Clinical trials: Inhibition, Psychological
Hypoactive Sexual Desire Disorder
Lybridos in Pre-and Postmenopausal Women With Hypoactive Sexual Desire Disorder
A double-blind, randomized, placebo-controlled, dose-finding study to investigate the safety and efficacy of Lybridos in the domestic setting in healthy female subjects with hypoactive sexual desire disorder and maladaptive…
- Trial name
- NCT02101203
- Testing
- 0.5 mgTestosterone + 10 mg Buspirone
- Where
- 10 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emotional Brain NY Inc.
Pulmonary Arterial Hypertension
The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
The purpose of this study is to find out if spironolactone added to ambrisentan for Pulmonary Arterial Hypertension (PAH) will increase exercise capacity.
- Trial name
- NCT02253394
- Testing
- Ambrisentan plus Spironolactone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Alcohol Dependence
Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study
The main aim of this research is to investigate whether the use of cognitive event-related potentials is an interesting way to identify subgroups of alcoholic patients displaying specific clinical symptoms and cognitive…
- Trial name
- NCT02107352
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Brugmann University Hospital
Stroke, Rehabilitation
Comprehensive Intensive Stroke Rehabilitation
In this study, the investigators aim to assess the effectiveness of the Comprehensive Intensive Rehabilitation Program After Stroke implementing the International Classification of Functioning, Disability and Health model, and to…
- Conditions
- Stroke, Rehabilitation, Physical Therapy Modalities
- Trial name
- COMIRESTROKE (NCT05323916)
- Testing
- Neuroproprioceptive "facilitation, inhibition", Technology based physical therapy, Effectively managed rehabilitation implementing the recommendations of the World Health Organization
- Where
- Czechia
- Volunteers
- 280 people
- Sponsor
- Charles University, Czech Republic
Healthy
Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study
The purpose of this study is to characterize the acute psychological, physiological, endocrine, and pharmacokinetic, as well as long-term psychological effects of LSD in humans.
- Trial name
- NCT01878942
- Testing
- LSD
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Exercise, Smartphone Addiction
The Effects of 8-week Resistance and Aerobic Exercise on Anxiety, Depression, Sleep, Inhibitory Control in Young Adults With Smartphone Overdependence
The purpose of this study is to identify the effects of the resistance exercise and aerobic exercise on depression, anxiety, sleep, inhibitory control in young adult with smartphone overdependence
- Conditions
- Exercise, Smartphone Addiction, Sleep, Inhibition
- Trial name
- NCT06848322
- Testing
- resistance exercise, aerobic exercise
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- University of Seoul
Impulsive Behavior, Inhibition
Inhibition Transcranial Random Noise Stimulation
Inhibition control deficits is a major risk factor in the transition to the act in suicidal patients. Neuroimaging studies have shown that this failure was associated with hypoactivity in the prefrontal cortex (PFC), a brain area…
- Trial name
- inhibistim (NCT02717260)
- Testing
- transcranial random noise stimulation (tRNS) (Starstim)
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Alcohol Dependence
The Approach and Avoidance Task (AAT) in Alcoholic Inpatients
The approach and avoidance task (AAT) has evolved as a promising treatment add-on in the realm of psychology. Certain psychiatric diseases, such as behavioural addictions, social anxiety disorder, and arachnophobia, are…
- Trial name
- NCT04054336
- Testing
- Inhibit AAT, classical AAT, Control Group
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pathological Gambling
Impulsivity in Pathological Gambling
The purpose of the this study is to compare pathological gamblers versus non-pathological gamblers using tests that measure different components of impulsivity.
- Trial name
- NCT00580567
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Total Knee Arthroplasty, Osteoarthritis
Electrical Stimulation After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is performed more than 300,000 times a year in the United States, most often for osteoarthritis (OA).
- Trial name
- NCT00224913
- Testing
- Neuromuscular electrical stimulation, Voluntary exercise
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Tinnitus, Hearing Loss
Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss
Tinnitus, the perception of sound in the absence of an external acoustic stimulus. Tinnitus is often perceived inside the head rather than the ear and is a common condition with a prevalence estimated between 10 and 15% in…
- Trial name
- IGNITE (NCT04862572)
- Testing
- MRI scanning
- Where
- 3 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Dyslexia, Executive Dysfunction
The Effects of Play and Competition-Based Cognitive Therapy
Purpose: The aim of this study was to investigate the effects of play and competition-based cognitive therapy (PCB-CT) on executive function and occupational routines in children with dyslexia.
- Trial name
- NCT03906097
- Testing
- Play and Competition-Based Cognitive Therapy
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Anxiety Mild to Moderate, Inhibition (Psychology)
Tiny Heroes Compared to Treatment as Usual to Decrease and Prevent Anxiety Problems in Young Children - a Randomized Controlled Study
The aim of this randomized controlled trial is to evaluate the effectiveness and cost-effectiveness of Tiny Heroes, a parent-directed internet-delivered cognitive behavioral therapy (iCBT) program for anxiety problems in children…
- Trial name
- NCT07870213
- Testing
- Parent-directed online cognitive behavioral therapy, Treatment as Usual (TAU)
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Alcohol Use Disorder
Severe Alcohol-use Disorder: a tDCS and Response Inhibition Training Intervention
Most severe forms of alcohol-use disorder are thought to reflect an abnormal interplay between two neural systems: an overly active impulsive one driven by immediate rewards prospects and a weak reflective one, tuned on long-term…
- Trial name
- ALCOSTIM (NCT03447054)
- Testing
- Combined TDCS active and ICT active, Combined TDCS active and ICT inactive
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Brugmann University Hospital
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Atherosclerotic Cardiovascular Disease
REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification
The Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification (REVEAL) trial aims to determine whether lipid modification with anacetrapib 100mg daily reduces the risk of coronary death, myocardial infarction…
- Trial name
- REVEAL (NCT01252953)
- Testing
- Anacetrapib
- Where
- United Kingdom
- Volunteers
- 30,449 people
- Sponsor
- University of Oxford
Feeding Behavior, Inhibition (Psychology)
Specificity of Flavor-Nutrient Learning: An fMRI Experiment
This is an etiology study designed to examine the how people's brains and behaviors respond to regularly consuming a beverage. Participants are assessed at 2 behavioral assessments (Wave 1 and Wave 2), 2 scans (at the BRIC), and…
- Trial name
- NCT02624206
- Testing
- Juice A, Juice B
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tic Disorders
Neuromodulation of Inhibitory Control in Tic Disorders
The present study aims to assess the effects of non invasive electrical stimulation of the vagus nerve via transcutaneous vagus nerve stimulation (tVNS) on cognitive functions, inhibitory and tic control in patients with tic…
- Trial name
- NCT05263414
- Testing
- tVNS
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Peripheral Nerve Sheath Tumor
Tazemetostat in Malignant Peripheral Nerve Sheath Tumors
This phase 2, open label, single arm study will investigate the use of tazemetostat in patients with recurrent/refractory and/or metastatic malignant peripheral nerve sheath tumors.
- Trial name
- NCT04917042
- Testing
- Tazemetostat
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida