary Disease, Emphysema, Chronic Bronchitis
- Trial name
- NCT01431625
- Testing
- Combined Training (endurance and strength exercises)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Crohns Disease
Treatment of Moderate to Severe Refractory Crohn's Disease
This research study is testing an investigational research product called TRX103 as a possible treatment for individuals suffering from Crohn's Disease (CD).
- Trial name
- NCT06721962
- Testing
- TRX103, Cyclophosphamide
- Where
- 13 sites in United States
- Volunteers
- 39 people
- Sponsor
- Tr1X, Inc.
Exercise, Diet Interventions
Multimodal Intervention for Early Chronic Kidney Disease in Young People: Dysbiosis and Inflammation (CKD)
Chronic kidney disease (CKD) is a progressive condition associated with substantial morbidity, mortality, and healthcare costs. Early detection and timely intervention are critical to modify disease trajectory, particularly in…
- Conditions
- Exercise, Diet Interventions, Symbiotic, CKD Stage 1
- Trial name
- CKD (NCT07483697)
- Testing
- symbiotic
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Centenario Hospital Miguel Hidalgo