Clinical trials: Injection Pain
Injection Site Irritation
Ondansetron as a Strategy for Reducing Propofol Injection Pain in Pediatrics: a Randomized Controlled Trial
This study is a randomized, single-site clinical trial that will take place at Children's Healthcare of Atlanta at Egleston. The investigators want to see if in pediatric patients, giving Zofran prior to propofol, reduces the…
- Trial name
- NCT05378113
- Testing
- Ondansetron, Lidocaine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Cervical Radiculopathy, Cervical Spondylosis
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
Study Purpose: This study is intended to monitor outcomes for 1 year following cervical TFESI. Based on current clinic volume and enrollment rates into a current study of cervical epidural injections that is nearing completion…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
- Trial name
- NCT04544683
- Testing
- Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah
Pertrochanteric Fracture
Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery
This is a phase I, randomized, single-blind, placebo-controlled, single-center study of the effects of surgical site injection on pain and narcotic utilization in participants who undergo surgery for lower extremity fractures.
- Trial name
- NCT03693404
- Testing
- Marcaine, Duramorph , ketorolac, Bupivacaine (Marcaine), General Anesthetics
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- NYU Langone Health
Pain
Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy
Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours.
- Trial name
- NCT01242644
- Testing
- pain pump containing ropivacaine, saline pain pump with injectable medication, ropivacaine, ketorolac , morphine sulfate
- Volunteers
- 48 people
- Sponsor
- University of South Alabama
Plantar Fasciitis
DaxibotulinumtoxinA for Injection for the Treatment of Plantar Fasciitis
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center trial of a single administration of DaxibotulinumtoxinA (DAXI) (high-dose; low-dose) for injection versus placebo for the management of Plantar…
- Trial name
- NCT03825315
- Testing
- DAXI 80 U, DAXI 120 U
- Where
- 20 sites in United States
- Volunteers
- 155 people
- Sponsor
- Revance Therapeutics, Inc.
Osteoarthritis, Knee
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
This is a randomized, double-blind, placebo-controlled, 2-injection, 52-week study to evaluate the efficacy and safety of intra-articular injections of CNTX-4975-05 in subjects with chronic, moderate-to-severe osteoarthritis knee…
- Trial name
- NCT03660943
- Testing
- CNTX-4975-05
- Where
- 30 sites in United States
- Volunteers
- 332 people
- Sponsor
- Centrexion Therapeutics
Postoperative Pain, Intra-articular Injection
Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain
Arthroscopic meniscus surgeries are the most frequent orthopedic procedures. The objective of the study is to compare the effects of intraarticular local anesthetic and adjuvant (dexmedetomidine vs magnesium) combinations in…
- Conditions
- Postoperative Pain, Intra-articular Injection, Dexmedetomidine, Magnesium Sulfate
- Trial name
- NCT03479216
- Testing
- Precedex, Magnesium Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Derince Training and Research Hospital
Osteoarthritis of the Knee
ADSC Injections for Pain Management of Osteoarthritis in the Human Knee Joint
This safety and feasibility study used autologous adipose-derived stromal cells (ADSC), the stromal vascular fraction (SVF), to treat 8 osteoarthritic (OA) knees in 6 patients of grade I to III (K-L scale) with initial pain of 4…
- Trial name
- NCT02357485
- Testing
- ADSC
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Fodor, Peter B, M.D.
Osteoarthritis, Rheumatoid Arthritis
Reciprocating Medical Devices - a Study of a New Safety Device
The study design is a randomized study to directly compare the performance and the outcome of syringe and needle procedures with a standard syringe or the new reciprocating procedure device (RDP), which is a type of safety…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Trauma, Thyroid Nodule
- Trial name
- RPD (NCT00651625)
- Testing
- Reciprocating Procedure Device (RPD) - AVANCA Re No. 1091001, conventional syringe - BD Ref 309604
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- University of New Mexico
Lip Augmentation
A Multicenter, Double-blind, Randomized, Controlled, Roll-over Retreatment Study of the Safety and Pain Associated With Injections of PN40082, RV001 With Topical Anesthetic or RV001 for Lip Augmentation
The purpose of this study is to evaluate the safety of repeat injections and pain associated with injection of PN40082 and comparative pain associated with RV001 with a topical anesthetic and RV001 for lip augmentation.
- Trial name
- NCT04029545
- Testing
- PN40082
- Where
- 5 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.
Pain
Intravenous Dexamethasone to Increase the Analgesic Duration of Interscalene Block
Interscalene brachial plexus block provides excellent but time limited analgesia. Intravenous dexamethasone increases the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder arthroscopic surgery.
- Trial name
- NCT02412657
- Testing
- Dexamethasone, Normal Saline
- Where
- 3 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Acute Pain
Volume Versus Concentration: Clinical Effectiveness of Single Shot Quadrates Lumborum Block Using Either a High Volume/Low Concentration or Low Volume/High Concentration Injectate for Total Hip Arthroplasty.
There is Controversy about what is more critical volume or concentration to achieve an optimum analgesic treatment with quadratus lumborum block.
- Trial name
- NCT04259645
- Testing
- Drug: Bupivacaine 0.375% 20 mL, Drug: Bupivacaine 0.375% diluted to 0.1875%
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Anna Uskova
Osteoarthritis of the Knee
Study of FX006 in Patients With Osteoarthritis of the Knee
The purpose of this study was to evaluate the safety, efficacy and pharmacokinetics of FX006 in patients with osteoarthritis of the knee.
- Trial name
- NCT01487161
- Testing
- FX006, TCA IR
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 229 people
- Sponsor
- Pacira Pharmaceuticals, Inc