Clinical trials: Injectables
Tooth Mobility, Injectable Platelet-rich Fibrin
Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement
One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which…
- Trial name
- NCT06302296
- Testing
- injectable form of PRF
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Hama University
Osteoarthritis
A Study of Hyaluronate Injectable Viscosupplement for Treatment of Osteoarthritis of the Knee
The study is a prospective, multi-center, randomized, three-arm, parallel group, clinical study to evaluate the superiority of 3 weekly intra-articular (IA) doses of 2 mL of Investigational hyaluronate as compared to placebo…
- Trial name
- NCT02495857
- Testing
- Hyaluronate Injectable Viscosupplement, Euflexxa IA injection
- Where
- 2 sites in United States
- Volunteers
- 599 people
- Sponsor
- Actavis Inc.
CRPC, Prostate Cancer
A Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension), Administered to Patients With Metastatic Castration-Resistant Prostate Cancer
The purpose of this study is to evaluate the efficacy and safety BIND-014 in patients with metastatic castration-resistant prostate cancer (mCRPC).
- Trial name
- NCT01812746
- Testing
- BIND-014
- Where
- 8 sites in United States
- Volunteers
- 42 people
- Sponsor
- BIND Therapeutics
Patients With Moderate to Severe Perioral Lines
JUVEDERM® Ultra XC vs. Belotero Balance® for Perioral Lines
A prospective, randomized, controlled, multi-center study of the safety and effectiveness of JUVEDERM® Ultra XC injectable gel versus Belotero Balance® for perioral lines
- Trial name
- NCT01970397
- Testing
- JUVEDERM® Ultra XC, Belotero Balance®
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Allergan
Face; Atrophy
DA-13-007 Versus Sculptra for the Treatment of Nasolabial Folds Wrinkles
Study DA-13-007 is a randomized, evaluator-blinded, within subject (split face) multicenter clinical study of DA-13-007l (Injectable poly-l-lactic acid) compared to SCULPTRA in the treatment of nasolabial fold wrinkles.
- Trial name
- NCT02310490
- Testing
- DA-13-007 right with left side Sculptra left side, DA-13-007 left with left side Sculptra right side
- Where
- 4 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- DermAvance
Schizophrenia, Schizoaffective Disorder
A Comparison of Long-acting Injectable Medications for Schizophrenia
The purpose of this research study is to compare the "real-world" effectiveness of two FDA-approved and widely used long-acting injectable antipsychotic medications (paliperidone palmitate and haloperidol decanoate) in patients…
- Trial name
- ACLAIMS (NCT01136772)
- Testing
- haloperidol decanoate, paliperidone palmitate
- Where
- 22 sites in United States
- Volunteers
- 311 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia
A Study of Long-acting Injectable Risperidone in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder
The purpose of this study is to document the long-term safety and tolerability of risperidone, formulated as a long-acting injectable, in the treatment of patients with schizophrenia or schizoaffective disorder; in addition, to…
- Trial name
- NCT00210691
- Testing
- Risperidone
- Volunteers
- 273 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Infraorbital Hollowing
Study to Assess Effectiveness and Adverse Events of JUVEDERM VOLBELLA With Lidocaine Injection in Correcting Infraorbital Hollowing in Chinese Adult Participants
Aged appearance is often caused by an infraorbital hollowing, which is characterized as a sunken appearance of the eye that results in the casting of a dark shadow over the nasal lower eyelid, giving a fatigued appearance.
- Trial name
- NCT05088980
- Testing
- VOLBELLA with Lidocaine
- Where
- 7 sites in China
- Volunteers
- 160 people
- Sponsor
- Allergan
Opioid Overdose
Clinical Outcomes From Nalmefene
The purpose of this study is to assess the effectiveness of nalmefene relative to naloxone for the reversal of opioid intoxication in emergency department (ED) settings.
- Trial name
- COINED (NCT05808881)
- Testing
- Nalmefene Hydrochloride Injection, Naloxone Hydrochloride Injection
- Sponsor
- Purdue Pharma LP
Periodontitis (Stage 3)
Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aims to evaluate the effectiveness of non-surgical periodontal therapy (NSPT) with and without the adjunctive use of injectable platelet-rich fibrin (I-PRF) in patients with chronic…
- Trial name
- NCT07090265
- Testing
- non-surgical periodontal therapy, non-surgical periodontal therapy + I-PRF
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Overweight
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable…
- Trial name
- NCT06584916
- Testing
- Orforglipron
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 376 people
- Sponsor
- Eli Lilly and Company
Dental, Implant Osseointegration
Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft
Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Conditions
- Dental, Implant Osseointegration, Ozone Therapy, Bone Graft
- Trial name
- NCT07368114
- Testing
- Immediate implant placement, β-tricalcium phosphate Injectable Bone Graft, Ozonated olive oil gel
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Skin Aging
Randomized Trial of Combination Treatment With Sofwave and Sculptra
Evaluation of treatment on the upper arm with Sculptra and Sofwave on the same day versus Sofwave followed by Sculptra 1 month later.
- Trial name
- NCT07342452
- Testing
- Sofwave, Sculptra
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Temporomandibular Joint Pain, Arthrocentesis
Comparison of Hyaluronic Acid, Injectable Platelet-Rich Fibrin, and Prolotherapy in TMJ Arthrocentesis
This study aimed to compare the clinical effectiveness of different intra-articular adjunctive therapies used with temporomandibular joint (TMJ) arthrocentesis in patients with temporomandibular joint disorders.
- Trial name
- NCT07479693
- Testing
- Temporomandibular Joint Arthrocentesis, Hyaluronic Acid (Orthovisc), Injectable Platelet-Rich Fibrin (i-PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Ondokuz Mayıs University
Micropenis
Shafer Width and Girth: The Use of Injectable Fillers for Penile Enhancement
Injectable filler will be performed by Principal Investigator under sterile conditions for the enhancement of girth and surface area of the penis.
- Trial name
- NCT04755634
- Testing
- Hyaluronic Acid
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shafer Clinic Fifth Avenue
Lichen Planus
Use of Injectable Platelet Rich Fibrin in Lichen Planus
Platelet Rich Fibrine (PRF), which promotes wound healing by supporting angiogenesis, immunity and epithelial proliferation phases.
- Trial name
- NCT03265093
- Testing
- Platelet Rich Fibrin Injection, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Monitored Anesthesia Care
A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion
The purpose of this study is to explore the pharmacokinetics (PK) and pharmacodynamics (PD) of LUSEDRA® administered as a continuous infusion or bolus compared with continuous infusion of propofol injectable emulsion.
- Trial name
- NCT01308541
- Testing
- arm 1, LUSEDRA, Propofol (arm 3)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Renal Colic
Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial
Kidney stone is one of the most common diseases in every human society and also Iran. What is normally used to treat renal colic pain is Intravenous Opioid with a variety of side effects including hypotension, respiratory…
- Trial name
- NCT01906762
- Testing
- Acetaminophen, Morphine
- Volunteers
- 124 people
- Sponsor
- Seyed Mehdi Pourafzali
Plantar Fasciitis
Comparative Study of Amniotic Membrane Injectable in the Treatment of Recalcitrant Plantar Fasciitis
The purpose of this study is to determine whether the AmnioFix Injectable human amniotic membrane is effective in the treatment of recalcitrant plantar fasciitis.
- Trial name
- NCT01659827
- Testing
- Marcaine, 0.5cc AmnioFix, 1.25cc AmnioFix
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- MiMedx Group, Inc.
Cocaine Dependence, Alcohol Dependence
VIVITROL as a Treatment for Cocaine and Alcohol Dependence
To evaluate the efficacy of VIVITROL (naltrexone for extended-release injectable suspension) for the treatment of co-occurring cocaine and alcohol dependence
- Trial name
- NCT00777062
- Testing
- VIVITROL (Naltrexone extended-release injectable suspension)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania