Clinical trials: Inguinal Hernioplasty
Hernia, Inguinal
Mesh Fixation and Closure of Peritoneum Following Laparoscopic Hernia Repair Using N-butyl Cyanoacrylate
Fixation of mesh and peritoneal closure during TAPP repair using n-butyl cyanoacrylate.
- Trial name
- NCT02457728
- Testing
- LiquiBandFix8
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna
Ultrasound, Transversalis Fascia Plane Block
Ultrasound-Guided Transversalis Fascia Plane Block Versus Caudal Block for Postoperative Analgesia in Children Undergoing Inguinal Herniorrhaphy
The aim of this study is to compare ultrasound-guided transversalis fascia plane block and caudal block for postoperative analgesia in children undergoing inguinal herniorrhaphy.
- Conditions
- Ultrasound, Transversalis Fascia Plane Block, Caudal Block, Postoperative Analgesia
- Trial name
- NCT06725667
- Testing
- Transversalis fascia plane block, Caudal block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Postsurgical Pain Management
Phase 2/3 Study of TLC590 for Postsurgical Pain Management
A phase 2/3 randomized, double-blind, 2-part, comparator- and placebo-controlled study to assess the safety, pharmacokinetics and efficacy of postsurgical local infiltration in adult subjects following inguinal hernia repair…
- Trial name
- NCT05161637
- Testing
- TLC590, Bupivacain, Ropivacaine
- Volunteers
- 415 people
- Sponsor
- Taiwan Liposome Company
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Pain Management, Mtapa Block
M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery
Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room.
- Conditions
- Pain Management, Mtapa Block, TAP Block
- Trial name
- pain (NCT07311902)
- Testing
- TAP Block Group, M TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Inguinal Hernia, Postoperative Pain
Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain
The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.
- Trial name
- NCT01450345
- Testing
- Pregabalin
- Where
- Malaysia
- Volunteers
- 72 people
- Sponsor
- University of Malaya
Hernia, Inguinal
Day-case or Inpatient Care Following Inguinal Hernia Repair in Elderly Patients
The aim of the study was to evaluate the feasibility of day surgery for elderly patients undergoing elective open inguinal hernia repair.
- Trial name
- NCT01041430
- Testing
- day surgery group, inpatient group
- Where
- Finland
- Volunteers
- 89 people
- Sponsor
- Helsinki University Central Hospital
Hernia, Recurrence
Laparoscopic Groin Hernia Repair by a 3D ENDOLAP Visible Mesh With or Without LiquiBand Fix 8 Mesh Fixation
This study aims to visualize the implanted mesh in vivo by MRI in 20 patients at 1 month and 12 months post-operatively. Moreover, we want to evaluate the safety and efficiency of non-penetration mesh fixation techniques using…
- Trial name
- NCT02781870
- Testing
- LiquiBand Fix8 glue fixation, No-fixation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hernia, Inguinal, Laparoscopy
Transabdominal Preperitoneal Inguinal Hernia Repair
The present study seeks to determine whether improved visual acuity and enhanced flexibility of the robotic platform results in a reduced surgical stress response and an improvement in indices of surgical outcome measures for…
- Trial name
- TAPP (NCT05839587)
- Testing
- Robotic TAPP, Laparoscopic TAPP
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Chronic Pain Following Surgical Procedure for Cancer
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group)…
- Trial name
- NCT04700592
- Testing
- Gabapentin versus Ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Inguinal Hernia Unilateral, Postoperative Pain
Quadro-Iliac Plane Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia Repair
The goal of this randomized controlled trial is to learn whether an ultrasound-guided quadro-iliac plane block (QIPB) reduces opioid use and pain after laparoscopic inguinal hernia repair in adults aged 18-65 years.
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain, Opioid Use
- Trial name
- QIPB-LIHR (NCT07878936)
- Testing
- Quadro-iliac plane block
- Volunteers
- 64 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Emergence Delirium, Anesthesia
Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in Children
This is a clinical study for comparing the efficacy of two drugs i.e propofol and dexmedetomidine in prevention of a group of post operative abnormal behaviours that can occur after sevoflurane anesthesia in children and we will…
- Trial name
- NCT07799311
- Testing
- propofol 1mg/kg, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Post Operative Pain
Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Analgesia in Inguinal Hernia Repair
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
- Trial name
- NCT05565365
- Testing
- Transversalis fascia plane (TFP) block, Erector Spinae Plane (ESP) Block
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Assiut University
Inguinal Hernia Without Obstruction or Gangrene
Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair
The current study aims to determine whether a use of closed suction drain following laparoscopic inguinal hernia surgery performed for an inguinoscrotal variety can decrease the incidence of symptomatic seroma formation requiring…
- Trial name
- SALHS (NCT03563092)
- Testing
- Laparoscopic Inguinal Hernia (TEP/TAPP) Surgery
- Where
- India
- Volunteers
- 100 people
- Sponsor
- GEM Hospital & Research Center
Inguinal Hernia, Postoperative Pain
Lumbar ESP Block Versus TAP Block for Postoperative Pain Control in Children Undergoing Open Inguinal Hernia Repair
This study evaluates two ultrasound-guided nerve block techniques-Erector Spinae Plane Block (ESPB) and Transversus Abdominis Plane (TAP) block-for pain relief in children undergoing elective open inguinal hernia repair.
- Trial name
- NCT07916233
- Testing
- Ultrasound-guided Lumbar Erector Spinae Plane Block (ESPB), Ultrasound-guided Transversus Abdominis Plane (TAP) Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Primary Inguinal Hernia, Unilateral Hernia
The Efficacy of a Self-fixating Mesh in Unilateral Open Inguinal Hernia Repair
This study's objective is to assess the efficacy of a Self-fixating mesh in the surgical repair of unilateral inguinal hernia, which is becoming the new standard of care in open surgical repair of inguinal hernia.
- Conditions
- Primary Inguinal Hernia, Unilateral Hernia, Open Surgery
- Trial name
- NCT01596049
- Testing
- Self-fixating Mesh
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Rambam Health Care Campus
Inguinal Hernia, Pain, Postoperative
Ilioinguinal-iliohypogastric Nerve Block Prior to Shouldice Inguinal Hernia Repair
The introduction of ilioinguinal-iliohypogastric nerve blocks into the preoperative care regimen at Shouldice Hospital for inguinal hernia repair marks a significant shift in pain management strategies.
- Trial name
- NBSS (NCT06314815)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Shouldice Hospital
Inguinal Hernia
Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years
Laparoscopic techniques have been applied widely to the management of various common pediatric surgical diseases. Current evidence lacks sufficient quality to justify the widespread adoption of the laparoscopic approach to the…
- Trial name
- NCT00716768
- Testing
- Laparoscopic Inguinal Hernia Repair, Open Inguinal Hernia Repair
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Post Operative Pain, Inguinal Hernia
Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study
Many patients undergoing inguinal hernia repair are prone to developing acute and chronic post-operative pain. The aim of the study is to show a possible correlation between pain and acute phase proteins in order to: predict the…
- Trial name
- NCT06380140
- Testing
- Open Tension-free Inguinal Hernia Repair
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- University of Roma La Sapienza
Postoperative Pain
Caudal Block for Inguinal Hernioplasty in Children
This is a prospective, randomized, controlled clinical study designed to determine the effectiveness of caudal block combined with general anesthesia in providing intra- and postoperative analgesia, and its effect on hemodynamic…
- Trial name
- NCT05958589
- Testing
- Caudal block with levobupivacaine, General anesthesia, Inguinal hernioplasty
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- University of Novi Sad