Clinical trials: Inflammatory Bowel Diseases (IBD)
Lower Urinary Tract Symptoms, Colorectal Disorders
Lower Urinary Tract and Sexual Function in Women Following Surgery for Colorectal Disorders
This is a prevalence study evaluating lower urinary tract, prolapse, bowel, and sexual symptoms in women with a colorectal disorder who are planning to undergo surgery.
- Trial name
- NCT00667550
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, Irvine
Crohn's Disease
Switching From Adalimumab to Infliximab
Switching to Adalimumab has proven to be efficacious in Crohn's disease (CD) patients with intolerance or loss of response to Infliximab.
- Trial name
- ADA-IFX (NCT01338740)
- Testing
- Adalimumab and Infliximab
- Where
- 16 sites in Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Ghent
Ulcerative Colitis
Angiographic Delivery of AD-MSC for Ulcerative Colitis
Researchers are trying to determine the safety and feasibility of using an adipose derived mesenchymal stem cell (MSC) to treat people with Ulcerative Colitis.
- Trial name
- NCT04312113
- Testing
- Adipose derived, autologous mesenchymal stem cells
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Colitis, Ulcerative
VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis
This is a study to understand if taking VTX002 daily as a tablet orally is safe and effective in participants diagnosed with moderate to severe ulcerative colitis (UC).
- Trial name
- NCT05156125
- Testing
- VTX002
- Where
- 77 sites in United States, Bulgaria and 12 more
- Volunteers
- 213 people
- Sponsor
- Oppilan Pharma Ltd
Ulcerative Colitis (UC)
Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies
Micronutrient deficiencies are common in ulcerative colitis (UC). Selenium deficiency is associated with worse disease outcomes including disease flares and need for surgery.
- Trial name
- Selenium-UC (NCT07427017)
- Testing
- Selenium supplementation
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Northwestern University
Moderate to Severe Ulcerative Colitis
Fecal Calprotectin Levels, Quality of Life, and Workability in Patients Suffering From Ulcerative Colitis Under Adalimumab Therapy - AdaProQuo
The objectives of this study are to explore the fecal calprotectin (fC) levels of UC patients under adalimumab therapy and the correlation with their general wellbeing (Quality of Life [QoL]), workability, and disease activity.
- Trial name
- AdaProQuo (NCT02092389)
- Volunteers
- 10 people
- Sponsor
- AbbVie
Crohn's Disease (CD)
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with vedolizumab.
- Trial name
- NCT04779320
- Testing
- Vedolizumab IV
- Where
- 96 sites in United States, Australia and 16 more
- Volunteers
- 120 people
- Sponsor
- Takeda
Colitis, Ulcerative
Golimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic Remission
This is an open-label, phase IV trial. Adult patients, with moderately to severe, steroid dependent, acute ulcerative colitis not previously exposed to anti-TNF, will receive subcutaneous golimumab treatment, according to EU…
- Trial name
- UC-GOL (NCT02412085)
- Testing
- Golimumab
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas
Crohn's Disease, Ulcerative Colitis
The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation
Fifty patients will get probiotics (109 bacteria [L. acidophilus, B. bifidum, S. thermophilus, L. rhamnosus, L. casei] in 2 capsules) and half will get placebo (2 capsules that look the same like the probiotic capsules and will…
- Trial name
- NCT01078935
- Testing
- probiotics
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Ulcerative Colitis, Pouchitis
Clotrimazole Enemas for Pouchitis in Children and Adults
Colectomy with creation of an ileal pouch (IPAA) is now the treatment of choice for patients with ulcerative colitis that is resistant to existing medical therapies.
- Conditions
- Ulcerative Colitis, Pouchitis, Ileitis, Inflammatory Bowel Disease
- Trial name
- CAPTURE (NCT00061282)
- Testing
- Clotrimazole
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Web
Inflammatory Bowel Diseases
Remote Physiologic Monitoring to Detect Inflammatory Bowel Disease (IBD) Flares: A Feasibility Study
Inflammatory bowel disease (IBD) has become a more prominent disease in the US population, with more than 3 million adults in the US affected.
- Trial name
- NCT04333810
- Testing
- Whoop strap 3.0
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Crohn Disease, Inflammatory Bowel Diseases
Cannabidiol Usage as an Adjunct Therapy for Crohn's Disease
To date, few studies have assessed the efficacy and safety of Cannabinoids, compounds derived from the Cannabis plant, in patients with Crohn's disease.
- Conditions
- Crohn Disease, Inflammatory Bowel Diseases, Cannabis
- Trial name
- NCT03467620
- Testing
- Cannabidiol
- Sponsor
- University of Illinois Chicago
COVID-19, Perception, Self
The Impact of COVID-19 on the Health Care Utilization of Inflammatory Bowel Disease
The rapid spread of COVID-19 is expected to have a significant impact on medicine as well as all sectors worldwide. In particular, inflammatory bowel disease (IBD) is a chronic immune disease in which remission and activation are…
- Conditions
- COVID-19, Perception, Self, Facilities and Services Utilization
- Trial name
- NCT04387279
- Testing
- Interview
- Where
- South Korea
- Volunteers
- 800 people
- Sponsor
- Keimyung University Dongsan Medical Center
Crohn Disease
Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients
The purpose of this study is to use diet and an injectable medication called tirzepatide (Zepbound) glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist (GIP-GLP-1 RA) medication as adjunctive…
- Trial name
- NCT06774079
- Testing
- Tirzepatide, Mediterranean diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Inflammatory Bowel Diseases
Prevention of Inflammatory Bowel Diseases in Persons at Risk The PIONIR (Preventing IBD Onset in Individuals at Risk) Trial
The goal of this study is to explore in a cross over randomized controlled trial, the ability of the Tasty\&Healthy dietary intervention (NCT04239248) to alter the parameters associated with future risk of developing Chron's…
- Trial name
- PIONIR (NCT05211518)
- Testing
- Tasty&Healthy, Habitual diet
- Where
- Israel
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Inflammatory Bowel Diseases
A Gratitude Intervention in Improving Well-being and Coping in People Living With Inflammatory Bowel Disease
The primary aim of the proposed research is to investigate the extent to which a one-week online gratitude intervention can improve levels of wellbeing in individuals living with Inflammatory Bowel Disease (IBD).
- Trial name
- NCT03059186
- Testing
- Gratitude diary
- Where
- United Kingdom
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Crohn Disease, Infliximab
Combined Immunosuppression for Pediatric Crohn's Disease
This is a randomized controlled trial to compare the efficacy and safety of infliximab and immunosuppressives therapy alone or in combination for pediatric Crohn's disease.
- Conditions
- Crohn Disease, Infliximab, Immunosuppression, Children, Only
- Trial name
- NCT05043870
- Testing
- Infliximab and immunosuppressives, Infliximab
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Children's Hospital of Fudan University
Inflammatory Bowel Diseases
Comparison of Carbon Dioxide (CO2) to Air Insufflation in Colonoscopy in Patients With Inflammatory Bowel Disease
Patients with inflammatory bowel disease (IBD) frequently undergo endoscopic examination and may suffer from diagnostic procedures.
- Trial name
- CO2-IBD (NCT03282786)
- Testing
- carbon dioxide insufflation during colonoscopy
- Where
- Germany
- Volunteers
- 304 people
- Sponsor
- University Hospital Muenster
Crohn's Disease
Clinical Study of CDP870/Certolizumab Pegol in Patients With Active Crohn's Disease
This is a multi-centre, randomized, double-blind, dose response clinical study of CDP870 in patients with Crohn's disease.
- Trial name
- NCT00291668
- Testing
- Certolizumab Pegol
- Where
- 22 sites in Japan
- Volunteers
- 94 people
- Sponsor
- UCB Pharma
Inflammatory Bowel Diseases
Subcutaneous Interval Lengthening of Vedolizumab for Economic Research
Rationale: Subcutaneous vedolizumab is an effective maintenance therapy for patients with inflammatory bowel disease. Patients using subcutaneous vedolizumab (every 2 weeks) have higher vedolizumab serum trough concentrations…
- Trial name
- SILVER (NCT06584162)
- Testing
- Vedolizumab Injection
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
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