Clinical trials: Influenza Immunisation
Influenza
Rapid Vaccination of Hard-To-Reach Populations
The purpose of this study is to develop and determine the effectiveness of a multi-level community participatory intervention designed to rapidly immunize hard-to-reach populations, including substance users, within disadvantaged…
- Trial name
- NCT00155974
- Testing
- Community-based vaccine outreach intervention
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- The New York Academy of Medicine
Pregnancy, Investigation or Care in A Nonpregnant Woman
Evaluate the Immunogenicity and Safety of the 2011-2012 Vaccine Against Seasonal Influenza on Pregnant Women
The hypothesis proposed in this study is that the 2011-2012 Seasonal Influenza Vaccine (including H3N2 and H1N1 subtypes of serotype A strain over the serotype B) administered to 15ug (without adjuvant) via intramuscular in…
- Trial name
- VACINFL2011 (NCT01577316)
- Testing
- Seasonal influenza vaccination
- Where
- Mexico
- Volunteers
- 240 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Heart Failure, Influenza Vaccination
Sequential Digital Intervention to Increase Influenza Vaccination in Patients With Heart Failure
Influenza vaccination is an important preventive measure for patients with heart failure (HF), but vaccination uptake remains low in China.
- Trial name
- PANDA-BOOST (NCT07880158)
- Testing
- Routine Influenza Vaccination Recommendation, Repeated AI-Assisted Telephone Intervention, Gain-Framed SMS Reminder
- Where
- China
- Volunteers
- 588 people
- Sponsor
- Heart Health Research Center
Influenza Vaccine
Effect of a Multi-strain Probiotic Formulation on Immune Response to Influenza Vaccination
Randomized clinical trial to determine whether a probiotic formulation containing 4 probiotic strains which belong to Lactiplantibacillus plantarum and Pediococcus acidilactici species can boost the immune response to influenza…
- Trial name
- FLUVAC21 (NCT05157425)
- Testing
- Food Supplement
- Where
- 5 sites in Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Influenza, Influenza-like Illness
Adjuvanted Influenza Vaccination in U.S. Nursing Homes
This study is powered to prospectively evaluate the relative effectiveness of adjuvanted trivalent influenza vaccine (aTIV; FLUAD) in preventing influenza mortality, hospitalization, and functional decline in a nursing home…
- Trial name
- NCT02882100
- Testing
- adjuvanted trivalent influenza vaccine, trivalent influenza vaccine
- Where
- United States
- Volunteers
- 823 people
- Sponsor
- Insight Therapeutics, LLC
Influenza
A Study to Evaluate the Safety and Immune Responses to Fluzone® Vaccination
To describe the safety of the inactivated, split-virion influenza vaccine, 2008-2009 formulation. To evaluate the compliance, in terms of immunogenicity, of the inactivated, split-virion influenza vaccine 2008-2009 formulation…
- Trial name
- NCT00743275
- Testing
- Split, Inactivated, Trivalent Influenza vaccine (Fluzone®)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Influenza Immunization
Substudy 01 - Safety and Immunogenicity of One Monovalent Modified mRNA Vaccine Encoding Influenza Hemagglutinin With LNP, in Adult Participants Aged 18 to 49 Years and 60 Years and Above
This is a Phase 1, parallel, randomized, active-controlled, multi-center, dose-esclation study with a Master Protocol design which will include several substudies that are developed to evaluate the safety and immunogenicity of…
- Trial name
- NCT05829356
- Testing
- H3 mRNA / LNP Vaccine, Quadrivalent recombinant influenza Vaccine (RIV4)
- Where
- 8 sites in Australia, United Kingdom
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Influenza
Pediatric Safety and Immunogenicity Study of Cell-Culture Derived and Egg-based Subunit Influenza Vaccines in Healthy Children and Adolescents
The present study is the first study designed to evaluate safety, tolerability and immunogenicity of the cell culture-derived influenza vaccine in healthy children and adolescents aged 3 to 17 years.
- Trial name
- NCT00645411
- Testing
- Cell culture-derived influenza subunit vaccine (cTIV), Egg derived influenza subunit vaccine (eTIV)
- Where
- 60 sites in United States, Croatia and 5 more
- Volunteers
- 3,604 people, healthy volunteers welcome
- Sponsor
- Novartis
Arsenic--Toxicology, Immunologic Disorders Complicating Pregnancy
Pregnancy, Arsenic and Immune Response
As the global availability of vaccines increases, and reaches areas disproportionately affected by arsenic and malnutrition, resolving questions about potential environmental and biologic barriers to maternal immunization has…
- Conditions
- Arsenic--Toxicology, Immunologic Disorders Complicating Pregnancy, Vaccine Response Impaired, Micronutrient Deficiency
- Trial name
- PAIR (NCT03930017)
- Testing
- Seasonal influenza vaccine - VAXIGRIP TETRA influenza vaccine (quadrivalent, split virion, inactivated)
- Where
- Bangladesh
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type 1 Diabetes Mellitus
Adherence to Guidelines VAccination in Type 1 DIabetes Mellitus Patients (AVADI-1).
Observational study about adherence to guidelines for Influenza, Pneumococcal and Hepatitis B Vaccination in adult patients with type 1 Diabetes mellitus.
- Trial name
- AVADI-1 (NCT03478254)
- Testing
- Influenza vaccination, Pneumococcal vaccination, Hepatitis B Virus (HBV) vaccination
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Jesús Moreno Fernández
Influenza
Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities
While the COVID-19 pandemic has highlighted health disparities, Black children have unduly suffered and died from seasonal influenza for decades.
- Trial name
- NCT06274359
- Testing
- Digital storytelling
- Where
- 2 sites in United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Influenza
Immunogenicity Trial of Recombinant Influenza Vaccine Among HCP in Israel
This randomized, open-label, active-controlled trial will assess humoral immune responses to a single dose of 2019-20 recombinant hemagglutinin quadrivalent influenza vaccines (RIV4) compared with standard egg-based unadjuvanted…
- Trial name
- NCT04523324
- Testing
- Flublok™ Quadrivalent by Sanofi, Inc., VaxigripTetra™ by Sanofi, Inc.
- Where
- 2 sites in Israel
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Influenza Immunization, Healthy Volunteers
Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2020-2021 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively
Primary Objective: To provide serum samples (collected from participants before vaccination [Blood Sample 1] and after final vaccination [Blood Sample 2]) to Center for Biologics Evaluation and Research (CBER) for further…
- Trial name
- NCT04551677
- Testing
- Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2020-2021 formulation, Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2020-2021 formulation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Influenza
Proteomic Profiling for Influenza
The purpose of this study is to evaluate a new method of detecting the flu infection. This method may allow researchers to identify new proteins being made in response to an infection even before symptoms of the infection are…
- Trial name
- NCT00133588
- Testing
- Trivalent split Inf
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Influenza
Assessment of Efficacy of CR8020 and CR6261, Monoclonal Antibodies, Against Influenza Infection
The purpose of this study is to evaluate the rate of decline in quantitative viral load measured in hospitalized patients with Influenza A infection
- Trial name
- NCT01992276
- Testing
- CR8020, CR6261
- Where
- 68 sites in United States, Australia and 10 more
- Sponsor
- Crucell Holland BV
Rheumatoid Arthritis, Influenza
2-week dc of MTX and Influenza Vaccination in RA
To investigate whether a transient discontinuation of methotrexate MTX for 2 weeks improves the vaccination response to a seasonal influenza.
- Conditions
- Rheumatoid Arthritis, Influenza, Methotrexate
- Trial name
- 2 wk MTX (NCT02897011)
- Testing
- Methotrexate
- Where
- 3 sites in South Korea
- Volunteers
- 318 people
- Sponsor
- Seoul National University Hospital
Infectious Disease by Haemophilus Influenzae Type b
Immunogenicity and Safety Study of 4th LBVH0101 After the Primary Vaccination in LG-VHCL002 Study
This is a multi-center, comparative, two-arm, parallel-group, single-blind, phase III study to assess immunogenicity and safety of 4th LBVH0101 (Haemophilus influenzae type b tetanus toxoid conjugate vaccine) vaccination compared…
- Trial name
- NCT01251133
- Testing
- LBVH0101 (Hib vaccine), Hiberix™ Vaccine
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- LG Life Sciences
Influenza
Safety and Immunogenicity Study of Intramuscular CCS/C-adjuvanted Influenza Vaccine in Elderly
To examine the safety and immunogenicity of two formulation of liposomal adjuvant / delivery system (VaxiSomeTM=CCS-Cholesterol [CCS/C]), combined with commercial influenza vaccine in an elderly healthy population when given once…
- Trial name
- NCT00915187
- Testing
- CCS/C, Influenza Vaccine
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- NasVax Ltd
Acute Myocardial Infarction, Cardiovascular Diseases
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
The goal of this randomized, double-blind, placebo-controlled clinical trial is to investigate the immunological effects of influenza vaccination outside of the influenza season on arterial inflammation in patients with a recent…
- Conditions
- Acute Myocardial Infarction, Cardiovascular Diseases, Inflammatory Response
- Trial name
- ELIMINATE (NCT06336317)
- Testing
- Influenza vaccine
- Where
- 3 sites in Denmark, Sweden and 1 more
- Volunteers
- 90 people
- Sponsor
- Region Örebro County
Influenza and Pneumonia
Study on Combined Vaccination With Quadrivalent Influenza Vaccine and 23-valent Pneumococcal Polysaccharide Vaccine
This study is an open-label,single center phase Ⅳ clinical trial of combined immunization with quadrivalent influenza vaccine and 23-valent pneumococcal polysaccharide vaccine.The purpose of this study is to evaluate the safety…
- Trial name
- NCT05471531
- Testing
- Combined vaccination with quadrivalent influenza vaccine and 23-valent pneumococcal polysaccharide vaccine, Separate vaccination with quadrivalent influenza vaccine and 23-valent pneumococcal polysaccharide vaccine
- Where
- 4 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd