Clinical trials: Inhibitory Control
Lactation Suppressed, Second Trimester Abortion
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age.
- Trial name
- NCT06123026
- Testing
- Cabergoline
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Mechanical Neck Pain
Effects of Autogenic and Reciprocal Inhibition Techniques With Conventional Therapy in Mechanical Neck Pain
The objective of this randomized control trial is to determine the effectiveness of Autogenic and Reciprocal Inhibition techniques with conventional therapy in mechanical neck pain to improve Pain, Range of Motion, and Functional…
- Trial name
- NCT05044078
- Testing
- Autogenic Inhibition MET, Reciprocal Inhibition MET
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Attention Deficit Hyperactivity Disorder (ADHD)
Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
The investigators are conducting this randomized trial to determine if IBBS (Integrated Brain, Body, and Social)intervention is an effective treatment for ADHD (attention Deficit Hyperactivity Disorder) in two culturally distinct…
- Trial name
- IBBS (NCT01542528)
- Testing
- IBBS
- Where
- 5 sites in United States, China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Yale University
Anaerobic Performance
Psychophysical Aspects of Maximal Anaerobic Performance
During anaerobic exercise, the metabolic pathway of glycolysis is used in order to produces high-energy compounds adenosine triphosphate (ATP).The level of lactic acid in the blood is a marker to the increased protons…
- Trial name
- NCT01770288
- Testing
- Anaerobic wingate test
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Obsessive-Compulsive Disorder
Personalized Computerized Inhibitory Control Training for OCD
This study will evaluate the effects of a computerized training program coupled with cognitive behavioral therapy (CBT) for OCD.
- Trial name
- NCT02378896
- Testing
- Personalized Computer Program, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- New York State Psychiatric Institute
Normal Physiology
Neurophysiology of Surround Inhibition in the Human Motor Cortex
Background: Movement disorders have many different causes and symptoms. Researchers still do not fully understand which parts of the brain are involved in fine movement.
- Trial name
- NCT03018262
- Testing
- TMS - sub-study 1, TMS - sub-study 2, TMS - sub-study 3
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obesity
Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss
Multiple pathways including peripheral and central hormones and neurotransmitters are involved in the regulation of food intake and body weight. One of the most studied pathways involves the melanocortin receptor.
- Trial name
- NCT00779519
- Testing
- TTP435
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- vTv Therapeutics
Balance Changes
Effect of the Suboccipital Inhibition Technique on Balance Changes
Postural balance is an essential capacity for functional autonomy and the performance of activities of daily living, relying on the continuous integration of visual, vestibular, and somatosensory information.
- Trial name
- NCT07670819
- Testing
- Intervention Technique
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Atherosclerosis
A Study to Evaluate the Safety, Tolerability, and Activity of Intravenous MLDL1278A in Patients on Standard-of-Care Therapy for Stable Atherosclerotic Cardiovascular Disease (GLACIER)
This is a Phase II (proof-of-activity), double-blind, placebo-controlled, randomized, multicenter study of MLDL1278A (also known as BI-204) involving patients on standard-of-care therapy for atherosclerotic cardiovascular disease…
- Trial name
- NCT01258907
- Testing
- MLDL1278A, statin, stable dose
- Where
- 24 sites in United States, Canada
- Volunteers
- 147 people
- Sponsor
- Genentech, Inc.
Rheumatoid Arthritis
A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate
This 3 arm study assessed the efficacy of rituximab (MabThera®/Rituxan®) in the prevention of progression of structural joint damage in participants with active rheumatoid arthritis who had an inadequate clinical response to…
- Trial name
- SCORE (NCT00578305)
- Testing
- Rituximab, Methylprednisolone, Methotrexate
- Where
- 60 sites in Argentina, Brazil and 17 more
- Volunteers
- 185 people
- Sponsor
- Hoffmann-La Roche
Attentional Control Switching, Task Switching Between Modalities
Yoga Practice, Stress and Cognitive Performance
It has been indicated in recent research that Mindfulness-based interventions may offer possibilities of promoting human stress processing and reducing anxiety or depression.
- Conditions
- Attentional Control Switching, Task Switching Between Modalities, Inhibition, Stress
- Trial name
- NCT05232422
- Testing
- Hatha yoga course
- Where
- Austria
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Cocaine Addiction
Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder
Repetitive bilateral (left cathodal/ right anodal) transcranial Direct Current Stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) reduces craving and seems to decrease relapse risk in addiction.
- Trial name
- NCT03025321
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- Netherlands
- Volunteers
- 59 people
- Sponsor
- Erasmus Medical Center
Idiopathic Parkinson's Disease
Dopamine Effect on Inhibitory Control
The effect of Levodopa medication on inhibitory control in Parkinson's patients is extremely debated despite the fact that this has potential clinical and therapeutic implications.
- Trial name
- DEI (NCT03665493)
- Testing
- PD patients H&Y=1.5-2 Medications ON, PD patients H&Y=1.5-2 Medications OFF, Healthy age-matched controls
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giovanni Mirabella
Psychomotor Speed, Sustained Attention
Effects of Exposure to a Single-electrode Electroencephalography-guided Binaural Beat Audio Track on Sustained Attention and Subjective Well-being Among Healthy Adults
This study aims to explore the potential of binaural beats, adjusted in real-time via EEG feedback, to positively influence brain states related to relaxation, focus, and cognitive performance.
- Conditions
- Psychomotor Speed, Sustained Attention, Inhibitory Control, Memory Encoding
- Trial name
- NCT07165899
- Testing
- EEG-Guided Binaural Beat Audio
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Attention Deficit Disorder With Hyperactivity
Efficacy of the Apollo System for Children With ADHD
To determine the extent to which the Apollo System is effective in reducing symptomatology associated with ADHD.
- Trial name
- NCT05308706
- Testing
- 8 weeks of home based use.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Michigan State University
Social Anxiety
Virtual Reality Exposure for Socially Anxious Adolescents
Overall in this project, the primary goal is to evaluate the efficacy of virtual reality exposure (VRE) for adolescents with elevated social anxiety using a three-arm randomized controlled trial: (1) virtual reality exposure…
- Trial name
- VIRTUS (NCT06379633)
- Testing
- In vivo exposure, (Virtual reality) exposure
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Hepatocellular Carcinoma
A Phase II/III Clinical Study on Inhibitory Effects of E0167 on Recurrence of Hepatocellular Carcinoma
The purpose of this study is to determine the superiority of inhibitory effects and safety of Menatetrenone (E0167) on recurrence in patients with hepatocellular carcinoma.
- Trial name
- NCT00165633
- Testing
- Menatetrenone
- Where
- 30 sites in Japan
- Volunteers
- 540 people
- Sponsor
- Eisai Limited
Ischemic Heart Disease
Effect of Amlodipine on Anti-platelet Drug Effect in Patients With Coronary Artery Disease
Clopidogrel can reduce risk of cardiovascular disease by inhibiting platelet aggregation. It is metabolized to an active drug by a liver enzyme.
- Trial name
- NCT01203696
- Testing
- Amlodipine
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Ruttonjee Hospital
Atopic Dermatitis Eczema
Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)
This was a Phase 3, 4-week, double-blind study to assess the safety and efficacy of ARQ-151 cream compared to vehicle cream applied once daily (qd) for 4 weeks in children 2 to 5 years of age with atopic dermatitis (AD).
- Trial name
- NCT04845620
- Testing
- Roflumilast Cream 0.05%, Vehicle Cream
- Where
- 76 sites in United States, Canada
- Volunteers
- 652 people
- Sponsor
- Arcutis Biotherapeutics, Inc.