Clinical trials: Inflammation Function
HIV Infection
Functional Interval Training for Veterans Exercising Through Telehealth.
Most Veterans living with HIV are 50 years of age or older and can expect to live more than 20 years longer with HIV medication.
- Trial name
- FIT-VET (NCT04103593)
- Testing
- exercise training
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- VA Office of Research and Development
Sepsis, Shock, Septic
"Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools"
The mini fluid challenge (mini_FC) is a functional hemodynamic test which has been used in different clinical contexts to assess fluid responsiveness.
- Conditions
- Sepsis, Shock, Septic, Critically Ill
- Trial name
- MINI3 (NCT04934943)
- Testing
- mini_FC
- Where
- 2 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Humanitas Clinical and Research Center
Asthma Attack, Lung Function
Cost Effective Air Filtration Intervention in Low-Income Housing to Reduce Asthma Morbidity
This project will investigate the effectiveness of HEPA air cleaners in reducing indoor air pollution and improving asthma morbidity in children living in East Harlem, New York City (NYC).
- Conditions
- Asthma Attack, Lung Function, Airway Inflammation
- Trial name
- NCT07116460
- Testing
- Austin Air Cleaner
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Human Immunodeficiency Virus (HIV), Vitamin D Deficiency
Study of Vitamin D and Effect on Heart Disease and Insulin Resistance
The purpose of this study is to evaluate how Vitamin D affects endothelial function, inflammation, lipids, insulin resistance, vitamin D levels, and parathyroid hormone (PTH).
- Conditions
- Human Immunodeficiency Virus (HIV), Vitamin D Deficiency, HIV Infections
- Trial name
- NCT01093417
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University Hospitals Cleveland Medical Center
Ischemic Stress, Transient Non-Lethal Ischemia
The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress
Many studies have shown that if the human body is stressed by a lack of blood flow for a short period of time, the body develops defenses to make the body more resistant to a future stress from lack of blood flow.
- Trial name
- NCT00250185
- Testing
- Sodium Nitrate, Acetylcholine
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cirrhosis
Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) present in cirrhotic patients induces severe circulatory dysfunction, which results in renal failure in up to 30% of the patients.
- Trial name
- Infecir (NCT00124228)
- Testing
- Human Albumin
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Hospital Clinic of Barcelona
HIV Infection, Inflammation
Effect of Raltegravir on Endothelial Function in HIV-Infected Patients
Recent studies suggest that HIV patients are at increased risk for cardiovascular events; however, the mechanisms underlying this increased risk remain unclear.
- Conditions
- HIV Infection, Inflammation, Cardiovascular Disease, HIV Infections
- Trial name
- NCT00843713
- Testing
- raltegravir
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2
Examining the Effect of Exogenous Ketone Supplementation on Glucose Control in Type 2 Diabetes
Ketone bodies are a fuel source and signaling molecule that are produced by the body during prolonged fasting or if an individuals consistently eats a low-carbohydrate "keto" diet.
- Trial name
- NCT05155410
- Testing
- Exogenous Ketone Monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Gastric Cancer, Enteral Immunonutrition
Effect of Enteral Immunonutrition on Immune, Inflammatory Markers and Nutritional Status in Patients Undergoing Gastrectomy for Gastric Cancer
Enteral immunonutrition (EIN) has been gaining increasing attention, but data of its immune and anti-inflammatory function in patients undergoing gastrectomy for gastric cancer are poorly investigated.
- Trial name
- NCT03730545
- Testing
- enteral immunonutrition
- Volunteers
- 124 people
- Sponsor
- West China Hospital
Hypertension, Sodium Excess
Effects of Salt on Serum Osmolarity and Hemodynamics Parameters
Diets containing excessive salt (>12 g/day) have negative effects on kidney and cardiovascular system. Considering this known fact, the investigators aimed to study if the amount of the water taken with excessive salt had any…
- Conditions
- Hypertension, Sodium Excess, Oxidative Stress, Inflammation
- Trial name
- NCT03314727
- Testing
- High salt (NaCl) intake
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koç University
Alcohol Use Disorder
Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder
The goal of this clinical trial is to identify sex-specific biomarkers that confer greater susceptibility for Alcohol Use Disorder (AUD) and differentiate how treatment response varies by sex in people with Alcohol Use Disorder.
- Trial name
- ABSTAIN (NCT06426303)
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Milky Kohno
Sepsis, Septic Shock
Improvement of Organ Function by Apigenin in Elderly Patients With Sepsis
In this single-center, randomized, single-blind, placebo-controlled pilot clinical trial. The effect of apigenin on the improvement of organ function will be investigated in elderly patients with sepsis.
- Trial name
- NCT05999682
- Testing
- apigenin, sterilized water
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
Functional Dyspepsia, Epigastric Pain Syndrome
Cognitive Behavioral Therapy for Functional Dyspepsia (Epigastric Pain Syndrome and Postprandial Distress Syndrome Subtypes)
The goal of this clinical trial is to learn whether adding Cognitive Behavioral Therapy (CBT) to standard medical treatment can improve symptoms in adults with Functional Dyspepsia.
- Conditions
- Functional Dyspepsia, Epigastric Pain Syndrome, Postprandial Distress Syndrome
- Trial name
- FD-CBT (NCT07577089)
- Testing
- Optimized Standard Treatment (OPT), Cognitive Behavioral Therapy + Optimized Standard Treatment (CBT + OPT)
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Healthy
Effect of MOF on Exercise Blood Pressure
The purpose of this study is to establish an effect of monomeric and oligomeric flavanols supplementation on exercise blood pressure and vascular function in healthy volunteers.
- Trial name
- NCT04907097
- Testing
- Monomeric and oligomeric flavanols
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Reperfusion Injury, Liver Injury
Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation
This blinded, placebo-controlled study will administer inhaled nitric oxide to patients undergoing liver transplantation. The purpose of the study is to test if inhaled nitric oxide prevents liver injury associated with the…
- Trial name
- NCT00582010
- Testing
- inhaled nitric oxide, nitrogen gas
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Chronic Total Occlusions of Coronary Arteries, Stress Echocardiography (SE)
Predicting Functional Recovery After Coronary Chronic Total Occlusion Revascularization
Chronic total occlusion (CTO) is defined as complete coronary occlusion with TIMI flow grade 0 persisting for more than three months, identified in 15-25% of patients undergoing coronary angiography.¹,² CTO is associated with…
- Conditions
- Chronic Total Occlusions of Coronary Arteries, Stress Echocardiography (SE), Inflammation Biomarkers
- Trial name
- StressECHOCTO (NCT07879573)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Liver Transplant; Complications
Von Willebrand Factor and Protein C Ratio in Graft Function After Liver Transplant
In liver cirrhosis (LC),the activity of von Willebrand factor (vWF)-cleaving enzyme ADAMTS13 is reduced in LC patients and consequent progression of liver injury.
- Trial name
- NCT04324255
- Testing
- LT
- Where
- South Korea
- Volunteers
- 1,199 people
- Sponsor
- Asan Medical Center