Clinical trials: Inhalation
Chronic Low-back Pain
Breathing and Attention Training for Chronic Low Back Pain
The purpose of this research study is to see if breathing and attention training (BAT) treatments improve pain symptoms and well-being in people who have chronic low back pain (cLBP).
- Trial name
- NCT04740710
- Testing
- Breathing and Attention Training
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Florida
Healthy
The Influence of Exercise and Hydration to the Pharmacological Response to Inhaled Terbutalin and Salbutamol in Men
To investigate the effects of dehydration and exercise for the urine secretion of beta2-agonists.
- Trial name
- NCT05749523
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vibeke Backer
Irritable Bowel Syndrome, Healthy Subjects
Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction
Patients with disorders of gut-brain interaction (DGBI) often present gastrointestinal symptoms that do not show noticeable irregularities in standard examinations.
- Conditions
- Irritable Bowel Syndrome, Healthy Subjects, Functional Gastrointestinal Disorders, Laryngopharyngeal Reflux
- Trial name
- NCT06205446
- Testing
- Healthy subjects : abdominal breathing, Laryngopharyngeal reflux disease subjects : abdominal breathing, Dyspepsia subjects : abdominal breathing
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Pulmonary Disease, Chronic Obstructive
Study Investigating Repeat Doses Of A New Medication (GSK159797) In Asthmatic Patients
This study is designed to determine the efficacy and safety of a new long-acting beta-agonist for asthma patients (GSK159797) following dosing for 14 days.
- Trial name
- NCT00358488
- Testing
- GSK159797 (10, 15, and 20mcg), salbutamol, salmeterol 50mcg
- Where
- 6 sites in Germany, Netherlands and 3 more
- Volunteers
- 54 people
- Sponsor
- GlaxoSmithKline
Deep Breathing Maneuver, PROGRESSIVE MUSCLE RELAXATION EXERCISES
SHORT-TERM EFFECTS OF DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES ON MUSCULOSKELETAL PAIN AND WELL-BEING IN HIGH SCHOOL STUDENTS
Exam stress in high school students, long hours of studying in the static posture, and lack of physical activity habits can cause physical and psychological discomfort in them.
- Trial name
- Deep breathing (NCT06972173)
- Testing
- DEEP BREATHING AND PROGRESSIVE MUSCLE RELAXATION EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Pulmonary Mucormycosis
Efficacy and Safety of Systematic Therapy and Bronchoscopic Interventional Treatment for Pulmonary Mucormycosis
Evaluation of the effectiveness and safety of transbronchoscopic local precision infusion of amphotericin B + transoral nebulized inhalation of amphotericin B + transbronchoscopic interventional debridement + liposomal…
- Trial name
- NCT06495905
- Testing
- transbronchoscopic interventional debridement
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Asthma
Efficacy of LAMA Added to ICS in Treatment of Asthma (ELITRA)
Primary objective The primary objective was to evaluate the superiority of CHF 5259 (glycopyrronium bromide [GB]) in a pressurised metered dose inhaler (pMDI) (50 μg total daily dose) versus placebo in terms of forced expiratory…
- Trial name
- ELITRA (NCT02296411)
- Testing
- CHF 5259 12.5 µg + Qvar
- Where
- 28 sites in Bulgaria, Germany and 3 more
- Volunteers
- 98 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Major Depressive Disorder
Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation
This study characterized the impact of respiratory-gated transcutaneous vagus nerve stimulation (tVNS) on the modulation of the stress response circuitry, vagal tone and depressed mood in patients with major depressive disorder…
- Trial name
- tVNS-MDD (NCT04467164)
- Testing
- exhalatory-gated transcutaneous vagus nerve stimulation (e-RAVANS), Inhalatory-gated transcutaneous vagus nerve stimulation (i-RAVANS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive
Safety, Toleration and Efficacy of Single Inhaled Doses of PF-00610355 in Chronic Obstructive Pulmonary (COPD) Patients.
This study will look at the pharmacokinetics, safety, toleration and efficacy of PF-00610355 in the chronic obstructive pulmonary disease (COPD) population.
- Trial name
- A7881010 (NCT00783406)
- Testing
- PF-00610355
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
Nemiralisib is a potent anti-inflammatory agent for the treatment of chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
- Trial name
- NCT03398421
- Testing
- Nemiralisib, Itraconazole
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Exercise Training, Apnea
Breathing Protocol in Breath-hold Divers
The aim of this randomized controlled trial study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Apnea, Breathholding, Breathing Exercises
- Trial name
- NCT04366414
- Testing
- hook breathing removing nose-clip, usual breathing (UB)
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Safety, Pharmacokinetics
To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594
The purpose of this study is to evaluate the safety profile and look at levels of AZD7594 and biomarkers in blood when the drug is administered inhaled to healthy subjects
- Conditions
- Safety, Pharmacokinetics, Pharmacodynamics of AZD7594
- Trial name
- NCT01636024
- Testing
- AZD7594
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma
Efficacy of Ciclesonide During the Cold Season in Patients Older Than 12 Years With Persistent Asthma
The aim of the study is to evaluate the efficacy of ciclesonide in patients with persistent asthma over 3 months, especially in the cold season. Ciclesonide will be inhaled by a metered-dose inhaler.
- Trial name
- ARTIST (NCT00608218)
- Testing
- Ciclesonide
- Where
- 153 sites in Germany
- Volunteers
- 2,100 people
- Sponsor
- AstraZeneca
Chronic Leg Ulcer
Efficacy of 50% Nitrous Oxide/50% Oxygen Gas Premix in Chronic Leg Ulcer Debridement
Adequate analgesia in serial chronic leg ulcer debridement can be difficult to achieve. A common analgesia method is the topical administration of local anesthetics directly onto the wound.
- Trial name
- NCT02696460
- Testing
- N2O/O2 analgesia, Lidocaine/Prilocaine analgesia
- Volunteers
- 21 people
- Sponsor
- Venenklinik Bellevue
Pulmonary Disease, Chronic Obstructive
Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)
The primary objective of this study is to determine the optimum dose(s) of BI 1744 CL administered with 5 micrograms tiotropium bromide solution for inhalation, delivered by the Respimat inhaler, once daily for four weeks in…
- Trial name
- NCT00696020
- Testing
- BI 1744 CL/tiotropium bromide fixed dose combination, tiotropium bromide, Respimat® Inhaler
- Where
- 37 sites in United States, Canada and 1 more
- Volunteers
- 360 people
- Sponsor
- Boehringer Ingelheim
Respiratory Insufficiency
Non-invasive Measurements of Elastance and Resistance
The study aims to assess the agreement between respiratory mechanics parameters measured noninvasively by means of brief airways occlusions at the beginning of inspiration and the reference parameters obtained with standard…
- Trial name
- ERNI (NCT01530282)
- Testing
- Invasive method, Non invasive method
- Volunteers
- 15 people
- Sponsor
- University of Turin, Italy
Renal Transplantation
Muscle Oxygenation, Functional Capacity and Frailty in Kidney Transplant Recipients with and Without Inspiratory Muscle Weakness
The aim of this study was to compare respiratory function, muscle oxygenation, functional capacity, peripheral muscle strength, body composition, and frailty in kidney transplant recipients with and without inspiratory muscle…
- Trial name
- NCT06706492
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-3
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01045811
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Heart Failure, Fatigue
The Effect of Breathing Exercise on Fatigue in Heart Failure Patients
In this study, It is aimed to evaluate the effect of breathing exercise on fatigue in patients with heart failure, to reduce the severity of fatigue in participants, and thus to enable patients to participate more actively in…
- Trial name
- NCT05129371
- Testing
- Breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Mustafa Kemal University
Upper Abdominal Surgery
Compare the Effect of Incentive Spirometry Versus Chest Mobilization on Oxygenation and Chest Expansion for Patient Undergoing Upper Abdominal Surgery: A Randomized Clinical Trial
This study compares the effects of incentive spirometry and chest mobilization on oxygenation and chest expansion in patients after upper abdominal surgery.
- Trial name
- NCT07109934
- Testing
- deep breathing exercises, chest mobilization:
- Where
- Iraq
- Volunteers
- 112 people
- Sponsor
- Marwa karim jabr
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