Clinical trials: Inhalation
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of a Mask Seal/Mask for the Treatment of Obstructive Sleep Apnea (OSA)
This investigation is designed to evaluate the performance as well as the patients overall acceptance of the seal/mask.
- Trial name
- NCT03092921
- Testing
- F&P Mask Seal, F&P Mask
- Where
- New Zealand
- Volunteers
- 18 people
- Sponsor
- Fisher and Paykel Healthcare
Asthma
A Study to Evaluate the Effect of Repeat Doses of GW870086X in Mild to Moderate Asthmatics
This study will measure the effect of repeat inhaled doses of GW870086X on lung function.
- Trial name
- NCT00945932
- Testing
- GW870086X
- Where
- 8 sites in Germany
- Volunteers
- 37 people
- Sponsor
- GlaxoSmithKline
Myotonic Dystrophy
Sleep Breathing Disorders, a Main Trigger for Cardiac ARythmias in Type I Myotonic Dystrophy ?
Up to one-third of patients with myotonic dystrophy type 1 die suddenly mainly from arrhythmias. Sleep apnea is prevalent in myotonic dystrophy (DM1) patients.
- Trial name
- STAR (NCT02375087)
- Where
- France
- Volunteers
- 73 people
- Sponsor
- University Hospital, Grenoble
Difficult Breathing
Accuracy of Ultrasound in Identification of Cricothyroid Membrane: A Randomized Clinical Trial
Routine surgery requires artificial breathing through the placement of a plastic tube into the patient's windpipe via mouth or nose. This tube serves as the source of providing oxygen to the patients during surgery.
- Trial name
- NCT01725828
- Testing
- Ultrasound, External Palpation
- Where
- 2 sites in Canada
- Volunteers
- 223 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Analgesic Adverse Reaction, Nociceptive Pain
The Correlation Between Sevoflurane and qNOX
This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.
- Conditions
- Analgesic Adverse Reaction, Nociceptive Pain, Inhalation; Vapor
- Trial name
- NCT03665792
- Testing
- nociception index qNOX
- Where
- China
- Volunteers
- 58 people
- Sponsor
- China International Neuroscience Institution
Coronavirus
Trial of Alpha One Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
It is clear now that SARS-CoV-2 could use angiotensin-converting enzyme 2 (ACE2), the same receptor as SARS-CoV Transmembrane protease serine type 2 (TMPRSS2), a protease belonging to the type II transmembrane serine protease…
- Trial name
- NCT04385836
- Testing
- alpha one antitrypsin inhalation
- Where
- Saudi Arabia
- Volunteers
- 150 people
- Sponsor
- Ministry of Health, Saudi Arabia
COPD, IPF
Inhaled NO in IPF and COPD During 6 Minute Walk Test
Our objective is to evaluate the influence of inhaled NO on the saturation and exercise capacity of patients with COPD and IPF. each participant will undergo two six minute walk tests, one with inhaled NO and the other with…
- Conditions
- COPD, IPF, Inhaled Nitric Oxide, Six Minute Walk Test
- Trial name
- NCT03873298
- Testing
- Inhaled nitric oxide
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
High Flow Nasal Cannula, Respiratory Insufficiency
Weaning Protocol for High Flow Nasal Cannula Oxygen Therapy
High flow nasal cannula oxygen therapy has been widely used in critically ill patients. Despite effectiveness of high flow nasal cannula as a treatment, optimal methods to withdrawal high flow nasal cannula after recovery from…
- Trial name
- SLOWH (NCT03845244)
- Testing
- Flow reduction first, FiO2 reduction first, Simultaneous (flow and FiO2) reduction
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Obesity Hypoventilation Syndrome (OHS)
Average Volume-assured Pressure Support as Rescue Therapy in Obesity Hypoventilation Syndrome
It remains unclear whether CPAP therapy should be prescribed if significant hypoxemia persists during CPAP titration, despite optimization of upper airway obstructive events, if maximum CPAP pressure is reached.
- Trial name
- AVAPS (NCT06442163)
- Testing
- AVAPS study was performed within 1 week of the CPAP titration attempt failure, using the auto-titrating EPAP (AE), the OmniLab Advanced +, System One device (Philips Respironics, Murrysville, PA, U.S.
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Dyspnea, Cardiopulmonary Dysfunction
Effect of Different Breathing Techniques on Dyspnea and Cardiopulmonary Parameters Among Patients After Open Heart Surgery
Open heart surgery is often associated with postoperative pulmonary complications, reduced lung expansion, dyspnea, and impaired cardiopulmonary function.
- Conditions
- Dyspnea, Cardiopulmonary Dysfunction, Postoperative Respiratory Dysfunction, Coronary Artery Disease
- Trial name
- NCT07591987
- Testing
- Segmental Breathing Exercises, Active Cycle Breathing Technique, Standard postoperative care
- Where
- 3 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Intraoral Tumor
Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane.
- Trial name
- PSIOS (NCT06275087)
- Testing
- Propofol, Sevoflurane
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Clinical Hospital Centre Zagreb
Breathing, Mind-body Practices
Study to Measure Relaxation From Different Types of Focused Breathing Exercises
Mind-body practices, such as yoga, ta'i chi, mindfulness and biofeedback, commonly use slow breathing techniques to induce physiological and mental relaxation.
- Conditions
- Breathing, Mind-body Practices, Yoga, Meditation
- Trial name
- NCT02226744
- Testing
- Focused Breathing
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Bronchopulmonary Dysplasia
Early Predictors of Bronchopulmonary Dysplasia in Extremely Preterm Infants
Bronchopulmonary dysplasia (BPD) remains one of the most common complications in extremely preterm infants despite advances in neonatal intensive care.
- Trial name
- EPIRESP (NCT07771387)
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Asthma
SOLO-Symbicort® in the Treatment of Persistent Asthma in Adolescents & Adults
The purpose of this study is to compare Symbicort Single Inhaler treatment with the Best Conventional Practice in patients with persistent asthma
- Trial name
- NCT00238784
- Testing
- Budesonide/formoterol Turbuhaler
- Where
- 3 sites in Canada
- Volunteers
- 1,300 people
- Sponsor
- AstraZeneca
Cystic Fibrosis
Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642)
The purpose of this study is to obtain data on the potential of long-term treatment with denufosol to improve the clinical course of CF lung disease in patients with mildly impaired lung function and to provide CF patients who…
- Trial name
- DEFY (NCT00846781)
- Testing
- Denufosol tetrasodium Inhalation Solution
- Volunteers
- 308 people
- Sponsor
- Merck Sharp & Dohme LLC
COPD
A Single-dose Study to Investigate the Effects of 3 Different Doses of Inhaled AZD2115 in COPD Patients
This study in COPD patients will investigate the bronchodilatory effect of AZD2115. AZD2115 will be tested versus placebo and active comparators.
- Trial name
- NCT01498081
- Testing
- AZD2115, Indacaterol, Indacaterol + Tiotropium
- Where
- 6 sites in Poland, Sweden
- Volunteers
- 39 people
- Sponsor
- AstraZeneca
Body Temperature, Oxygen Saturation
Clinical Evaluation of the Vital Signs Monitoring System (VSMS)
This is an observational, cohort-based, single-site, prospective study conducted in accordance with ISO 14155-1:2003 and ISO 14155-1:2011.
- Conditions
- Body Temperature, Oxygen Saturation, Respiration, ECG
- Trial name
- NCT03206528
- Testing
- Vital Signs Monitoring System
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- G Medical Innovations Ltd.
Asthma
Optimization of Inhaled Corticosteroid Treatment in Adult Patients With Asthma Guided by Exhaled NO Measurement at Home
To compare the clinical outcome (effectiveness) of single inhaled corticosteroid (ICS) controller treatment guided by exhaled NO measurement made at home with usual care asthma management with regard to asthma control (primary…
- Trial name
- OCTAGEN (NCT01783132)
- Testing
- NIOX MINO
- Where
- Sweden
- Volunteers
- 142 people
- Sponsor
- Orion Corporation, Orion Pharma
Healthy Volunteers
Comparison of 30 Units of TI (Technosphere® Insulin) Prepared With Insulin From Two Different Suppliers
A Phase 1, open-label randomized crossover trial in Healthy Volunteers to evaluate the PK/PD of TI (Technosphere® Insulin) prepared with insulin from two different suppliers.
- Trial name
- NCT01982604
- Testing
- TI-Inhalation Powder A, TI-Inhalation Powder B
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Low Back Pain, Mechanical, Low Back Pain, Chronic
Effects of Foundation and Functional Inspiratory Muscle Training in Non-Specific Chronic Low Back Pain
This study was planned to examine the effects of basic and functional respiratory muscle training on pain, disability level, and functionality. In this study, participants will be randomly divided into 3 groups.
- Conditions
- Low Back Pain, Mechanical, Low Back Pain, Chronic, Non Specific Chronic Low Back Pain
- Trial name
- NCT06696300
- Testing
- Classical Physiotherapy Group, Foundation Inspiratory Muscle Training in Addition to Classical Physiotherapy, Functional Inspiratory Muscle Training Group in Addition to Classical Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
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