Clinical trials: Inflammation Indices
Knee Osteoarthritis, Osteoarthritis
Blood Cell Ratios as Predictors of Response to Platelet-Rich Plasma in Knee Osteoarthritis
Intra-articular platelet-rich plasma (PRP) injection is a widely used treatment for knee osteoarthritis, but patients respond to it very differently and there is currently no simple, inexpensive way to predict who will benefit.
- Trial name
- PRP-NLR (NCT07617233)
- Where
- Cyprus
- Volunteers
- 120 people
- Sponsor
- Utku Gürhan
Septic Shock
Evaluation of New Hemodynamic Indices
The objective is to determine the sensitivity and specificity via Receiver Operating Characteristic (ROC) curve of Global Longitudinal Strain (GLS) The secondary objectives are the same for the change in the amount of carbon…
- Trial name
- EVOLVE (NCT03961594)
- Testing
- expansion volémique
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Sepsis, Septicemia
Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests
We propose to develop novel diagnostic tests for severe sepsis and community acquired pneumonia (CAP). This program, entitled Community Acquired Pneumonia \& Sepsis Outcome Diagnostics (CAPSOD), is a multidisciplinary…
- Conditions
- Sepsis, Septicemia, Sepsis Syndrome, Shock, Septic
- Trial name
- NCT00258869
- Where
- 3 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- National Center for Genome Resources
Periapical Periodontitis
Association of Apical Periodontitis With Hs-CRP and Hemogram Indices
There is lack of evidence on resolution of signs of systemic inflammatory markers by successful elimination of periapical inflammation by endodontic treatment.
- Trial name
- NCT04980768
- Testing
- Root canal treatment
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Shock, Septic, Hemodynamic Instability
Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?
We evaluated the ability of shock indices and hemodynamic parameters to predict 28-day ICU mortality.
- Trial name
- NCT06415006
- Testing
- Measurement of hemodynamic parameters.
- Where
- Turkey (Türkiye)
- Volunteers
- 1,522 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Neonatal Sepsis
White Blood Cells and Platelets Indices as a Prognostic Factor in Neonatal Sepsis
Sepsis is a complex condition initiated by a pathogen and mediated by cytokines followed by immune, inflammatory, and coagulation homeostasis disturbances, its evolution being dictated by a complicated balance between pro…
- Trial name
- NCT03880305
- Testing
- complete blood count
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Crush Syndrome, Rhabdomyolysis
Inflammation Indıces and Mortality in Adult Crush Syndrome
This single-center, retrospective observational cohort study evaluated the prognostic value of complete blood count-derived inflammatory indices - the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR)…
- Conditions
- Crush Syndrome, Rhabdomyolysis, Systemic Inflammatory Response, Critical Illness
- Trial name
- NCT07433127
- Where
- Turkey (Türkiye)
- Volunteers
- 325 people
- Sponsor
- Ataturk University
Obesity (BMI > 35), Morbid Obesity
Predictive Value of Nutritional and Inflammatory Indices for Postoperative Complications After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity, but postoperative complications remain an important cause of morbidity.
- Trial name
- BARI-NUTRI (NCT07747168)
- Testing
- Bariatric Surgery
- Where
- Greece
- Volunteers
- 600 people
- Sponsor
- G.Gennimatas General Hospital
Septic Shock, Morality
Shock Indices Use for Early Mortality From Septic Shock
Background and Rationale: Sepsis is a universal healthcare problem with a high incidence and mortality. Improvement in early sepsis recognition and management has reduced the 28 day- and in-hospital mortality in the last two…
- Trial name
- NCT05088109
- Testing
- early mortality prediction using septic shock indices
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Cairo University
Inflammation Indices, Late Onset Neonatal Sepsis
Late-Onset Neonatal Sepsis: A Case-Control Study
The diagnosis of late-onset sepsis in term neonates has been studied less than that of early-onset sepsis. Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers in the diagnosis of sepsis.
- Trial name
- Sepsis (NCT07635264)
- Testing
- serum biomarker
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mersin University
Cardiovascular Diseases, Hypertension
Impact of a Plant-Based Diet on Indices of Cardiovascular Health in African Americans
The role of diet in preventing hypertension and cardiovascular diseases in African Americans, who have a much higher risk of developing these diseases, is not well understood.
- Conditions
- Cardiovascular Diseases, Hypertension, Diet, Healthy
- Trial name
- NCT05344287
- Testing
- Typical American Diet, Plant-Based Diet
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
HIV Infections, HIV Seronegativity
A Study of Male Rectal Samples in Preparation for Future Rectal Microbicide Trials
Microbicides are drugs that destroy microbes such as viruses and bacteria. Rectal microbicides may be able to prevent transmission of HIV during anal intercourse.
- Trial name
- NCT00075062
- Testing
- Flexible Sigmoidoscopy, Rectal Biopsy
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Endometriosis
Effect of Quercetin Supplementation on Endometriosis Outcomes
Quercetin is a polyphenol compound that possesses anti-inflammatory properties and can be found in various food sources like apples, berries, cabbage, and onions.
- Trial name
- NCT05983224
- Testing
- Quercetin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- National Nutrition and Food Technology Institute
Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Hematological Indices and Sympathetic Block Response in Neuropathic Pain
This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as…
- Trial name
- HINSPAIN (NCT07596823)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Inflammation
Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population
The purpose of this study is to determine if a dried fruit and vegetable supplement (Juice Plus+) can alter the gut microbiome and improve gut permeability and inflammatory levels in an obese, stressed population.
- Trial name
- NCT02512107
- Testing
- Juice Plus+
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Multiple Myeloma
CBC-Based Inflammatory Indices in Newly Diagnosed Multiple Myeloma
Multiple myeloma is a type of blood cancer characterized by the abnormal growth of plasma cells in the bone marrow. Increasing evidence indicates that interactions between myeloma cells and the host immune-inflammatory response…
- Trial name
- NCT07823959
- Volunteers
- 60 people
- Sponsor
- Assiut University
Abdominal Sepsis, Critically Ill
Blood Indices of Systemic Inflammation in Critically Ill Patients With Abdominal Sepsis
This study aims to clarify the role of blood indices of systemic inflammation in ICU-admitted patients with abdominal sepsis to assess their diagnostic significance as well as their prognostic value.
- Trial name
- NCT06095830
- Testing
- Complete blood count
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Contraception
Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity
The purpose of this study is to compare the effects of oral versus patch administration of hormonal contraception on hormone sensitive proteins such as lipoproteins, clotting factors and inflammatory proteins as well as blood…
- Trial name
- NCT00439972
- Testing
- Ortho-Cyclen (R), Ortho Evra (R), extended use of Ortho Evra (R)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Washington
Metabolic Syndrome (MetS), Psychiatric Disorders
The Impact of the Mediterranean Diet on Anthropometric Indices, Lipid Profiles, Energy Metabolism Signaling Proteins and Inflammatory Cytokines in Psychiatric Patients With Metabolic Syndrome
Background: Dietary modifications, like changing macronutrient distribution and improving food quality, are the main therapeutic approaches for managing oxidative stress, inflammation, and metabolic syndrome.
- Conditions
- Metabolic Syndrome (MetS), Psychiatric Disorders, Mediterranean Diet, Inflammatory Cytokines
- Trial name
- NCT07164014
- Testing
- Mediterranean diet, Hospital diet
- Where
- Saudi Arabia
- Volunteers
- 144 people
- Sponsor
- King Saud University
Type 2 Diabetes, Inflammation
Low-Intermediate-Glycemic Index Caribbean Foods Versus High Glycemic Index Foods in Type 2 Diabetes
The purpose of this study is to determine whether low and intermediate GI Caribbean foods are effective in the management of type 2 diabetes.
- Conditions
- Type 2 Diabetes, Inflammation, Cardiovascular Disease
- Trial name
- NCT00818935
- Testing
- Low-Intermediate-Glycemic Index diets, High GI diet
- Where
- Jamaica
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital of the West Indies