Clinical trials: Inflammatory Joint Disease
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Study of Families With Twins or Siblings Discordant for Rheumatic Disorders
This study will examine families in which one sibling of a sibling pair, or twin pair, has developed a systemic rheumatic disease and one has not, to see if and how the two differ in the following: Blood cell metabolism; Types of…
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies
- Trial name
- NCT00055055
- Where
- 3 sites in United States
- Volunteers
- 1,056 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Ankylosing Spondylitis
Post-authorization Safety Study of Etoricoxib and Other Anti-inflammatory Therapies in European Patients With Ankylosing Spondylitis (MK-0663-163)
This study is a population-based cohort of patients with ankylosing spondylitis (AS) from general medical practices in the UK, France, and Germany with a nested case control component to assess associations between drug exposures…
- Trial name
- NCT01077843
- Testing
- Etoricoxib, Other Cox-2 inhibitors, Other Non-selective NSAIDs
- Volunteers
- 27,381 people
- Sponsor
- Organon and Co
Rheumatoid Arthritis
Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA®) Treatment
This nationwide, multicenter, single arm, prospective, non-interventional study will evaluate the quantitative pattern of NSAID use and the impact of treatment with tocilizumab on NSAID use in a representative cohort of…
- Trial name
- CONIFER (NCT03112213)
- Testing
- Tocilizumab, NSAIDs
- Where
- 27 sites in Germany
- Volunteers
- 135 people
- Sponsor
- Hoffmann-La Roche
Moderate to Severe Active Axial Spondyloarthritis
Enbrel-Sulfasalazin-Early-Axial Spondyloarthritis (AS)
Efficacy - To assess efficacy of etanercept versus sulfasalazine when added to NSAIDs in patients with moderate to severe active early axial spondyloarthritis duration of ongoing axial symptoms of less than 5 years.
- Trial name
- NCT00844142
- Testing
- Etanercept 25mg, Sulfasalazine
- Where
- 9 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Spondyloarthropathy, Crohn Disease
The SpACE Study - Small Bowel Crohn's Disease and Spondyloarthropathies
Inflammatory bowel disease is clinically associated with spondylarthropathies in 5-15% of cases. Protocol colonoscopic assessment demonstrated asymptomatic inflammation characteristic of Crohn's disease in up to 1/3 of SpA…
- Trial name
- SpACE (NCT03064815)
- Testing
- Videocapsule endoscopy, colonoscopy, PROMETHEUS® IBD sgi Diagnostic™
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Rheumatoid Arthritis, Psoriatic Arthritis
WORK-ON Vocational Rehabilitation for People With Inflammatory Arthritis
People with chronic inflammatory arthritis (IA) (rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis), often have a reduced work ability. Up to 40% lose their job in the first years after diagnosis.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Axial Spondyloarthritis
- Trial name
- WORK-ON (NCT06299917)
- Testing
- WORK-ON
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- The Danish Center for Expertise in Rheumatology
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
A Clinical Investigation of the M2a- 38™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- 38™ Hip System
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis
- Trial name
- NCT00698503
- Volunteers
- 190 people
- Sponsor
- Biomet Orthopedics, LLC
Ankylosing Spondylitis
Platelet and Red Blood Cell Volume Indices as Inflammatory Biomarkers in Ankylosing Spondylitis
this study aims to determine the relatioships among the NLR ,PLR ,MLR ,red cell volume and platelet volume indices levels as biomarkers in ankylosing spondylitis.
- Trial name
- NCT05997108
- Testing
- CBC
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sohag University
Spondyloarthropathies
The Characterization of Small Bowel and Colonic Involvement in Patients With Seronegative Spondyloarthritides
Up to 60% of patients with Seronegative Spondyloarthritides have inflammation in the colon or ileum. This is usually asymptomatic, but in 5 to 10% of patients with SA, Frank IBD will develop.
- Trial name
- SPONDILENDO (NCT00768950)
- Testing
- Capsule endoscopy examination, Colonoscopy
- Where
- Romania
- Volunteers
- 65 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Rheumatoid Arthritis
The Effect of an Anti-inflammatory Diet in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease that affects 0.5-1% of the population and in which his remission is not always achieved, affecting physical and mental well-being and quality of life (QL).
- Trial name
- DAIAR (NCT05336513)
- Testing
- Diet Control, Diet anti-inflammatory
- Where
- Portugal
- Volunteers
- 26 people
- Sponsor
- Universidade Nova de Lisboa
Knee Osteoarthritis, Osteoarthritis
Blood Cell Ratios as Predictors of Response to Platelet-Rich Plasma in Knee Osteoarthritis
Intra-articular platelet-rich plasma (PRP) injection is a widely used treatment for knee osteoarthritis, but patients respond to it very differently and there is currently no simple, inexpensive way to predict who will benefit.
- Trial name
- PRP-NLR (NCT07617233)
- Where
- Cyprus
- Volunteers
- 120 people
- Sponsor
- Utku Gürhan
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
28mm Ceramic-on-Ceramic Total Hip Replacement Study
This study is intended to gather medium (0-5 years) and long-term (6-10 years) information regarding the performance and safety of the commercially available Ceramax™ Ceramic on Ceramic Total Hip System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-traumatic Arthritis
- Trial name
- COC28 (NCT01657435)
- Testing
- Ceramax Acetabular System
- Where
- 13 sites in United States, Canada
- Volunteers
- 185 people
- Sponsor
- DePuy Orthopaedics
Rheumatoid Arthritis (RA)
Integrated Care Approach for Rheumatoid Arthritis Patients
The goal of this study is to learn about the long-term effects of integrated care approach in persons over the age of 20 who take part in integrated care approach to treat their rheumatoid arthritis (RA).
- Trial name
- NCT06791980
- Testing
- ETLA
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Dalin Tzu Chi General Hospital
Inflammatory Arthritis
Allied Health in Rheumatology Triage Project
There is accumulating evidence that early treatment leads to better outcomes for patients with inflammatory arthritis (IA). Triage, which is the process of identifying the urgency of a patient's disease state efficiently and…
- Trial name
- AHRT (NCT02465879)
- Testing
- Therapist Triage
- Volunteers
- 295 people
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoarthritis, Knee
Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab (OKINADA)
This is a Canadian randomized, double-blind, placebo-controlled, multicenter study designed to evaluate the clinical efficacy and safety of adalimumab versus placebo when used to treat subjects with a diagnosis of osteoarthritis…
- Trial name
- OKINADA (NCT02471118)
- Testing
- Adalimumab 40 mg
- Where
- 7 sites in Canada
- Volunteers
- 62 people
- Sponsor
- CARE ARTHRITIS LTD.
Crohn Disease, Spondyloarthritis
Identification of Fecal Microbiota Biomarkers of Spondyloarthritis in Patients Suffering From Crohn's Disease.
The MICROSPA project aims to compare gut microbiota, serum cytokines, and PBMC of patients suffering from Crohn's disease (CD) associated or not to spondylarthritis (SpA).
- Trial name
- MICROSPA (NCT03983473)
- Testing
- Microbiota Sequencing
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Rheumatoid Arthritis, Osteoarthritis
Effect of Anti-inflammatory (ITIS) Diet in Rheumatoid Arthritis
to study the effect of anti-inflammatory diet on clinical and biological outcomes in rheumatoid arthritis
- Trial name
- NCT04999683
- Testing
- ITIS diet
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Diego
Spondyloarthritis
99mTc-rhAnnexin V-128 in Diagnosis of Spondyloarthritis
This single center, open-label, proof of concept (PoC) Phase II study aimed to assess the investigational imaging agent 99mTc-rhAnnexin V-128 in detecting spondyloarthritis (SpA) lesions.
- Trial name
- Annexin 03 (NCT03232580)
- Testing
- rhAnnexin V-128
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Advanced Accelerator Applications