Clinical trials: Initial Caries
White Spot Lesion of Tooth
Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions
this study aimed to assess the effect of the application of the low-viscosity Icon resin infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-, and 12-m follow-up periods.
- Trial name
- NCT05757440
- Testing
- Icon resin application
- Where
- Egypt
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Caries; Initial
Sealing of Initial Occlusal Caries Using Fissure Sealants
The purpose of this study is to compare the performance of newly introduced bioactive resin based pits and fissure sealant versus fluoride releasing resin based pits and fissure sealant in initial carious lesions of fissures in…
- Trial name
- NCT05891288
- Testing
- BioCoat® by Premier®, 3M™ Clinpro™ Sealant.
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Dental Caries
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars
This randomized controlled clinical trial aims to evaluate and compare the retention, caries prevention, microleakage, and fluoride release of three types of pit and fissure sealants-hydrophilic, nanofilled hydrophobic, and…
- Trial name
- NCT07052526
- Testing
- Prevention, Prevention of caries, Prevention therapy
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Caries, Dental
Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries
This study will be conducted to assess diagnostic predictive values of a light induced fluorescence intraoral camera versus those of the visual-tactile assessment method according to modified ICDAS-II criteria in clinical
- Trial name
- NCT03586713
- Testing
- light induced fluorescence camera
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children, Vital Pulp Therapy
Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity.
- Trial name
- NCT06372561
- Testing
- Mineral trioxide aggregate (dressing material), Melatonin (dressing material)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Caries; Initial, Caries Active
Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste
This study will be conducted to Clinically evaluate Bioactive Silica Based with calcium booster (Refix technology) toothpaste and Sodium Fluoride varnish versus conventional fluoride toothpastes in management of white spot…
- Trial name
- NCT07120243
- Testing
- Toothpaste Product, Varnishes, Fluoride
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Dental Caries
Novel Dental Cements (ALBO-MPCA) in Patients With Caries
Cements on the base of the calcium silicates, like Mineral trioxide aggregate (MTA), and our cement mixture ALBO MPCA, as the object of this clinical trial, have various clinical applications.
- Trial name
- NCT07507136
- Testing
- ALBO MPCA
- Where
- Bosnia and Herzegovina
- Volunteers
- 20 people
- Sponsor
- Albos d.o.o. Beograd
Permanent Molars, Dental Caries
Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children
The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to…
- Conditions
- Permanent Molars, Dental Caries, Tooth Decay, Permanent First Molar Caries
- Trial name
- HTCC-SM (NCT07186673)
- Testing
- Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method
- Where
- 2 sites in Syria
- Volunteers
- 10 people
- Sponsor
- Latakia University
Caries; Initial, Pit and Fissure Caries
Retention Rate of Self-etch Resin Based Sealant With and Without Prior Sandblasting
The aim of the study is to clinically assess the effect of sandblasting prior to self-etch resin based sealant on its retention after one year follow up.
- Trial name
- NCT04929327
- Testing
- Self etch Pit and fissure sealant application (prevent seal), Self etch Pit and fissure sealant application (prevent seal) with prior sandblasting, Total etch resin based sealant ultraseal xt
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth
Effect of Bioactive Resin Material Containing S-PRG Filler on White Spot Lesions
the effect of bioactive resin composite containing S-PRG filler will be tested as the material of choice for attachments bonded on teeth prior to the use of orthodontic clear aligners compared to the conventionally used flowable…
- Trial name
- NCT07715942
- Testing
- Bioactive resin composite containing S-PRG filler, Conventional flowable composite is used for the attachments for the clear orthodontic aligners
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
White Spot Lesion of Tooth
Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children
One hundred children with white spot lesions on their teeth were divivided into 5 groups of different remineralizing agents to assess their effect on color change and remineralization
- Trial name
- RCT (NCT06821724)
- Testing
- Casein phosphopeptide-amorphous calcium phosphate, Casein phosphopeptide-amorphous calcium phosphate + fluoride, Nano hydroxyapatite paste
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
White Spot Lesion of Tooth
Treatment of Postorthodontic White Spot Lesions
Dental caries is the destruction of the tooth structure in the presence of organic acids produced by cariogenic bacteria located in the dental biofilm (Dowker et al., 1999 and Robinson et al., 2000).Tooth enamel comprises 90%…
- Trial name
- NCT03217084
- Testing
- MI varnish GC, White varnish 3M
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion of Tooth
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary…
- Trial name
- NCT03526276
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
White Spot Lesion of Tooth, Gingival Inflammation
EFFECTIVENESS of WATER FLOSS in PLAQUE REMOVAL and PREVENTION of WHITE SPOT LESIONS in ORTHODONTIC PATIENTS: a RANDOMISED CONTROLLED CLINICAL TRIAL
This clinical trial aims to learn if water floss is as efficient as other interdental cleaning tools and can prevent plaque accumulation and white spot lesions (WSLs) in orthodontic patients.
- Conditions
- White Spot Lesion of Tooth, Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- WATER FLOSS (NCT06752291)
- Testing
- water flosser
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Malaya
White Spot Lesion of Tooth
White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial
The aim of this study is to evaluate the effectiveness of calcium fluoride nanoparticles containing orthodontic primer in preventing or decreasing the incidence WSLs over a period of 6 months in patients with fixed orthodontic…
- Trial name
- NCT04994314
- Testing
- nCaF2 primer, Control primer
- Where
- Iraq
- Volunteers
- 31 people
- Sponsor
- University of Baghdad
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions
The current study aimed to evaluate the color change potential of wheat grass and white tea on post orthodontic white spot lesions (WSLs).
- Trial name
- NCT06976385
- Testing
- White tea, Wheat grass solution
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Enamel Lesions, Dental Caries
Comparison of Different Methods of Enamel Preparation Before Pit and Fissure Sealants
This study concerns the prevention of dental caries by sealing pits and fissures of permanent molars with a photopolymerizable resin.
- Trial name
- NCT02594020
- Testing
- air abrasion, sono abrasion, dental bur
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Dental Caries, Parents
Assessment of the Age, Reasons, Oral Health Status and Dental Treatment Needs of Children in Their First Dental Visit
to asses the age, reasons, oral health status and dental treatment needs of children in their first dental visit.
- Conditions
- Dental Caries, Parents, Parenting, Pain
- Trial name
- NCT04183777
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental
Atraumatic Restorative Treatment Sealants in First Permanent Molars
The aim of this bi-center study was to evaluate the retention and caries-preventive effect of Atraumatioc Restorative Treatment (ART) sealants, using two glass ionomer cement (GIC) versus non-sealant on first permanent molars of…
- Trial name
- NCT03667768
- Testing
- Glass ionomer sealant, Non-sealant (toothbrushing)
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo