Clinical trials: Inflammation Function
Irritable Bowel Syndrome, Metabolic Syndrome
Evaluation of Dietary Supplementation in Patients With Gastrointestinal Disorders.
The term "inflammaging" describes the aging process characterized by a chronic low-grade inflammatory state. With advancing age, this condition is often associated with cardiovascular disease, diabetes, and neurodegenerative…
- Trial name
- TrioB (NCT06960941)
- Testing
- TrioBiotix360®, Booklet with a series of postural hygiene exercises
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Systemic Lupus Erythematosus, Cardiovascular Disease
The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD
Background: People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. This can increase the risk of heart attacks or stroke.
- Conditions
- Systemic Lupus Erythematosus, Cardiovascular Disease, Premature Atherosclerosis
- Trial name
- NCT05440422
- Testing
- anifrolumab
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Acute Coronary Syndrome
Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary Stenting
To investigate pleiotropic effects of ticagrelor in addition to its antiplatelet effects in type 2 diabetic patients with non-ST elevation acute coronary syndrome by measuring inflammatory markers, circulating number of…
- Trial name
- NCT02487732
- Testing
- Ticagrelor, Prasugrel
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Korea University Anam Hospital
Inflammatory Bowel Diseases
Assessing Cardiovascular Dysfunction Pre- & Post-treatment in Inflammatory Bowel Diseases
The aim of this study is to compare medical and surgery treatment in IBD patients and healthy controls, by assessing the endothelial and cardiac function and the inflammation status.
- Trial name
- NCT03615287
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Hypertension
Blood Pressure Lowering Effects of Grape Juice
Recent studies suggest that a diet rich in fruit and vegetables can lower blood pressure, and a number of lines of evidence suggest that grape products may have such an effect.
- Trial name
- NCT00302809
- Testing
- Concord Grape Juice
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston University
Lung Cancer
Studies of Phenotypic and Functional Characteristics of Circulating Neutrophil Subpopulations in Patients With Lung Cancer
The objective is to study the phenotypic, functional and metabolomic characteristics of neutrophils circulating subpopulations in lung cancer patients, and to compare them to a control group of healthy volunteers.
- Trial name
- PNN-CP (NCT06244355)
- Testing
- Extra blood tubes
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV-Associated Cognitive Motor Complex
Mild Neurocognitive Disorder in HIV Infection of the Brain
Background: Some people with human immunodeficiency virus (HIV) develop problems with thinking and concentration when the virus affects the brain. This is known as mild neurocognitive disorder (MND).
- Trial name
- NCT01547754
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Heart Failure With Reduced Ejection Fraction
Comparison of Effects of Atorvastatin Versus Rosuvastatin on Cardiac Function in Heart Failure Patients
Statins have a protective effect in patients with established heart failure because of their lipid-lowering and pleiotropic effects.
- Trial name
- ASTRO-CHF (NCT05072054)
- Testing
- Atorvastatin Oral Tablet, Rosuvastatin Oral Tablet
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Unruptured Cerebral Aneurysm, Hemifacial Spasm
Effect of Acupuncture on Inflammation and Immune Function After Craniotomy
The aim of this study is to evaluate the effect of acupuncture on inflammation and immune function after craniotomy. This study will be a single-center, parallel group clinical trial that will be conducted at Kyung Hee University…
- Conditions
- Unruptured Cerebral Aneurysm, Hemifacial Spasm, Brain Tumor
- Trial name
- NCT02761096
- Testing
- acupuncture, conventional treatment
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Kyunghee University Medical Center
Sepsis
The Effect of Rhubarb on Sepsis and Post-traumatic Gastrointestinal Function Failure
Random grouping by computer, divided into two groups, a group of rhubarb treatment group, another group for the placebo group.
- Trial name
- NCT03048903
- Testing
- Rheum Palmatum Root, Starch Corn
- Where
- China
- Volunteers
- 400 people
- Sponsor
- CHEN De-chang
Hypogonadotropic Hypogonadism, Type 2 Diabetes
Hypogonadism in Young Men With Type 2 Diabetes
Low testosterone production, known clinically as hypogonadism, appears to be common complication of type 2 diabetes, affecting one in three diabetic men.
- Trial name
- NCT01155518
- Testing
- testosterone, clomiphene
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- State University of New York at Buffalo
Coronary Artery Disease
The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention
The Efector study is an open, randomized and controlled trial assessing the effect of regular exercise training on endothelial function, inflammatory markers, progression of disease, heart rate variability and mental health in…
- Trial name
- EFECTOR (NCT00469950)
- Testing
- exercise training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Cystic Fibrosis, Cystic Fibrosis-related Diabetes
A CFit Study - Acute Exercise
A great medical success is the increase in the median survival age associated with cystic fibrosis (CF). However, this success has led to a new era of research aiming to maximise the quality of life (QoL) of the aging CF…
- Trial name
- NCT03237767
- Testing
- MIE, HIIE
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- University of Portsmouth
Sepsis, Immune System Disorder
The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis
The investigators aim to evaluate the roles of Th17/Treg cells and IL-23/IL-17 axis in the mechanisms of early enteral nutrition (EEN) correcting immune imbalance of sepsis by means of improving the intestinal flora disturbance.
- Conditions
- Sepsis, Immune System Disorder, Enteral Feeding
- Trial name
- NCT03385850
- Testing
- enteral nutrition
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Obstructive Sleep Apnea of Adult
A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients
Sleep apnea is a common under-diagnosed medical disorder, and moderate to severe disease is found in approximately 9% of men and 4% of women.
- Trial name
- NCT05009901
- Testing
- Alpha Lipoic Acid 600 MG Oral Tablet
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Alzheimer Disease
Biomarkers for Monitoring Dementia Progression
The variable course of Alzheimer's disease (AD) and the paucity of adequate cures urges to implement new strategies for its early detection and clinical intervention.
- Trial name
- ADvance (NCT06855368)
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele Roma
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
Inflammation
Fish Oil (Omega 3), Immune Function, and Mood
This study is designed to examine the effects of fish oil on immune function and mood.
- Trial name
- NCT00385723
- Testing
- Omega 3 (Fish Oil) Supplementation
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pre-hypertension, JNC 7 Stage I Hypertension
Center of Research Translation (CORT) Project 2
We propose a novel intervention for reducing BP that could have a preferential impact in patients with hyperuricemia and gout. There is a great need for new anti-hypertensives, particularly among those with gout.
- Trial name
- NCT02038179
- Testing
- Allopurinol
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Airway Inflammation, Asthma
An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients
This is a randomised, active-comparator, open-label, parallel-group, multicentre phase IV exploratory study to characterise changes in airway inflammation, symptoms, lung function, and reliever use in asthma patients using SABA…
- Trial name
- NCT03924635
- Testing
- SYMBICORT and salbutamol
- Where
- 6 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- AstraZeneca