Clinical trials: Injection Pain
Total Knee Arthroplasty, Pain, Postoperative
Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty
Patients undergoing Primary Total Knee Arthroplasty will be randomized to receive either multimodal single injection adductor canal block with sham infusion catheter or continuous infusion of local anesthetic (control) for…
- Conditions
- Total Knee Arthroplasty, Pain, Postoperative, Adductor Canal Block
- Trial name
- NCT02991404
- Testing
- Multimodal Peripheral Nerve Block Injection, Single Shot Adductor Canal Block, Initial Bolus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Injection, Pain Management
Effects of Cold Spray and Buzzy Device an Pain and Fear During Penicillin Injection
This study investigates the effect of cold spray and Buzzy devices on pain and fear experienced during penicillin injections. There are three groups: a cold spray and Buzzy device, and a control group.
- Conditions
- Injection, Pain Management, Fear
- Trial name
- NCT07418021
- Testing
- Cold Spray Intervention Group, Buzy Device Intervention Group, Control Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Pain
Effect of Shotblocker and Palm Stimulator
This study discusses the advancements in nursing, particularly focusing on intramuscular injections, their complications, and innovative non-pharmacological methods such as the Shotblocker and palm stimulator to reduce pain.
- Trial name
- NCT06381804
- Testing
- shotblocker, palm stimulator
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Osteoarthritis, Knee
Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis
To evaluate the efficacy of Lyophilized amniotic fluid as compared to the Saline Injection, placebo control in the treatment of moderate osteoarthritis of the knee.
- Trial name
- NCT03074526
- Testing
- Amniotic Fluid
- Where
- 4 sites in United States
- Volunteers
- 156 people
- Sponsor
- MiMedx Group, Inc.
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Adult Patients for Pain Control During Spinal Injections (SI)
A three-group parallel randomized controlled trial to evaluate the efficacy of virtual reality analgesia (VRA) to decrease patient procedural pain and anxiety in the Adult patients undergoing Spinal Injections (SI).
- Trial name
- VR adult (NCT03787147)
- Testing
- Google Cardboard, Oculus, Lidocaine Hydrochloride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial was conducted to investigate the efficacy and safety of RF16001 local infiltration for analgesia after total hip arthroplasty.
- Trial name
- NCT07872826
- Testing
- RF16001 for injection, Ropivacaine hydrochloride injection, 0.9% sodium chloride injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pain
EXPAREL for Minimally Invasive Supracervical Hysterectomies
The aim of the of the study is a reduction in minimally invasive supracervical hysterectomy postsurgical pain, which may result in less need for supplemental opioid pain medications, fewer opioid related adverse events, and a…
- Trial name
- NCT03769714
- Testing
- Saline Solution for Injection, Exparel
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pain
Comparison Between the Dentapen and Vibraject
A split-mouth, controlled trial aimed to assess patient-reported pain levels during local anaesthesia administration to the buccal side of the maxillary posterior teeth using Vibraject-assisted injection and the Dentapen® system…
- Trial name
- NCT06790433
- Testing
- Vibraject, Dentapen
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Nurse's Role
The Effect of Telenursing on the Pain and Fear of Insulin Injection
Aim: The aim of the study is to examine the effects of nursing follow-up with telenursing on the pain and fear factors related to self-injection testing in diabetic individuals who are started on insulin therapy for the first…
- Trial name
- NCT06013826
- Testing
- Telenursing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Saglik Bilimleri University
Sacroiliac Joint Dysfunction
Effectiveness of 5% Dextrose Water Versus Corticosteroid Injection for Pain Management of SJD
The sacroiliac joint (SIJ) is identified as a potential origin of low back pain and referred pain to the lower limb, with a prevalence rate ranging from 7% to 30%.
- Trial name
- NCT06568887
- Testing
- Dextrose Water, Corticosteroid Injection
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Superior University
Pain, Postoperative
Investigating Temporalis and Masseter Botox Injection Before Orthognathic Surgery to Improve Postoperative Pain
Jaw surgery has become a very successful way to improve the appearance and functional needs of patients. Like any surgery, jaw surgery comes with a host of possible issues that patients may experience during their recovery.
- Trial name
- NCT04794504
- Testing
- Botox 100 UNT Injection, 0.9% Saline Injection
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kingsway Oral & Maxillofacial Surgery
Renal Colic, Urolithiasis
Sterile Water Injection vs Morphine for Renal Colic
This study aims to compare intradermal sterile water injections (ISWI) with intravenous morphine for pain relief in adults with acute renal colic caused by urinary stones.
- Trial name
- ISWI-Morph (NCT07378904)
- Testing
- Single Intradermal Sterile Water Injection, Multiple Intradermal Sterile Water Injections, Intravenous Morphine
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- University Tunis El Manar
Superior Hypogastric Plexus Block, Intraperitoneal Bupivacaine
Comparison of Superior Hypogastric Plexus Block and Peritoneal Bupivacaine in Pain Management
Background: Laparoscopic hysterectomy is one of the most frequently performed major surgeries in nonmalignant gynecological diseases.
- Trial name
- NCT06954896
- Testing
- Bupivacain, Dexketoprofen (KETAVEL 50 mg/2 ml), Intraperitoneal Bupivacaine spray
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Enes Celik
Retinal Disease, Diabetic Retinopathy
Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia
Vitreoretinal surgery has evolved to less invasive procedures, and it is used to treat a wide range of diseases. So anesthesia for vitreoretinal procedures has evolved, promoting adequate analgesia while reducing risks to the…
- Conditions
- Retinal Disease, Diabetic Retinopathy, Maculopathy
- Trial name
- NCT03902925
- Testing
- Topical lidocaine 2% jelly plus sub-tenon ropivacaine 10% injection, Peribulbar injection
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Diabetes, Diabetes Mellitus, Type 1
Evaluating the Use of Two Different Needles in Subjects With Diabetes
This trial is conducted in Europe. The aim of this trial is to compare two needle types when used with a disposable insulin injection pen in the everyday life setting of an insulin treated patient with diabetes.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Delivery Systems
- Trial name
- NCT00569426
- Testing
- NovoFine® needle 6 mm, NovoFine® needle 8 mm
- Where
- 10 sites in United Kingdom
- Volunteers
- 119 people
- Sponsor
- Novo Nordisk A/S
Injection Site Haematoma, Local Anesthetic Toxicity
U/S Guided SAPB Versus Conventional IV Analgesics in Postoperative Pain Management in MRM
The aim of this study is to compare the effect of ultra-sound guided serratus anterior plane block versus conventional IV analgesics in postoperative pain management in modified radical mastectomy (MRM)
- Trial name
- SAPB (NCT05126394)
- Testing
- ultrasound guided serratus anterior plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative
Comparison of Outcomes Between Intraosseous Femoral and Tibial Injection in Simultaneous Bilateral Total Knee Arthroplasty Patients
In patients with osteoarthritis of the knee whose pain cannot be relieved by conservative treatment, total knee arthroplasty (TKA) is the operation that increases the quality of life for the patient.
- Trial name
- NCT06243575
- Testing
- Multimodal Intraosseous Femoral Injection, Multimodal Intraosseous Tibial Injection
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Needlestick Injuries
The Influence of Injection Speed on Pain During Administration of Local Anaesthetic.
This study will investigate the influence of injection speed on pain during injection of lidocaine. It is anticipated that a longer injection time will lead to less pain for the patient during the injection.
- Trial name
- NCT02107742
- Testing
- Normal speed lidocaine injection, Slow lidocaine injection, Fast lidocaine injection
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology