Clinical trials: Initial Dental Caries
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Remineralization of White Spot Lesions Using Self-Assembling Peptide P11-4 in Primary Anterior Teeth A Randomized Clinical Trial
This study is a randomized controlled clinical trial on primary anterior teeth of 3-5 year-old patients suffering from white spot lesions (ICDAS system II scores 1-2).
- Trial name
- NCT03927794
- Testing
- Self-Assembling Peptide P11-4
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries in Children
Clinical and Radiographic Evaluation of Resin Endocrown as Long Term Interim Restoration Versus Stainless Steel Crown for Endodontically Treated First Permanent Molar in Children: Randomized Controlled Pilot Study.
management of endodontically treated first permanent molar with deep dental caries is one of the challenging procedure that the operator face.
- Trial name
- NCT05250609
- Testing
- Endocrown "composite".
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions
The current study aimed to evaluate the color change potential of wheat grass and white tea on post orthodontic white spot lesions (WSLs).
- Trial name
- NCT06976385
- Testing
- White tea, Wheat grass solution
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Dental Caries Extending Into Dentin
Clinical Evaluation of Extensive Direct Composite Restorations With Polyethylene Fiber
The aim of this clinical trial was to compare the clinical performances of composite resin restorations with/without the polyethylene fiber to the first permanent molar teeth with extensively carious pediatric patients.
- Trial name
- NCT04612543
- Testing
- Genial Posterior Composite with Polyethylene Fiber, Genial Posterior Composite
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kafkas University
White Spot Lesion of Tooth
Effect of Different Pastes on Remineralization of Early Caries Lesions in Primary Teeth
This study is a randomized controlled trial involving 118 children ages between 4 and 5 years to assess the remineralization effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) on white spot lesions in primary…
- Trial name
- NCT03526276
- Testing
- CPP-ACP paste, Fluoride toothpaste, Both (Fluoride and CPP-ACP)
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
White Spot Lesion of Tooth
Color Masking Potential of Bioactive and ICON Materials
The non cavitated white-spot lesion (WSL) occurs after sometime during fixed orthodontic treatments, and their treatment is mandatory before going into frank cavitation.
- Trial name
- NCT06402500
- Testing
- Icon Infiltrant, Bioactive infiltrant
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries in Children
Can Zirconia Crown be the First Choice for Primary Teeth?
Objective: Early loss of primary teeth due to caries, can cause occlusion disorders, aesthetic problems, nutritional problems, abnormal language habits, speech disorders and psychological problems temporary or permanent.
- Trial name
- NCT04574180
- Testing
- Dental Crown
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
White Spot Lesion of Tooth
Effect of Bioactive Resin Material Containing S-PRG Filler on White Spot Lesions
the effect of bioactive resin composite containing S-PRG filler will be tested as the material of choice for attachments bonded on teeth prior to the use of orthodontic clear aligners compared to the conventionally used flowable…
- Trial name
- NCT07715942
- Testing
- Bioactive resin composite containing S-PRG filler, Conventional flowable composite is used for the attachments for the clear orthodontic aligners
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Initial Caries, Arrested Dental Caries
Early Caries Lesion Management Observational Study
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved…
- Conditions
- Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries
- Trial name
- ELMO (NCT04933331)
- Testing
- Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant
- Where
- 4 sites in United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- CareQuest Institute for Oral Health
Dental Caries
Novel Dental Cements (ALBO-MPCA) in Patients With Caries
Cements on the base of the calcium silicates, like Mineral trioxide aggregate (MTA), and our cement mixture ALBO MPCA, as the object of this clinical trial, have various clinical applications.
- Trial name
- NCT07507136
- Testing
- ALBO MPCA
- Where
- Bosnia and Herzegovina
- Volunteers
- 20 people
- Sponsor
- Albos d.o.o. Beograd
Demineralization, Tooth, White Spot Lesion of Tooth
Preventive Effects of Silver Diamine Fluoride on Early Enamel Caries
Fixed orthodontic patients are at risk of developing dental caries. Topical application of fluoride varnish (FV) around the orthodontic brackets and using fluoridated mouth rinses have been suggested to prevent the formation of…
- Conditions
- Demineralization, Tooth, White Spot Lesion of Tooth, Fixed Appliances, Early Caries Lesions
- Trial name
- NCT06797882
- Testing
- Silver diamine fluoride- potassium iodide, Fluoride varnish, 0.9 % saline
- Where
- Malaysia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Caries, Caries,Dental
Extraction of the Compromised First Permanent Molars
Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which…
- Trial name
- FPM (NCT06231823)
- Testing
- Extraction
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Carious Lesion, Caries; Initial
Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious
This study aimed to asses the effect of different remineralizing agents on the initial carious lesions at diff rant after immediately after treatment (as baseline), six months and one year.
- Trial name
- NCT07574814
- Testing
- ER-CR Laser, Without ER-CR Laser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Delta University for Science and Technology
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Investigation of the Performance of Epinamel for Dental White Spot Lesions
Mintech-Bio Ltd is a UK-based start-up company which was created to turn 14 years of research from our co-founder Dr Alvaro Mata at Queen Mary University into a real-world product.
- Trial name
- NCT07730359
- Testing
- Varnish
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Mintech Bio Ltd
White Spot Lesion of Tooth
Clinical Outcomes, Cost-Effectiveness and Patient Satisfaction of Two Resin Infiltration Systems for The Management of White Spot Lesions
The aim of this study is to clinically evaluate and compare the color matching of white spot lesions (WSLs) following treatment with two resin infiltration systems: ICON resin infiltration and I-Mate resin infiltration.
- Trial name
- NCT07799350
- Testing
- light cured low viscosity resin infiltration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentist's Role
Two Preventive Measures on Caries Progression in Mixed Dentition Patients.
Primary Objective: Assessing the clinical effect of SDF and Laser on the prevention of initial caries progression with and without pits and fissure sealants in both permanent and primary molars.
- Trial name
- NCT06119126
- Testing
- SDF1, Diode Laser, Pit Fissure Sealant
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
White Spot Lesion of Tooth
Treatment of Postorthodontic White Spot Lesions
Dental caries is the destruction of the tooth structure in the presence of organic acids produced by cariogenic bacteria located in the dental biofilm (Dowker et al., 1999 and Robinson et al., 2000).Tooth enamel comprises 90%…
- Trial name
- NCT03217084
- Testing
- MI varnish GC, White varnish 3M
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Cost-efficacy of Silver Diammine Fluoride in Erupting Molars
This study aims to evaluate the cost-effectiveness of 30% silver diammine fluoride in the treatment of clinically caries lesions in enamel, on occlusal surfaces in first permanent molars compared to a control group that performs…
- Trial name
- NCT01508611
- Testing
- 30% silver diammine fluoride, Oral hygiene
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Effectiveness of Different Toothpastes in Treating White Spot Lesions
This randomized clinical trial and laboratory study was conducted to: Compare the effectiveness of zinc-carbonated nano-hydroxyapatite, arginine, and fluoride-containing toothpastes for treating white spot lesions associated with…
- Trial name
- NCT06128434
- Testing
- zinc carbonate nano-hydroxyapatite toothpaste, 8% arginine toothpaste, Fluoride toothpaste
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University