Clinical trials: Inguinal Hernioplasty
Inguinal Hernia Bilateral
Laparoscopic vs Open Bilateral Inguinal Hernia Repair
The European Hernia Society Guidelines of 2018 suggest that laparoscopic surgery should be preferred over open surgery for bilateral inguinal hernia repair even though scientific evidence are scarce.
- Trial name
- NCT04679116
- Testing
- Laparoscopic bilateral inguinal hernia repair, Open bilateral inguinal hernia repair
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- General Hospital of Larissa
Inguinal Hernia Repair, Mesh Infection
Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis
Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required.
- Trial name
- NCT07491250
- Testing
- Complete mesh removal, Partial mesh removal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fudan University
Postoperative Pain
Spinal Versus General Anesthesia for Transabdominal Preperitoneal (TAPP) Repair of Inguinal Hernia
The purpose of the study is to assess whether spinal anesthesia is superior to the standard general anesthesia or not for patients undergoing transabdominal preperitoneal inguinal hernia repair (TAPP).
- Trial name
- NCT01520857
- Testing
- Transabdominal Preperitoneal repair of inguinal hernia
- Where
- Greece
- Volunteers
- 140 people
- Sponsor
- Larissa University Hospital
Inguinal Hernia, Chronic Pain
Chronic Pain After Inguinal Hernia Repair
Chronic pain after inguinal hernia repair has become a major concern. Although tension-free Lichtenstein technique is used and new lightweight meshes have been developed, still up to 40 % of patients complain of some kind of pain…
- Trial name
- GRIP-ME (NCT00820131)
- Testing
- selfgrip mesh, lightweight mesh with suture fixation
- Where
- 7 sites in Austria
- Volunteers
- 250 people
- Sponsor
- Medical University of Vienna
Inguinal Hernia Bilateral
Inguinal Hernia Repair and Male Fertility
General objective: To evaluate the fertility of adult men submitted to bilateral herniorrhaphy with mesh placement by the Lichtenstein and laparoscopic approaches
- Trial name
- NCT05799742
- Testing
- Bilateral hernioplasty
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hernia, Hernia Abdominal Wall
Image-Guided Herniorrhaphy Study
This pilot clinical study will evaluate the safety and effectiveness of a new image-guided, needle-based approach for repairing abdominal or groin hernias in adults who are unable or unwilling to undergo traditional open or…
- Conditions
- Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia
- Trial name
- NCT07267494
- Testing
- Image-Guided Herniorrhaphy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Pain, Postoperative
Efficacy of Adding Dexmedetomidine as an Adjuvant to Bupivacaine in TAP Block and Caudal Block
This study compares the efficacy of Dexmedetomidine as an adjuvant to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block versus Caudal Block for post-operative analgesia in children undergoing congenital inguinal…
- Trial name
- NCT04926454
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
Comparison of Oral Zaldiar With Intravenous Paracetamol and Tramadol
Comparison of two different regimens of analgesia after inguinal hernia repair. First, is a classical intravenous protocol with paracetamol and tramadol.
- Trial name
- NCT02389361
- Testing
- Zaldiar, Paracetamol-Tramadol
- Volunteers
- 51 people
- Sponsor
- Astes
Inguinal Hernia
Randomized Multicentre Study Comparing TEP With Lichtenstein Repair for Primary Inguinal Hernia
The purpose of this study was to compare the recurrence rate after TEP (laparoscopic method) and Lichtenstein (open method) repair on primary inguinal hernia.
- Trial name
- NCT00568269
- Testing
- Open repair, Laparoscopic repair
- Where
- Sweden
- Volunteers
- 1,513 people
- Sponsor
- Uppsala University Hospital
Hernia, Inguinal
Efficacy of Macroporous Polytetrafluoroethylene Mesh in Laparoscopic Hernia Repair
Inguinal hernia repair is one of the most commonly performed surgeries around the world. It accounts for approximately 75% of all abdominal wall hernias and presents a lifetime risk of 27% in males and 3% in females.
- Trial name
- PTFE (NCT02023203)
- Testing
- Totally Extraperitoneal laparoscopic inguinal hernia repair
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Unilateral Inguinal Hernia
Tizanidine and Pain After Herniorrhaphy
Herniorrhaphy is the most frequent general surgical procedure. There are moderate pain complaints after herniorrhaphy. Besides causing discomfort to the patients, pain, can delay recovery and discharge and cause cognitive…
- Trial name
- NCT02016443
- Testing
- Tizanidine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Diskapi Teaching and Research Hospital
Hernia, Anesthetics Adverse Reaction
Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial
This present randomized trial is designed to evaluate the postoperative pain,inflammatory marker, postoperative analgesic medication, length of hospital stay and the modifications of inflammatory mediators in patients undergoing…
- Conditions
- Hernia, Anesthetics Adverse Reaction, Inflammation
- Trial name
- NCT01845376
- Testing
- local anesthesia group, spinal anesthesia group, general anesthesia group
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Mingkwan Wongyingsinn, MD
Postoperative Pain
Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair
Multimodal analgesia is used to control postoperative pain in inguinal hernia repair. Transversus abdominis plane block is an effective regional anesthesia technique for postoperative analgesia in inguinal hernia repairs.
- Trial name
- NCT03515434
- Testing
- ESP Block, TAP Block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Chronic Groin Pain, Hernia, Inguinal
Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair
This study is evaluating the management of chronic post-operative inguinal hernia pain and the impact of hernia mesh removal after previous minimally invasive inguinal hernia repairs.
- Trial name
- NCT05484635
- Testing
- Diagnostic laparoscopy and inguinal mesh removal, Diagnostic laparoscopy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- David Krpata
Hernia, Ventral Hernia
Prospective Clinical Evaluation of High-Purity Type I Collagen in Select High-Risk Hernia Repair Scenarios
This prospective, single-arm clinical study evaluates the safety, feasibility, and early clinical outcomes of High-Purity Type I Collagen (HPTC; Surgicoll-Mesh®) when used as a biologic reinforcement in selected hernia repair…
- Conditions
- Hernia, Ventral Hernia, Incisional Hernia, İnguinal Hernia
- Trial name
- NCT07360691
- Testing
- High-Purity Type I Collagen Mesh
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Sevoflurane Agitiion in Pediatric
Comparing the Synergistic Effect of Caudal Dexmedetomidine and Propofol Versus Caudal Dexmedetomidine Only or Propofol Only in Prevention of Sevoflurane Related Emergence Agitation in Pediatric Patients Undergoing Congenital Inguinal Hernia Repair
evaluate the synergistic efficacy of propofol and caudal dexmedetomidine for postoperative EA in pediatrics aged from to 2 to 5 years maintained on sevoflurane inhalational anesthesia and scheduled for conginital inguinal hernia…
- Trial name
- NCT06734195
- Testing
- dexmedetomidine + propofol, Propofol alone, Dexmedetomidine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Inguinal Hernia
Safety and Performance Study of TIGR Matrix Surgical Mesh in Inguinal Hernia Repair
This an open, uncontrolled multicenter clinical study to assess the safety and performance of the WK-6 surgical mesh in adult patients with unilateral inguinal hernia.
- Trial name
- NCT01193985
- Testing
- TIGR Matrix Surgical Mesh
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Novus Scientific
Analgesia
Extended Delivery of Bupivacaine Study in Herniorrhaphy
This is a phase 4, randomized, open-label study of the efficacy, safety, and pharmacokinetics of bupivacaine administered as liposomal bupivacaine or continuous infusion via elastomeric pump following unilateral open inguinal…
- Trial name
- NCT04102267
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine HCl without epinephrine via continuous infusion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics