Clinical trials: Inhalation Therapy; Complications
Infant, Newborn, Hypertension, Pulmonary
Inhaled Nitric Oxide Study for Respiratory Failure in Newborns
Respiratory failure in term newborns is associated with increased rates of death and long-term neurodevelopmental problems. This large international multicenter trial randomized newborns who had failed to respond to intensive…
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration
- Trial name
- NINOS (NCT00005776)
- Testing
- Inhaled nitric oxide
- Where
- 20 sites in United States, Canada
- Volunteers
- 235 people
- Sponsor
- NICHD Neonatal Research Network
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients
Patients requiring prolonged time on the ventilator are susceptible to a wide range of clinical complications and excess mortality. It is therefore imperative for them to wean at the earliest possible time.
- Conditions
- Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation, Muscle Weakness
- Trial name
- NCT03453944
- Testing
- VentFree prototype (VF03-K) active stimulation
- Where
- 3 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Nijmegen
Cancer, Lung Resection
The PRIMROSE Trial
Smoking is a major cause for developing lung cancer. People diagnosed with lung cancer, may be offered surgery which offers a complete cure.
- Conditions
- Cancer, Lung Resection, Inspiratory Muscle Training, Prehabilitation
- Trial name
- PRIMROSE (NCT07365072)
- Testing
- Inspiratory muscle training (POWERBreathe), Standard Prehab
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Swansea Bay University Health Board
Respiratory Insufficiency, Ventilation Therapy; Complications
KAP Asynchrony Survey
The investigators developed a web-based survey to assess knowledge, attitudes and practice of health care professionals about patient-ventilator asynchrony.
- Conditions
- Respiratory Insufficiency, Ventilation Therapy; Complications, Ventilators, Mechanical, Respiration, Artificial
- Trial name
- KAPA (NCT03439683)
- Testing
- Survey about patient-ventilator asynchrony
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Postpartum Hemorrhage
Postpartum Oxygen Inhalation for the Treatment of Postpartum Haemorrhage
In the aetiology of postpartum uterine atony, hypoxia is considered an important factor although some suggest that peripheral oxygen saturation is not influenced by oxygen inhalation in women during the first and second stages of…
- Trial name
- NCT01180192
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Diabetic Peripheral Neuropathic Pain
A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The primary purpose of this study is to evaluate the safety and efficacy of medical cannabis aerosol containing 0.25, 0.50, 1.0 milligrams (mg) delta (Δ) 9-tetrahydrocannabinol (THC) inhaled three times a day (TID) compared to…
- Trial name
- NCT06490445
- Testing
- Medical Cannabis
- Where
- 38 sites in Australia, Czechia and 3 more
- Volunteers
- 122 people
- Sponsor
- Syqe Medical
Spinal Cord Injuries (SCI), Urinary Retention
Clinical Trial of Abdominal Breathing for Urinary Retention After Spinal Cord Injury
Randomized controlled trials were conducted in patients with urinary retention after spinal cord injury. The effects of abdominal breathing training on pelvic floor muscle tone, muscle strength and residual urine volume in…
- Trial name
- NCT06964256
- Testing
- Abdominal breathing exercises, Control group: intermittent catheterization, Experimental group: intermittent catheterization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Respiration; Insufficient or Poor, Newborn, Infant,Premature
Comparison of Leakage With Nasal Prongs and Nasal Mask Interface in Newborns Receiving CPAP Treatment
The study is a two-armed randomized cross-over comparison of leakage with nasal prongs and nasal mask interface in newborn infants treated with CPAP, born after 28 weeks of gestational age.
- Trial name
- ToNIL (NCT03586856)
- Testing
- Nasal mask interface, Nasal prongs interface
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Baldvin Jonsson
Respiratory Distress Syndrome, Ventilation Therapy; Complications
Changes in Lung Aeration and Inspiratory Effort With and Without Awake Prone
The investigators aimed to investigate the ventilation homogeneity and transpulmonary pressure during treatments of High-flow nasal cannula(HFNC) and (CPAP) on supine and prone position for COVID-19 or non-COVID-19 patients with…
- Trial name
- NCT05719103
- Testing
- With and Without Awake Prone Positioning
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Shanghai Zhongshan Hospital
Kidney Diseases
Effects of Virtual Reality and Breathing Exercises on Hemodialysis Patients' Symptoms and Quality of Life
Purpose: This study aims to examine the effects of virtual reality glasses and breathing exercises on symptoms and quality of life in patients receiving hemodialysis treatment.
- Trial name
- NCT06968130
- Testing
- routine hemodialysis, Breathing Exercise, Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Trakya University
Postoperative Atelectasis, Postoperative Hypoxemia
REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)
The purpose of this study is to determine if the frequency of use of incentive spirometry during the stay in the Post-Anesthesia Care Unit (PACU) increases with visual and auditory electronic reminders, as compared to not having…
- Conditions
- Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications
- Trial name
- NCT06304493
- Testing
- Alarms
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- University of Colorado, Denver
Sleep Disorder; Breathing-Related, Cardiovascular Diseases
Minimally Invasive Detection of a Sleep Apnoea
Obstructive sleep apnoea (OSA) is characterised by recurrent nocturnal respiratory interruptions, resulting from the total or partial collapse of the upper respiratory ways.
- Conditions
- Sleep Disorder; Breathing-Related, Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Complication
- Trial name
- KCG_SLEEP (NCT03760159)
- Testing
- Kinocardiography unintrusive recording
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Inhalation Therapy; Complications
The Effect of Watching Informative Animation on Fear and Anxiety in Children
The aim of this project was to determine the effect of showing informative animations to children on anxiety and fear during inhalation therapy. This project is a randomized controlled trial.
- Trial name
- NCT05861232
- Testing
- Behavioral
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mukader Kaya