Clinical trials: Inhalation
Oxygen Inhalation Therapy, Second Stage of Labour
Maternal Oxygen Administration for Fetal Distress
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Second Stage of Labour, Fetal Distress
- Trial name
- NCT02221440
- Testing
- Low flow nasal oxygen, Low flow room air
- Where
- 3 sites in China
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Nitrous Oxide, Dentistry
Demand-Driven Method for Gas Delivery in a Dental Setting
This study compares two methods of gas delivery in a dental setting: 1) demand-driven (DD) and 2) free-flow (FF). Nitrous oxide and oxygen sedation (NOS) is a common form of minimal sedation for adult and paediatric patients…
- Conditions
- Nitrous Oxide, Dentistry, Drug Delivery System, Comfort
- Trial name
- NCT04305990
- Testing
- Demand-driven delivery method, Free-flow delivery method
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Inhalation Injury, Pulmonary Disease
The Effect of a Pulmonary Rehabilitation on Lung Function and Exercise Capacity in Patients With Burn
Inhalation burn injury and lung complications caused by large surface burns occurring during a fire remains a serious problem. Pulmonary rehabilitation has been used successfully to improve pulmonary function(PF) in patients with…
- Trial name
- NCT04125108
- Testing
- pulmonary rehabilitation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Hangang Sacred Heart Hospital
Anxiety State, Pediatric ALL
Anxiolytic Effects of Lavender and Orange Oil
The aim of this study is to determine the possible anxiety reducing effects of lavender oil and orange oil on parents with children receiving dental care under sedation during perioperative wait.
- Conditions
- Anxiety State, Pediatric ALL, Dental Anxiety, Oil; Inhalation
- Trial name
- NCT04079309
- Testing
- Lavender/Orange
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Analgesic Adverse Reaction, Nociceptive Pain
The Correlation Between Sevoflurane and qNOX
This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.
- Conditions
- Analgesic Adverse Reaction, Nociceptive Pain, Inhalation; Vapor
- Trial name
- NCT03665792
- Testing
- nociception index qNOX
- Where
- China
- Volunteers
- 58 people
- Sponsor
- China International Neuroscience Institution
Smoke Inhalation Injury, Burns
Critical Smoke Alarm Characteristics to Awaken Children From Stage 4 Sleep
Specific Aim 1 is to test the hypothesis that there are specific characteristics of a voice smoke alarm (i.e., use of child's first name, behavior commands in the message content, use of mother's voice, and stimulus frequency)…
- Trial name
- NCT01169155
- Testing
- Smoke Alarm Stimuli
- Where
- United States
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Breast Augmentation, Inhalation Anesthesia
Effects of General Anesthesia on Quality of Recovery After Transaxillary Endoscopic Breast Augmentation
Among aesthetic or cosmetic surgeries, breast augmentation was the most frequently performed and the endoscopic transaxillary approach has become the preferred incision for Asian women.
- Conditions
- Breast Augmentation, Inhalation Anesthesia, Total Intravenous Anesthesia, Quality of Recovery
- Trial name
- NCT04036487
- Testing
- Desflurane, Propofol
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Chih-Cheng Hung
Burns, Smoke Inhalation Injury
Helping Children's Centres to Enhance Home Safety
Many children have accidents, some are very serious and they are a major cause of death in children aged 1-4 years. Many accidents are preventable This study aims to find out the best way to help Children's Centres to provide…
- Trial name
- NCT01452191
- Testing
- Injury Prevention Briefing Plus facilitation, Injury Prevention Briefing
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Smoke Inhalation
Electronic Cigarette and Surgery (ECigarSurg)
Since decades, literature has shown that smoking has negative effect on postoperative outcome. Recent systematic review and meta-analysis on clinical impact of smoking and smoking cessation showed that postoperative healing…
- Trial name
- ECigarSurg (NCT03594643)
- Where
- France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Exercise Therapy, Physical Activity
HOPE (Home-based Oxygen [Portable] and Exercise) for Patients on Long Term Oxygen Therapy (LTOT)
Long term oxygen therapy (LTOT) is proven to increase the survival of patients with respiratory failure, most commonly from diseases such as Chronic Obstructive Pulmonary Disease (COPD).
- Conditions
- Exercise Therapy, Physical Activity, Respiratory Failure, Oxygen Inhalation Therapy
- Trial name
- HOPE (NCT03662438)
- Testing
- Home-based physiotherapy program, Prescription of a Portable Oxygen Concentrator (POC) device
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore General Hospital
Inhalational Anthrax
Safety, Tolerability and PK of Repeat Administration of Intravenous ETI-204 in Adult Volunteers
To evaluate the safety, tolerability, pharmacokinetics and immunogenicity of repeat administration (two doses) of intravenous (IV) ETI-204.
- Trial name
- NCT01932242
- Testing
- ETI-204
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Inhalational Anthrax
Intramuscular Dose-Escalation Study With ETI-204 in Adult Volunteers
This study is to evaluate the safety, local tolerability, pharmacokinetics (PK) and immunogenicity of escalating single intramuscular (IM) doses of ETI-204 in healthy volunteers
- Trial name
- NCT01932437
- Testing
- ETI-204
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Inhalational Anthrax
Safety, Tolerability and PK of Intravenous (IV) ETI-204 Alone and in Presence of Ciprofloxacin in Adult Volunteers
Evaluate the safety, tolerability and pharmacokinetics (PK) of intravenous (IV) ETI-204 alone and in the presence of IV and oral ciprofloxacin
- Trial name
- NCT01952444
- Testing
- ETI-204, Ciprofloxacin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Inhalational Anthrax
Safety, Tolerability, and PK of a Single Intravenous Dose of ETI-204 in Adult Volunteers
To evaluate the safety and tolerability and pharmacokinetics (PK) of a single intravenous (IV) dose of ETI-204 in adult volunteers.
- Trial name
- NCT01929226
- Testing
- ETI-204
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Elusys Therapeutics
Smoke Inhalation Patients
Impact of Hydroxocobalamine on Outcome of Smoke Inhalation Injury Admitted to the ICU
In Europe, hydroxocobalamin (cyanokit) has been used for suspicion of cyanide intoxication associated with the inhalation of fire smoke (1). However, the impact of hydroxocobalamin on outcome has never been thoroughly evaluated.
- Trial name
- COB-AKI (NCT03558646)
- Testing
- There is no intervention planned (observational)
- Where
- France
- Volunteers
- 739 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Airway Extubation, Oxygen Inhalation Therapy
High Flow Nasal Cannula in Immediately Post Extubation
The aim of the study is to determine the incidence of failure of extubation in high-risk patients using High Flow Nasal Cannula (HFNC) to prevent such failure in the Intensive Care Unit. A prospective cohort study was performed.
- Trial name
- HFNC (NCT03495947)
- Testing
- high flow nasal cannula
- Where
- Argentina
- Volunteers
- 165 people
- Sponsor
- Hospital Italiano de Buenos Aires
Smoke Inhalation Injury, Morality
Smoke Inhalation Injury in Patients Admitted to Intensive Care
Many Studies have shown that the smoke-inhalation injury is responsible for a high mortality mainly related to the systemic effects of carbon monoxide and cyanide.
- Trial name
- fumeintox (NCT03834246)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Therapeutic Treatment of Inhalation Anthrax
An Open-label, Nonrandomized Study to Evaluate the Safety and Immunogenicity of Raxibacumab With Reinjection
This is an open-label study to evaluate the immunogenicity and safety of raxibacumab in healthy adult male and female subjects. Subjects who have received raxibacumab >= 4 months ago will be enrolled and dosed as follows: A…
- Trial name
- NCT02016963
- Testing
- Raxibacumab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Human Genome Sciences Inc.
Inhalation Anesthesia
Comparison of Midazolam or Dexmedetomidine on Epileptiform EEG During Sevoflurane Mask Induction
Induction with high sevoflurane concentrations may trigger epileptiform electroencephalographic activity without motor or cardiovascular manifestations in healthy patients.
- Trial name
- NCT03394430
- Testing
- Midazolam, Dexmedetomidine
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Vasovagal Syncope, Smoke Inhalation
Relation Between Vasovagal Tendency and Smoking Among University Students
Almost everyone is aware these days is aware about the risk of smoking. Still many people start this habit specially in early life and during college year.
- Trial name
- NCT02949804
- Testing
- Comparison between two groups
- Where
- Jordan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jordan Collaborating Cardiology Group