Clinical trials: Inhalation Injury
Depressive Disorder, Major, Post Traumatic Stress Disorder
A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans
The proposed study addresses a gap regarding the need for effective Major Depressive Disorder (MDD) treatments and the 40% of individuals treated with antidepressant medications that do not achieve full remission.
- Trial name
- NCT03489122
- Testing
- yoga, walking
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- VA Office of Research and Development
Pulmonary Hypertension, Bronchopulmonary Dysplasia
Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia
Inhaled nitric oxide (iNO) is an effective treatment for pulmonary hypertension (PH) in term and near-term infants. Preterm infants are at risk for early PH that is associated with high risk for bronchopulmonary dysplasia or…
- Trial name
- NCT03576885
- Testing
- inhaled nitric oxide
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- AdventHealth
Bronchopulmonary Dysplasia, Very Low Birth Weight
Preterm Infant Inhaled Albuterol Dosing
The purpose of this study is to help determine the best dose of inhaled albuterol sulfate in premature babies at risk of developing bronchopulmonary dysplasia (BPD).
- Trial name
- NCT02447250
- Testing
- Varied albuterol dose response
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Stress Disorders, Post-Traumatic
Breathing Meditation Intervention for Post Traumatic Stress Disorder
Post traumatic stress disorder (PTSD) is a condition that develops as a result of exposure to a traumatic event. The purpose of this study is to determine whether a breathing meditation technique (Sudarshan Kriya Yoga; SKY)…
- Trial name
- NCT02366403
- Testing
- SKY meditation, CPT-C
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Sleep-disordered Breathing
Treatment of Sleep-disordered Breathing in Patients With SCI
Sleep-disordered breathing (SDB) remains under-treated in individuals living with spinal cord injuries and disorders (SCI/D). The investigators' aim is to test a program that addresses challenges and barriers to positive airway…
- Conditions
- Spinal Cord Injury, Sleep-disordered Breathing, Spinal Cord Disease, Multiple Sclerosis
- Trial name
- NCT02830074
- Testing
- Best practices PAP + patient Education +ongoing Support and Training, Sleep Education
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- VA Office of Research and Development
Apnea, Sleep, Chronic Fatigue Syndrome
Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
The purpose of this study is to determine any sleep disordered breathing in veterans with Gulf War Syndrome (GWS) and compare it to healthy normal asymptomatic Gulf War veterans.
- Trial name
- NCT00252629
- Testing
- Nasal CPAP treatment during sleep
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- US Department of Veterans Affairs
Traumatic Brain Injury
Inhaled Nitric Oxide in Brain Injury
This study will evaluate the changes in respiratory mechanics following traumatic brain injury and determine the effect of inhaled nitric oxide on gas exchange.
- Trial name
- NCT03260569
- Testing
- Inhaled Nitric Oxide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Cincinnati
Spinal Cord Injuries, Pneumonia
Inspiratory Strength and Respiratory Complications After SCI Injury
The investigators conducting this study to investigate the relation between the respiratory muscle strength and respiratory complications.
- Trial name
- RESCOM (NCT02891096)
- Testing
- inspiratory muscle strength
- Where
- Switzerland
- Volunteers
- 550 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Bronchopulmonary Dysplasia
Examining the Use of Non-Invasive Inhaled Nitric Oxide to Reduce Chronic Lung Disease in Premature Newborns
Bronchopulmonary dysplasia (BPD) is a serious lung condition that affects premature newborns. The condition involves abnormal development of lung tissue and is characterized by inflammation and scarring in the lungs.
- Trial name
- NCT00955487
- Testing
- Inhaled Nitric Oxide (iNO)
- Where
- 6 sites in United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Prematurity, Bronchopulmonary Dysplasia
Inhaled Nitric Oxide and Neuroprotection in Premature Infants
The purpose of this study is to determine whether inhaled nitric oxide improves the neurological outcome for premature infants.
- Conditions
- Prematurity, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Periventricular Leukomalacia
- Trial name
- NOVA2 (NCT00515281)
- Testing
- inhaled nitric oxide, oxygen
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- University of Chicago
Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide
The purpose of this study is to determine if the combination of late doses of Infasurf with inhaled nitric oxide will interact to improve the surfactant function and thus the respiratory status and outcome of treated infants.
- Trial name
- TOLSURFPilot (NCT00569530)
- Testing
- Infasurf (ONY Inc.)
- Where
- 9 sites in United States
- Volunteers
- 85 people
- Sponsor
- Roberta Ballard
Acute Lung Injury, Acute Respiratory Distress Syndrome
Airway Pressure Release Ventilation in Acute Lung Injury
The purpose of this study is to compare airway pressure release ventilation (APRV) to conventional mechanical ventilation (MV) in patients with acute lung injury (ALI) to determine if APRV can reduce agitation, delirium, and…
- Conditions
- Acute Lung Injury, Acute Respiratory Distress Syndrome, Mechanical Ventilation
- Trial name
- NCT00750204
- Testing
- APRV, Conventional MV
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Inhalation Injury, Pneumonitis
Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
The investigators hypothesize that the scheduled use of bronchoscopy on a regular basis after inhalation injury in burn patients will improve outcome by providing pulmonary hygiene, decrease the incidence of pneumonia, and detect…
- Conditions
- Inhalation Injury, Pneumonitis, Pneumonia
- Trial name
- NCT00997555
- Testing
- bronchoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Hurley Medical Center
Spinal Cord Injuries, Sleep Disordered Breathing
Role of Mirtazapine in Ameliorating Sleep Disordered Breathing
The purpose of this study is to look at the effect of using Mirtazapine to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury (SCI)…
- Trial name
- NCT04799782
- Testing
- Mirtazapine
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Organic Brain Syndrome, Nonpsychotic, Neurocognitive Disorders
Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome
The investigators have designed an innovative proof-of-concept trial designed to provide data as to whether the treatment/rehabilitation efficacy and functional outcome of patients with organic brain syndrome are improved with…
- Conditions
- Organic Brain Syndrome, Nonpsychotic, Neurocognitive Disorders, Mental Disorder, Organic, Delirium, Dementia, Amnestic, Cognitive Disorders
- Trial name
- NCT02957123
- Testing
- Intranasal auto-M2-BFs
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Russian Academy of Medical Sciences
Brain Injuries, Traumatic
Noninvasive Neuromodulation for Treatment of Symptoms Due to Mild or Moderate Traumatic Brain Injury
The investigators hypothesis is that electrical stimulation to the tongue that directly stimulates two cranial nerve nuclei (Trigeminal and Facial Nerve Nuclei), will excite neural impulses to the brainstem and cerebellum.
- Trial name
- NCT02158494
- Testing
- Balance and Gait Training using neurostimulation modulation.
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Wisconsin, Madison
Reperfusion Injury, Liver Injury
Study to Evaluate if Inhaled Nitric Oxide Improves Liver Function After Transplantation
This blinded, placebo-controlled study will administer inhaled nitric oxide to patients undergoing liver transplantation. The purpose of the study is to test if inhaled nitric oxide prevents liver injury associated with the…
- Trial name
- NCT00582010
- Testing
- inhaled nitric oxide, nitrogen gas
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham