Clinical trials: Inflammatory Disorder
Ulcerative Colitis
Assessment of Pulmonary Involvement inUlcerative Colitis by Induced Sputum
Ulcerative colitis is a systemic disease we assume that extra intestinal involvement as we describein our study( Fireman Z, Osipov A, Kivity S, Kopelman Y, Sternberg A Fireman E: Assessment of pulmonary involvement in Crohn's…
- Trial name
- NCT00490048
- Testing
- Induced sputum (inhalation of 3.5% saline)
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Warfarin and NSAID
Warfarin and Non-Steroidal Anti-Inflammatory Drugs (NSAID) Customized Alert
The hypothesis is that a newly formatted electronic alert that requires the prescriber to pause and enter a specific "reason for override" on this alert, will cause prescribers in the intervention group to be significantly less…
- Trial name
- NCT00880932
- Testing
- Electronic Alert
- Where
- United States
- Volunteers
- 1,865 people
- Sponsor
- University of Pennsylvania
Crohns Disease
Oral N-acetylglucosamine in Crohn's Disease
Protein glycosylation is a critical post-translational modification that regulates protein trafficking and protein-protein interactions impacting a host of physiological processes.
- Trial name
- NAGIC (NCT07225998)
- Testing
- N-Acetylglucosamine (GlcNAc)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Crohn's Disease, Ulcerative Colitis
Telephone Consultation as a Substitute for Routine Out-patient Face-to-face Consultation for Children With Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) refers to two chronic diseases (Crohn's disease and ulcerative colitis) that affect the intestines.
- Trial name
- NCT02319798
- Testing
- telephone consultations, face-to-face consultations
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- Manchester University NHS Foundation Trust
Crohn's Disease
Autologous Hematopoietic Stem Cell Transplantation for Crohn's Disease Treatment
The purpose of this study is to evaluate the safety and potential clinical benefit of lymphoablation followed by autologous HSCT rescue in therapy refractory Crohn's disease
- Trial name
- HSCT (NCT01932658)
- Testing
- Hematopoietic stem cell transplantation
- Where
- United States
- Sponsor
- University of California, Los Angeles
Fatty Liver
Resveratrol in Patients With Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) and fatty liver hepatitis (NASH) are very common in the Western world and strongly associated with obesity. No known effective treatment is known.
- Trial name
- LIRMOI3 (NCT01464801)
- Testing
- Resveratrol
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- University of Aarhus
Inflammatory Bowel Disease
Characterization of Phenotype and Genotype of Early Onset Enteropathies
This study has been set up in order to characterize phenotypes and genotypes of patients with early onset enteropathies. In that goal, Investigators will collect biological samples (mainly blood) of patients suffering from early…
- Trial name
- IMMUNOBIOTA (NCT02614911)
- Testing
- Biological sampling
- Where
- 12 sites in France
- Volunteers
- 1,445 people, healthy volunteers welcome
- Sponsor
- Imagine Institute
Hyperuricemia, Metabolic Syndrome
Hyperuricemia and Left Ventricular Diastolic Function
Metabolic syndrome and hyperuricemia were both associated with inflammation, leading to diversities of cardiovascular disease such as left ventricular diastolic dysfunction, but the relationship among these entities remained…
- Conditions
- Hyperuricemia, Metabolic Syndrome, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT03495999
- Testing
- hyperuricemia
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- National Defense Medical Center, Taiwan
Necrotizing Enterocolitis
Administration of Arginine Supplementation in Preterm Infants
Calprotectin is a cytosolic component of neutrophils .Fecal calprotectin(FC) is a useful marker for exacerbation of inflammatory bowel disease in children .FC may be a useful marker for necrotizing enterocolitis (NEC).
- Trial name
- NCT01336998
- Testing
- arginine
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Alexandra Hospital, Athens, Greece
Bacteremia, Endocarditis
An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures
Although controversy exists regarding the efficacy of antibiotic prophylaxis for patients at risk of infective endocarditis, expert committees continue to publish recommendations for antibiotic prophylactic regimens.
- Trial name
- NCT06422221
- Testing
- Clindamycin, Doxycycline
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Santiago de Compostela
Sepsis
Curcumin in Critically Ill Patients With Sepsis
Sepsis is a life-threatening condition that occurs when the body's response to an infection becomes overwhelming and damages its own organs.
- Trial name
- NCT07436130
- Testing
- Curcumin
- Where
- Mexico
- Volunteers
- 56 people
- Sponsor
- Hospital Civil de Guadalajara
Non-inflammatory Degenerative Joint Disease
Multi-Center Comparative Trial of the ASR™-XL Acetabular Cup System vs. the Pinnacle™ Metal- on- Metal Total Hip System
The primary objective of this investigation is to evaluate the clinical and radiographic outcomes of the ASR™-XL Acetabular Cup System compared to the Pinnacle™ Acetabular Cup with a 28mm or 36mm ULTAMET™ metal insert.
- Trial name
- ASR (NCT00561600)
- Testing
- ASR™-XL Modular Acetabular Cup System, Pinnacle™ acetabular shell
- Where
- 8 sites in United States
- Volunteers
- 265 people
- Sponsor
- DePuy Orthopaedics
ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM)
FT839 in Autoimmune Diseases
The primary objectives of this trial are to evaluate the safety and tolerability and to determine the maximum tolerated dose (MTD) or recommended Phase 2 dose of FT839 with or without rituximab and/or background therapy and/or…
- Conditions
- ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM), Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE)
- Trial name
- NCT07800871
- Testing
- FT839
- Where
- United States
- Volunteers
- 446 people
- Sponsor
- Fate Therapeutics
Sepsis
Sepsis Multiomic Analysis & Risk sTratification in China
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, and delayed diagnosis remains a major driver of mortality, while traditional biomarkers (PCT, CRP, lactate) have limited early…
- Trial name
- China SMART-1 (NCT07599644)
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Yuebei People's Hospital
Prostate Cancer (Adenocarcinoma), Vitamin D on Tumor Response and Inflammatory Markers
Comparative Analysis of Immunological Responses to Vitamin D Replacement Therapy in Black and West African Men Diagnosed With Prostate Cancer: Elucidating Differential Effects on Immune Function Between Patients With Localized Disease and Those With Metastatic Progression
This study is testing whether fixing vitamin D deficiency in Black/West African men with prostate cancer can strengthen their immune system, improve quality of life, and even slow cancer progression compared to those who remain…
- Trial name
- iCCaRE (NCT07598032)
- Testing
- vitamin D 25(OH)D
- Where
- Nigeria
- Volunteers
- 200 people
- Sponsor
- University of Ilorin Teaching Hospital
Inflammatory Bowel Diseases, Ulcerative Colitis Chronic
Prevalence of Encephalopathy in Patients With Inflammatory Bowel Diseases
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are characterized by extraintestinal manifestations in approximately 30% of cases.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis Chronic, Crohn Disease, Irritable Bowel Syndrome
- Trial name
- PEIBD (NCT05519904)
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Endometritis, IVF
Mid-Infrared Spectroscopy as a Real Time Diagnostic Tool for Chronic Endometritis
The Investigator propose to develop an in-vitro technique for the measurement and analysis of freshly excised biopsies during hysteroscopy procedure in patients with suspected Chronic Endometritis (CE) condition.
- Trial name
- NCT04197167
- Testing
- Hysteroscopy, Infrared Spectroscopy
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hillel Yaffe Medical Center
Infection, Bacteremia
Pharmacodynamic Parameters of Two Different Doses of Cefepime
Pharmacokinetics is the study of the disposition of drugs in the body, while pharmacodynamics considers the interaction of the drug at the site of infection over time.
- Conditions
- Infection, Bacteremia, Pneumonia
- Trial name
- NCT00177736
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Pittsburgh
Crohn Disease
Nutritional Status and Body Composition of Adult Patients With Crohn's Disease
Patients with Crohn's disease generally have nutritional risks and malnutrition. The investigators will conduct a multicenter cross-sectional study to discover nutritional status and body composition of Chinese adult patients…
- Trial name
- NCT04915911
- Testing
- cross-sectional study
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)
Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER)
PREVENER is a randomized, open-label, multicenter, phase IV clinical trial designed to evaluate the efficacy and safety of a carotid ultrasound-based strategy for the primary prevention of cardiovascular events in patients with…
- Conditions
- Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Axial Spondy, Systemic Lupus Erythematosus (SLE)
- Trial name
- PREVENER (NCT07611747)
- Testing
- Carotid Ultrasound, High-intensity lipid-lowering therapy, Standard care according to ESC 2021 guidelines
- Where
- 17 sites in Spain
- Volunteers
- 1,944 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.