Clinical trials: Inflammatory Marker
Postpartum Lumbopelvic Pain
Factors Associated With Disability in Postpartum Lumbopelvic Pain
Postpartum lumbopelvic pain may affect functional ability, daily activities, physical performance, psychological well-being, and health-related quality of life.
- Trial name
- NCT07809685
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Halic University
Polyneuropathy, Inflammatory Demyelinating, Chronic
Real-world Study of Treatment Outcomes in Chronic Inflammatory Demyelinating Polyneuropathy/Polyradiculoneuropathy (CIDP)
This study is an observational, ambispective, descriptive, non-interventional study of people with a chronic inflammatory demyelinating polyneuropathy/polyradiculoneuropathy (CIDP) diagnosis in the United States with residual…
- Trial name
- ORBIT-CIDP (NCT06968975)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sanofi
Healthy Volunteers
Effects of a Dietary Supplement on Lipoprotein Lipids and Inflammatory Markers
The goal of this study is to assess the effects of a dietary supplement on fasting lipoprotein lipids and a marker of inflammation in men and women with levels of low-density lipoprotein cholesterol above desirable levels.
- Trial name
- NCT03118583
- Testing
- 300 mg/day of dietary supplement containing carrageenan
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Non-muscle Invasive Bladder Cancer, Cystoscopy
Biomarkers of Recurrence and Progression in Non-muscle Invasive Bladder Cancer
Bladder cancer (BC) is one of the most common type of cancer globally. Due to its high incidence rate, high risk of recurrence and progression, and frequent cystoscopy surveillance, BC contributes to major healthcare costs across…
- Conditions
- Non-muscle Invasive Bladder Cancer, Cystoscopy, Recurrence, Progression
- Trial name
- NCT06235853
- Testing
- Blood serum: sUPAR, PAI-1, IL-8., Urine: IL-8, APOE, VEGF.
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Wroclaw Medical University
Postoperative Cognitive Decline, Biomarkers
Patients Experiences of Early Postoperative Cognition
The study has a mixed-methods design i.e. integration of qualitative and quantitative data within a single investigation. Participants included will be patients ≥60 years that are undergoing major elective joint replacement…
- Conditions
- Postoperative Cognitive Decline, Biomarkers, Postoperative Recovery, Joint Replacement Surgery
- Trial name
- COME (NCT05361460)
- Testing
- Cognitive decline
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Crp
CRP/Albumin Ratio as a Predictive Inflammatory Marker for Postoperative SIRS and/or Sepsis
The goal of this observational study is to determine the value of CRP/Albumin Ratio as an inflammatory marker for predicting the development of postoperative Systemic Inflammatory Response Syndrome and/or Sepsis in…
- Trial name
- NCT06050759
- Testing
- CRP and Albumin level in blood sample
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Septic Shock, Sepsis, Severe
As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR
The sepsis and septic shock remain major causes of child morbidity and mortality, despite the use of modern antibiotics and resuscitation therapies.
- Trial name
- suPAR (NCT04459572)
- Testing
- suPAR
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ege University
Acute Ischemic Stroke, Cerebrovascular Disorders
Brain, Blood And Clot or Tissue Registry And Collaboration
This is a prospective open enrollment biorepository to collect and evaluate blood and tissue collected during cerebrovascular procedures, which will then be used for the purposes of identifying biological markers, inflammatory…
- Trial name
- BACTRAC (NCT03153683)
- Testing
- Registry
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Justin Fraser
Chronic Obstructive Pulmonary Disease
Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD
This study will examine the inflammatory response to exercise encompassed as part of a standard pulmonary rehabilitation programme in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- CIMPRES-COPD (NCT02740686)
- Testing
- Sample collection
- Where
- 6 sites in United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Lincoln
Diabetic Macular Edema
A Study to Assess the Use of Artificial Intellignce to Predict Eye Treatment Changes in Adult Participants With Diabetic Macular Edema
This study is to assess the use of Artificial intellignce (AI) to predict eye treatment changes in adult participants with diabetic macular edema (DME).
- Trial name
- OPTIMAL-3 (NCT07604545)
- Sponsor
- AbbVie
Bacterial Infections, Bacteremia
Procalcitonin Level and Kinetics in Children With Bacterial Infections
The purposes of this study are: 1. To determine whether procalcitonin level at admission of pediatric patients with bacterial infections can be used as a marker for prediction of defervescence and hospitalization length 2.
- Conditions
- Bacterial Infections, Bacteremia, Meningitis, Urinary Tract Infection
- Trial name
- NCT00714402
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Shaare Zedek Medical Center
Idiopathic Inflammatory Myopathies
Application of Electrical Impedance Myography (EIM) as a Potential Biomarker of Idiopathic Inflammatory Myopathies
1. To assess changes in impedance parameters in Idiopathic Inflammatory Myopathies (IIMs). 2. To assess whether EIM parameters are reflective of disease severity, based on clinical outcome measures of IIMs.
- Trial name
- NCT03918356
- Testing
- electrical impedance myography, healthy control group
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Sepsis, Acute Infection
A Multicenter Prospective Observational Study to Derive and Verify the Performance of a Host-response Based Diagnostic Tool for Early Detection of Severe Infections.
The study is a multi-center, prospective, observational clinical study enrolling patients from at least 3 medical centers. Study population will include patients over the age of 18 years.
- Trial name
- NCT06665542
- Where
- 8 sites in United States, Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Systemic Sclerosis, Inflammatory Myopathies
Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory Myopathies
Systemic sclerosis and inflammatory myopathies, which sometimes combine (scleromyositis), have shared pathophysiological elements.
- Trial name
- SCLEROMYOMICS (NCT04917705)
- Testing
- Collection of biological samples
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Strasbourg, France
Septic Shock
Evaluation of the Prognostic Value of Immature Platelet Fraction
Sepsis is a public health issue responsible for six million deaths worldwide each year. It is one of the leading causes of admission and morbidity and mortality in critical care.
- Trial name
- IPSIS (NCT07039227)
- Where
- France
- Volunteers
- 196 people
- Sponsor
- University Hospital, Rouen
Liver Transplant Infection
Impact of a TDM-guided ECPA Program for Optimizing Pharmacodynamic Target Attainment of Continuous Infusion Beta-lactam-based Regimen
Previous studies have clearly demonstrated a significant impact of optimised antibiotic therapy based on a TDM-guided approach in reducing the clinical and microbiological failure rate and in improving the achievement of an…
- Trial name
- NCT06718517
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Sepsis, Severe Sepsis
Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's)
This is a randomized controlled trial comparing standard-of-care therapy of infections in critically ill patients with a procalcitonin-guided approach evaluating efficacy (antibiotics consumption) and safety (mortality).
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- SAPS (NCT01139489)
- Testing
- procalcitonin-guidance
- Where
- Netherlands
- Volunteers
- 1,575 people
- Sponsor
- Amsterdam UMC, location VUmc
Tuberculosis, Inflammation Biomarkers
Effects of Adjunct Omega-3 Long Chain Polyunsaturated Fatty Acids in Pulmonary Tuberculosis Patient: an Early Bactericidal Activity and Inflammatory Trial
The goal of this randomized controlled trial is to evaluate the early bactericidal activity, early inflammatory response, and safety of omega-3 long chain polyunsaturated fatty acid (n-3 PUFA) supplementation in adult patients…
- Conditions
- Tuberculosis, Inflammation Biomarkers, Liver Function Tests, Iron Status
- Trial name
- TREAT 3 (NCT07118059)
- Testing
- Omega-3 (EPA+DHA)
- Where
- South Africa
- Volunteers
- 40 people
- Sponsor
- North-West University, South Africa