Clinical trials: Inflammation Function
Calcific Aortic Valve Disease, Inflammation
Impact of TAVI on the Gut Microbiota and Its Metabolites
Aortic stenosis is a common heart valve disease in older adults. It occurs when the aortic valve becomes narrowed, making it harder for blood to flow from the heart to the rest of the body.
- Conditions
- Calcific Aortic Valve Disease, Inflammation, Dysbiosis, TAVI
- Trial name
- Swiss-GUT-TAVI (NCT07565077)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pneumonia, Peritonitis
Functional Genomic Influences on Disease Progression and Outcome in Sepsis
The proposal is aimed at identifying genetic factors that determine the incidence and severity of, and the outcome from life-threatening infections (severe sepsis/septic shock) in patients admitted to High Dependency Units (HDUs)…
- Trial name
- GAinS (NCT00131196)
- Where
- 50 sites in United Kingdom
- Volunteers
- 4,000 people
- Sponsor
- University of Oxford
Leukocytosis, Triglycerides
Acute High Fat Bulletproof Coffee vs Black Coffee on Metabolism, Inflammation and Cognitive Function in Healthy Adults
This study will determine whether acute ingestion of a high fat "Bulletproof Coffee" will lead to changes in plasma triglycerides, immune cell function, as well as cognitive function when compared to a black coffee.
- Conditions
- Leukocytosis, Triglycerides, Cognitive Function, Inflammatory Response
- Trial name
- NCT04307979
- Testing
- High-fat coffee, Black coffee
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Radiotherapy, Inflamation
Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy.
Breast cancer and its treatment with radiotherapy may be associated with systemic inflammatory, hematological, cardiac, body composition, functional and quality-of-life alterations.
- Conditions
- Radiotherapy, Inflamation, Immune System, Physical Fitness
- Trial name
- NCT07583719
- Testing
- Moderate-Intensity Interval Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Diet, Healthy
Investigate Beneficial Effect of Herbal Tea in Jordanian Adults
investigate beneficial effect of an herbal tea prepared from carob pulp and pods (Ceratonia siliqua), anise seed (Pimpinella Anisum L), wild thyme, green tea and eucalyptus leaves with Manuka honey (natural sweetener) on lipid…
- Trial name
- herbaltea (NCT04093128)
- Testing
- herbal tea intervention
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr.Ruba Musharbash
Metabolic Syndrome
Effects of Low Fat Milk Consumption on Metabolic Syndrome
This study aimed to investigate the effects of low-fat milk consumption on metabolic parameters and biomarkers related to inflammation, oxidative stress, and endothelial function in Korean adults with metabolic syndrome.
- Trial name
- NCT02028585
- Testing
- Low-fat milk group
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ministry of Food and Drug Safety, Korea
Sickle Cell Anemia
Establishment of Functional MRI Imaging Parameters for Use in the Evaluation of Sickle Cell Disease
Patients with sickle cell anemia (SCA) are at an increased risk for damage to brain tissue due to their disease. The investigators are interested in how blood flow and cerebral inflammation are different in SCA patients and how…
- Trial name
- NCT02445144
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Cardiovascular Disease, Chronic Kidney Failure
Effect of HCO1100 on Cardiovascular Function
The purpose of this study is to determine whether high porous membranes are effective in the treatment of cardiovascular events in chronic dialysis patients.
- Trial name
- HicoCARD (NCT01363921)
- Testing
- HCO 1100
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Vantive Health LLC
Obesity and Overweight
Neurological Impact of Weight Reduction and Fitness Interventions
This study will test how significant weight loss through bariatric surgery, combined with a personalised exercise program, affects brain inflammation.
- Trial name
- NeuroFit (NCT06830252)
- Testing
- Exercise
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- University of Sydney
Liver Enzymes, Inflammatory Markers
Moderate Intensity Intermittent Walking in Postmenopausal Women
The goal of this clinical trial is to investigate the impact of a walking training intervention program on liver enzymes and selected inflammatory markers in postmenopausal women with obesity.
- Trial name
- NCT06809270
- Testing
- Walking training intervention
- Where
- Tunisia
- Volunteers
- 36 people
- Sponsor
- Wissal Abassi
Cardiometabolic Risk, Abdominal Obesity
Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention
The aim of the study is to evaluate the synergistic effects of daily consumption of food products fortified with bioactive components (fibres, polyphenols, omega-3, Slow Digestible Starch) for 9 weeks, compared to the daily…
- Trial name
- SINFONI (NCT04190706)
- Testing
- bioactive components fortified food products intake (biscuits and cookies), control food products intake (biscuits and cookies)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Metabolic Syndrome
Effects of Nut Consumption on Metabolic Syndrome
This study aimed to investigate the effects of nut consumption on metabolic parameters and biomarkers related to inflammation, oxidative stress, and endothelial function in Korean adults with metabolic syndrome.
- Trial name
- NCT02023749
- Testing
- Nut group
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Food and Drug Safety, Korea
Diabetes Type 2
Effects of Different Doses of Aspirin on Pathophysiological Markers in Type 2 Diabetes
This study was set up to assess the effects of different doses of aspirin when compared with placebo (dummy drug), used sequentially over a 2 week study period with a 2 week wash-out (rest period) in between, in people with…
- Trial name
- NCT00898950
- Testing
- Aspirin
- Where
- 2 sites in United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Portsmouth
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Inflammation
Strength Training Induced Alterations in Markers of Immune Function
Exercise has been used to help prevent or slow the progression of inflammation-related disease; however, the mechanism by which this activity may lower concentrations of inflammatory markers remains unclear.
- Trial name
- NCT01450852
- Testing
- Strength Training
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Rest, Training
The Effect of Cryostimulation on Inflammation and Motor Functions. The Study Was Conducted to Determine the Effect of Five Days of Whole-body Cryostimulation (PBC) on Reducing Inflammation and Improving Motor Skills in Soccer Players
The aim of the study was to determine the effect of a 5-day PBC on reducing inflammation and improving motor skills in soccer players during the initial phase of the training period.
- Trial name
- NCT06549933
- Testing
- Criostymulation
- Where
- Poland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Locally Advanced Breast Cancer (LABC), Postoperative Inflammation
Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy
This study evaluates whether preoperative shoulder range-of-motion exercises influence postoperative inflammatory response, pain, shoulder function, and quality of life in patients with locally advanced breast cancer undergoing…
- Conditions
- Locally Advanced Breast Cancer (LABC), Postoperative Inflammation, Prehabilitation
- Trial name
- NCT07420335
- Testing
- Preoperative shoulder exercise, Standard preoperative care
- Where
- Indonesia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Coronary Artery Disease, Atherosclerosis
Cardiac Rehabilitation and Coronary Artery Disease
Patients with coronary artery disease (CAD) aged 40-70 years will undergo exercise training (thrice weekly for 12 weeks). A reference group composed of healthy individuals will be included.
- Trial name
- NCT06579807
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Neutrophil Lymphocyte Ratio, Serum Createnine
Does Preconditioning Affects Other Organs in Patients Undergoing Open Heart Surgery ?
An association between white blood cell count (WBC), neutrophil-lymphocyte ratio , and inflammatory process is well known . Ischemic preconditioning reduces the inflammation
- Conditions
- Neutrophil Lymphocyte Ratio, Serum Createnine, Mechanical Ventilation
- Trial name
- NCT03097692
- Testing
- ischemic preconditioning, Pharmacologic preconditionig
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Severe Sepsis
The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis
The purpose of this study is to evaluate the efficacy of Si-Ni-Tang (a Chinese Herbal Formula documented in Shang Han Lun) in treating severe sepsis.
- Trial name
- NCT02777606
- Testing
- Si-Ni-Tang
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine