Clinical trials: Inflammation Vascular
Psoriasis, Vascular Inflammation
Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis
This study is a double-blinded randomized multicenter placebo controlled trial to determine the effect of adalimumab on vascular inflammation (ascending aorta and carotides) in patients with moderate to severe psoriasis.
- Conditions
- Psoriasis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT01722214
- Testing
- Adalimumab
- Where
- 5 sites in Canada
- Volunteers
- 107 people
- Sponsor
- Innovaderm Research Inc.
Endothelial Dysfunction, Vascular Inflammation
Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular Inflammation
The purpose of this study is to compare the effects of ticagrelor and clopidogrel on endothelial dysfunction and vascular inflammation Ticagrelor will lead to beneficial pleiotropic effects compared with treatment with…
- Trial name
- NCT02379676
- Testing
- Ticagrelor, Clopidogrel
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Kiyuk Chang
Vascular Stiffness, Inflammation
Anthocyanin-rich Blackcurrant and Vascular Function
Regular consumption of fruits and vegetables may improve human health and reduce the risk of chronic diseases, such as heart disease, certain cancers and type 2 diabetes, but the active components and the underlying mechanisms…
- Trial name
- NCT02459756
- Testing
- Beverage: Spray dried blackcurrant powder dissolved in water
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Reading
Myocardial Infarction, Inflammation
Inflammation in Type 2 Myocardial Infarction
Type 2 myocardial infarction (MI) is defined as myocardial necrosis that results from an imbalance of myocardial oxygen supply and demand.
- Conditions
- Myocardial Infarction, Inflammation, Critical Illness
- Trial name
- NCT02385487
- Where
- United States
- Sponsor
- NYU Langone Health
Vascular Inflammation, Psoriasis
Cytokines and Vascular Inflammation in Psoriasis
Psoriasis is an inflammatory disease involving the skin, the joints and the vascular compartment. The mechanisms linking inflammation in the skin and joints and in the vascular walls are poorly understood.
- Conditions
- Vascular Inflammation, Psoriasis, Coronary Atherosclerosis
- Trial name
- NCT02305953
- Where
- 4 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Innovaderm Research Inc.
Metabolic Diseases, Endocrine System Diseases
Effect of Fish Oil (Omega-3 Fatty Acids) on Arteries
The overall objective of LUCHAR Specific Aims 4.1 and 4.2 is to assess the additional contribution of cardiovascular disease (CVD) risk markers to traditional biomedical risk factors in the prediction of pre-clinical CVD.
- Conditions
- Metabolic Diseases, Endocrine System Diseases, Heart Disease, Vascular Diseases
- Trial name
- NCT00935766
- Testing
- Omega-3
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Denver Health and Hospital Authority
HIV, Vascular Diseases
Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People
People infected with HIV have a greater risk of developing cardiovascular disease than people not infected with HIV. This may be due to increased inflammation in the blood vessels.
- Conditions
- HIV, Vascular Diseases, Cardiovascular Diseases, Atherosclerosis
- Trial name
- NCT00864916
- Testing
- Combination antiretroviral therapy (cART), Pentoxifylline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Indiana University
Glucose Tolerance, Lipid Homeostasis
Herbal Preparation and Glucose Homeostasis
Rationale: The incidence of obesity and type 2 diabetes (T2D) is increasing rapidly and accounts for a considerable part of health care costs.
- Conditions
- Glucose Tolerance, Lipid Homeostasis, Vascular Function, Inflammation
- Trial name
- Herbie (NCT02065271)
- Testing
- herbal supplement
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Vascular Calcification, Atherosclerosis
Atorvastatin Treatment to Attenuate the Progression of Cardiovascular Disease in Hemodialysis Patients
This prospective, randomized, controlled study aims to investigate the effects of atorvastatin treatment in hemodialysis patients concerning progression of coronary artery calcification, progression of carotid artery intima-media…
- Conditions
- Vascular Calcification, Atherosclerosis, Dyslipidemia, Inflammation
- Trial name
- NCT00481364
- Testing
- atorvastatin
- Where
- Turkey (Türkiye)
- Volunteers
- 446 people
- Sponsor
- Ercan OK
Vascular Health, Autonomic Function
Vascular and Neuro-inflammatory Effects of Endurance Exercise Training in African Americans
The purpose of this study is to test the effects of endurance exercise training on arterial structure and function, and to examine potential mechanisms producing changes in arterial structure and function in young (18-35 years of…
- Trial name
- VINE (NCT01024634)
- Testing
- Endurance Exercise
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Psoriasis, Vascular Inflammation
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis
This study is to determine the effect of adalimumab on inflammation of blood vessels that could lead to heart attack in patients with psoriasis.
- Conditions
- Psoriasis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT00940862
- Testing
- adalimumab, UVB Phototherapy, Topical treatment
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Innovaderm Research Inc.
Renal Dialysis, Cardiovascular Diseases
Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients
The aim of this cross-sectional study is to determine the correlation of coronary artery calcification as measured by electron-beam computerized tomography and coronary flow reserve measured by trans-thoracic Doppler…
- Conditions
- Renal Dialysis, Cardiovascular Diseases, Atherosclerosis, Inflammation
- Trial name
- NCT00921089
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Osteoporosis, Vascular Calcification
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
The purpose of this study is to determine if supplemental vitamin K will reduce age-related bone loss in elderly men and women above that achieved by supplementation.
- Conditions
- Osteoporosis, Vascular Calcification, Inflammation
- Trial name
- NCT00183001
- Testing
- Vitamin K
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Atherosclerosis, Vascular Disease
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
The purpose of this study is to determine if folic acid supplementation can slow down atherosclerotic progression, age-related cognitive decline and age-related hearing loss.
- Conditions
- Atherosclerosis, Vascular Disease, Cognitive Decline, Hearing Loss
- Trial name
- NCT00110604
- Testing
- folic acid (0.8 mg)
- Where
- Netherlands
- Volunteers
- 835 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Peripheral Vascular Disease, Intermittent Claudication
Balloon Angioplasty vs. Cutting Balloon Angioplasty of Femoropopliteal Arteries- a Randomized Controlled Trial
The purpose of this study to compare balloon angioplasty (PTA) vs. cutting balloon angioplasty (CB-PTA) in terms of patency and postintervention inflammation in peripheral artery disease.
- Conditions
- Peripheral Vascular Disease, Intermittent Claudication, Atherosclerosis, Angioplasty
- Trial name
- NCT00437905
- Testing
- angioplasty
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna