Clinical trials: Inflammatory Bowel Diseases (IBD)
Ulcerative Colitis
Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative Colitis
Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).
- Trial name
- NCT06764706
- Where
- 57 sites in Germany
- Volunteers
- 200 people
- Sponsor
- AbbVie
Inflammatory Bowel Diseases
Identification of Scores Associated With a Favorable Clinical Response With Thiopurines in IBD Patients
Inflammatory bowel disease (IBD) groups together Crohn's Disease (CD) and ulcerative colitis (UC). Its prevalence is high representing approximately 0.4% of the population.
- Trial name
- SCORE1 (NCT02367326)
- Testing
- data collection
- Where
- 15 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Crohn's Disease
Study About the Effect of Doxycycline and Acetylcystein in the Treatment of CD-associated Fistulae
The investigators will study whether local instillation of Doxycycline and Acetylcystein results in fistula closure in CD patients.
- Trial name
- NCT01012726
- Testing
- Colonoscopy
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Gerhard Rogler
Inflammatory Bowel Disease, Colorectal Cancer
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease
Build a collection of fecal microbiota in order to determine the characteristics of gut microbiota associated with colorectal cancer in Inflammatory bowel disease (IBD).
- Trial name
- DYSCOLIC (NCT02726243)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Malnutrition, Inflammatory Bowel Disease 1
Pre-Operative Parenteral Nutrition in Malnourished Patients
Malnourished patients with IBD that receive pre-operative parenteral nutrition therapy will have fewer post-operative complications compared to malnourished patients that receive standard of care nutritional therapy.
- Trial name
- NCT02985489
- Testing
- Olimel Parenteral Nutrition
- Sponsor
- University of Calgary
Inflammatory Bowel Diseases
Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract that includes ulcerative colitis (UC) and Crohn's disease (CD) .
- Trial name
- NCT05967650
- Testing
- standard hepatitis B vaccine, accelerated HBV Vaccine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Inflammatory Bowel Diseases
Protocol for Optimizing Colonoscopy Preparation in Patients With Inflammatory Bowel Disease
Clinical trial evaluating efficacy of bowel cleansing solutions in patients with Inflammatory Bowel Disease.
- Trial name
- EII_Prep (NCT04411017)
- Testing
- Endoscopy
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Crohn Disease
Microbiome Modification to Enhance Stelara Response in Crohn's Disease
This pilot study is being completed to determine whether a low-serine diet vs a high serine diet will reduce inflammation and symptoms in Crohn's disease (CD), as well as determine whether a low-serine diet (vs.
- Trial name
- MIM-TESRIC (NCT04795960)
- Testing
- Low serine diet, High serine diet
- Where
- United States
- Sponsor
- University of Michigan
Crohn Disease, Ulcerative Colitis (UC)
Use of Psychologist-administered Cognitive Behavioral Therapy (CBT) or Self-administered CBT for the Treatment of Anxiety and/or Depression in Inflammatory Bowel Disease (IBD)
This is a prospective, single center, randomized treatment study to assess if anxiety and depression in participants with IBD can be improved with CBT compared to those treated with SKY.
- Trial name
- NCT05377840
- Testing
- Psychologist-administered Cognitive Behavioral Therapy, Self-Administered Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Yale University
Behcet's Syndrome, Intestinal Type
Pathogenesis of Intestinal Behcet's Syndrome
There is a direct interaction between food, intestinal flora and the intestinal barrier composed of intestinal epithelial cells and mucosal immunity, whose composition and functional alterations are theorized to be closely…
- Trial name
- NCT06026020
- Testing
- Biological samples collection
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Colitis, Ulcerative, Crohn Disease
Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study
The purpose of this study is to evaluate in a step-wise approach the disease drug-drug interaction (DDI) potential for vedolizumab to indirectly affect the exposure of cytochrome P-450 (CYP) substrate drugs by modulating…
- Trial name
- NCT02760615
- Testing
- Caffeine, Losartan, Omeprazole
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Takeda
Crohn Disease, Inflammatory Bowel Diseases
Cannabidiol Usage as an Adjunct Therapy for Crohn's Disease
To date, few studies have assessed the efficacy and safety of Cannabinoids, compounds derived from the Cannabis plant, in patients with Crohn's disease.
- Conditions
- Crohn Disease, Inflammatory Bowel Diseases, Cannabis
- Trial name
- NCT03467620
- Testing
- Cannabidiol
- Sponsor
- University of Illinois Chicago
Inflammatory Bowel Diseases
Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients
The research is studying virtual reality (VR)-directed brain-gut behavioral therapy (BGBT) as a pain treatment option for hospitalized patients with inflammatory bowel disease (IBD).
- Trial name
- NCT06188793
- Testing
- Virtual reality-directed BGBT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Ulcerative Colitis, Ulcerative Colitis Chronic
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD).
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
- Trial name
- SHINE-ON (NCT04844606)
- Testing
- Mirikizumab
- Where
- 69 sites in United States, Austria and 14 more
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Crohn's Disease
Oral Administration of AlequelTM for Patients With Inflammatory Bowel Disease (IBD)
Oral administration of Alequel, a mixture of proteins derived from the patient's bowel will be tested in patients with inflammatory bowel disease.
- Trial name
- NCT02185183
- Testing
- Alequel
- Volunteers
- 22 people
- Sponsor
- Hadassah Medical Organization
Colitis, Ulcerative
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC)
The purpose of this study is to evaluate: a) the efficacy of ustekinumab dosing in inducing clinical remission, b) safety profile of ustekinumab, and c) ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with…
- Trial name
- UNIFI Jr (NCT04630028)
- Testing
- Ustekinumab Dose Based on BSA and Body Weight
- Where
- 58 sites in United States, Belgium and 7 more
- Volunteers
- 112 people
- Sponsor
- Janssen Research & Development, LLC
Inflammatory Bowel Disease
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of MT-1303 in Subjects With Inflammatory Bowel Disease
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of a single oral dose of MT-1303 in subjects with inflammatory bowel disease.
- Trial name
- NCT01666327
- Testing
- MT-1303
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Tanabe Pharma Corporation
Ulcerative Colitis, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for Ulcerative Colitis
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome.
- Trial name
- NCT03804931
- Testing
- Fecal microbiota transplantation, Infusion of Saline, 5-Aminosalicylic acid(5-ASA) and/or Prednisone
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guangzhou First People's Hospital
Crohn's Disease (CD), Dysmenorrhea Primary
Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)
The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's…
- Trial name
- AVID-CD (NCT07337902)
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Crohn's Disease, Inflammatory Bowel Disease
Safety and Treatment Effect of QBECO in Moderate to Severe Crohn's Disease
The purpose of this study is to evaluate the safety profile and to obtain an indication as to the therapeutic effect of QBECO induction treatment on clinical improvement in moderate to severe Crohn's Disease.
- Trial name
- NCT01809275
- Testing
- QBECO
- Where
- 4 sites in Canada
- Volunteers
- 68 people
- Sponsor
- Qu Biologics Inc.
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