Clinical trials: Inflammatory Bowel Disease (IBD)
Crohn Disease
A Study on the Associations Between Microribonucleic Acid Gene Polymorphisms and Crohn's Disease
From January 2020 to January 2025, Crohn's disease (CD) patients and gender- and age-matched normal controls were collected from the Department of Gastroenterology, the Second Affiliated Hospital of Wenzhou Medical University.
- Trial name
- NCT06935929
- Testing
- Ustekinumab - Standard Dosage
- Where
- China
- Volunteers
- 839 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Inflammatory Bowel Diseases, Ulcerative Colitis
Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel Disease
Specific Aim 1: Characterize the effects of vitamin D treatment on expression of α4β7 on B cells in patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT04828031
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Stanford University
HELICOBACTER PYLORI INFECTIONS, Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis)
Prevalence of Helicobacter Pylori on Patients With Chronic Inflammatory Bowel Disease (IBD) at the CHU of Guadeloupe
Clinical and experimental data suggest that dysbiosis may play a pivotal role in the pathogenesis of intestinal bowel disease (IBD).
- Trial name
- HP-MICI (NCT07292454)
- Testing
- Biopsies
- Where
- Guadeloupe
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Ulcerative Colitis
A Study of Single and Multiple Ascending Doses of H021 in Healthy Participants
The primary purpose of this study is to evaluate the safety and tolerability of H021 tablets following oral administration of single and multiple ascending doses in healthy participants.
- Trial name
- NCT06627556
- Testing
- H021
- Where
- Australia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jiangsu Carephar Pharmaceutical Co., Ltd.
Crohn's Disease
Safety and Efficacy of ALX-0600 in Subjects With Active Crohn's Disease
The purpose of the study is to determine whether an investigational compound, ALX-0600, is safe and effective in treating Crohn's Disease.
- Trial name
- NCT00072839
- Testing
- ALX-0600, teduglutide 0.05, teduglutide 0.2 mg
- Where
- 26 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Shire
Vitamin D Substitution
Vitamin D Substitution During Winter Time
The purpose of this study is to confirm anticipated substitution dose of the vitamin D for sustained blood level during winter time in patients with inflammatory bowel diseases (IBD)
- Trial name
- NCT02958501
- Testing
- Colecalciferol
- Where
- Czechia
- Volunteers
- 176 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Ulcerative Colitis Mild, Ulcerative Colitis
Treatment of UC With Novel Therapeutics
This study is a clinical trial being done to investigate the efficacy of drug BRS201 as a treatment in patients with active mild ulcerative colitis.
- Trial name
- TURTLE (NCT06420375)
- Testing
- BRS201
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Inflammatory Bowel Diseases, Colitis, Ulcerative
Therapeutic Endpoint in Pediatric IBD Conditions
The purpose of this clinical study is the development of physiologic endpoint of inflammation in pediatric patients diagnosed with inflammatory bowel disease (IBD), specifically subtypes Crohn's disease (CD) and ulcerative…
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohn Disease
- Trial name
- NCT06065228
- Testing
- AlgometRx Nociometer
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's National Research Institute
Healthy Nutrition
Dietary Impact on Intestinal Sulfate Metabolism
This is a 5-week crossover pilot study of 15 highly motivated healthy volunteers who will consume two 7-day intervention diets: 1) a diet low in sulfur-containing amino acids (Low-S diet), emphasizing plant-based foods and fat…
- Trial name
- NCT05333900
- Testing
- Plant-Based Diet then animal-based diet, Animal-based diet then plant-based diet
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS)
Enabling Microbiomics- Driven Personalized Nutrition
The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.
- Conditions
- Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Celiac Disease, Diarrhea
- Trial name
- EMPOWER (NCT06657001)
- Where
- United States
- Volunteers
- 4,001 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis
Evaluation of Early Mucosal Healing During Clinical Remission in Pediatric Ulcerative Colitis
Establishing that mucosal healing (MH) has occurred after therapy is an important treatment goal, and the gold standard is endoscopic evaluation. In UC it is unclear if clinical parameters are adequate.
- Trial name
- NCT03179865
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Wolfson Medical Center
Ulcerative Colitis
CP101 for the Treatment of Ulcerative Colitis
This is a dose ranging exploratory phase 1 pilot study to assess engraftment, safety, and efficacy of CP101, an oral microbiome therapeutic, in participants with active mild-to-moderate Ulcerative colitis.
- Trial name
- NCT05852574
- Testing
- CP-101
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Crohn Disease
Comparing Endoscopic Strictureplasty vs. Balloon Dilation in Crohn's Disease Strictures
Crohn's disease (CD) is an inflammatory bowel disease characterized by chronic ulcers, strictures, and penetrating lesions in the intestinal tract.
- Trial name
- ES vs BD in CD (NCT06203782)
- Testing
- endoscopic stricturoplasty, endoscopic balloon dilation
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Arthritis, Rheumatoid, Colitis, Ulcerative
A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants
The purpose of this study is to collect and evaluate the following information in relation to the safety and the efficacy of Jyseleca tablet (Filgotinib Maleate) 100 milligram (mg) and 200 mg in this post marketing setting: (1)…
- Trial name
- NCT06246123
- Testing
- Non-interventional
- Where
- 59 sites in South Korea
- Volunteers
- 2,040 people
- Sponsor
- Eisai Korea Inc.
IBD
A Trial Comparing the Incidence of Hypophosphatemia in Relation to Treatment With Iron Isomaltoside and Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia Due to Inflammatory Bowel Disease
Treatment with iron isomaltoside and ferric carboxymaltose in subjects with iron deficiency anaemia due to inflammatory bowel disease and comparison of the incidence of hypophosphatemia
- Trial name
- NCT03466983
- Testing
- Iron Isomaltoside, Ferric Carboxymaltose
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- Pharmacosmos A/S
Inflammatory Bowel Disease (IBD), Anemia
Study of DISC-0974-201 in Participants With IBD and Anemia
This is a Phase 2, multicenter, randomized, double-blind placebo-controlled study of DISC-0974 to evaluate safety, tolerability, and efficacy in participants with IBD and anemia of inflammation.
- Conditions
- Inflammatory Bowel Disease (IBD), Anemia, Inflammatory Bowel Disease (IBD); Anemia
- Trial name
- NCT07368972
- Testing
- DISC-0974
- Where
- 15 sites in United States
- Volunteers
- 21 people
- Sponsor
- Disc Medicine, Inc
Inflammatory Bowel Disease (IBD)
Impact of Transition Programs on Readiness and Quality of Life in IBD
This study is a randomized controlled trial comparing two transition models for adolescents with inflammatory bowel disease (IBD) moving from pediatric to adult care.
- Trial name
- NCT06946810
- Testing
- Combined visits-based transition, Letter-based transition
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Padova
Crohn Disease, Insomnia
CBT-I for Sleep, Pain, and Inflammation in Crohn's Disease
People with Crohn's disease often suffer from sleep problems. Long term, sleep problems may lead to more flares of Crohn's disease or other complications.
- Conditions
- Crohn Disease, Insomnia, Sleep Disturbance, Pain
- Trial name
- SPIN (NCT05034159)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Ulcerative Colitis
Rutin Therapy Role in Reducing Ulcerative Colitis Severity
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by oxidative stress and recurring inflammation in the colon. The condition can become chronic, spread, and lead to other complications.
- Trial name
- NCT07147842
- Testing
- Rutin 500 MG, fecal calprotectin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Crohn Disease (CD)
Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's Disease
The ADICROHN-3 study is a prospective, multicenter, open-label cohort study. Its design is supported by the following elements: The results of the ADICROHN pilot study (EudraCT No.
- Trial name
- ADICROHN3 (NCT07629245)
- Testing
- injection of thawed SVF
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.