Clinical trials: Injection Site
Triple Negative Breast Cancer, HER2-negative Breast Cancer
DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer
The purpose of the study is to find out if an investigational vaccine called Dendritic Cell (DC) vaccine given together with standard of care chemotherapy drugs can help people with Triple Negative and HR low positive breast…
- Trial name
- DecipHER (NCT05504707)
- Testing
- HER2 - primed Dendritic cells, HER3 - primed Dendritic cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Breast Neoplasms, Breast Neoplasm Female
Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery
Background: Mastectomies are traditionally performed under general anesthesia (GA), often with the addition of regional anesthesia for post-operative pain relief.
- Conditions
- Breast Neoplasms, Breast Neoplasm Female, Cancer, Breast, Breast Cancer
- Trial name
- TPVB (NCT05711030)
- Testing
- Thoracic paravertebral block multiple (3) injections, Thoracic paravertebral block single injection
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Extensive-stage Small-cell Lung Cancer
A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung Cancer
This Phase II study is a clinical study exploring the efficacy and safety of BL-M14D1 in combination with Atezolizumab in patients with extensive-stage small cell lung cancer.
- Trial name
- NCT07654400
- Testing
- BL-M14D1, Atezolizumab
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
Neoplasms, Hematologic Neoplasms
RD13-02 CAR-T Cell Injection for Patients With r/r CD7+ T-ALL/T-LBL
This is a single-arm, open-label, single-center, phase I study. The primary objective is to evaluate the safety of CD7 CAR-T therapy for patients with CD7-positive relapsed or refractory T-ALL/LBL, and to evaluate the…
- Conditions
- Neoplasms, Hematologic Neoplasms, Hematologic Diseases
- Trial name
- NCT05902845
- Testing
- RD13-02 cell infusion
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Xiaoyu Zhu
Neoplastic Disease, Glioblastoma
Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma
This global clinical trial which evaluates the efficacy and safety of TLX101-Tx, an investigational radiopharmaceutical therapy, in combination with lomustine versus lomustine alone in adult patients with first recurrence of…
- Conditions
- Neoplastic Disease, Glioblastoma, Glioblastoma (GBM), Glioblastoma Multiform
- Trial name
- IPAX BrIGHT (NCT07100730)
- Testing
- TLX-101-Tx + Lomustine, TLX101-Tx
- Where
- 9 sites in Australia, Austria and 2 more
- Volunteers
- 50 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Limited
Lung Cancer (NSCLC)
An Open-label, Single-arm Clinical Study of Stapokibart Injection in Combination with Tislelizumab Injection in Patients with Non-Small Cell Lung Cancer
This is a single-arm study evaluating the efficacy and safety of Stapokibart Injection in combination with Tislelizumab Injection in patients with driver gene-negative NSCLC who have failed prior PD-1/PD-L1 inhibitor therapy.
- Trial name
- NCT06883552
- Testing
- Tislelizumab Injection
- Volunteers
- 21 people
- Sponsor
- Sichuan University
Breast Neoplasm, Carcinoma, Ductal, Breast
Sentinel Lymph Node Identification in the Axilla of Women With Breast Cancer Using Ultrasound and Iron Injection
This study evaluates a new method of testing the lymph nodes in the armpit of patients with breast cancer for tumor involvement.
- Conditions
- Breast Neoplasm, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating
- Trial name
- NCT02610920
- Testing
- Iron-tracer guided axillary ultrasound and biopsy, Iron tracer
- Sponsor
- Columbia University
Muscle Spasticity, Stroke
Botulinum Toxin A Adult Gastrocnemius Muscle Study
The study aims to compare the effectiveness of BOTOX-A® (botulinun toxin A) placed between two different injection sites, namely at the proximal portion of the gastrocnemius(GCM) versus at the midbelly of the GCM.
- Trial name
- BTX-A (NCT01278576)
- Testing
- BOTOX-A®
- Where
- 2 sites in South Korea
- Volunteers
- 40 people
- Sponsor
- The Catholic University of Korea
Stomach Neoplasms
Botulinum Toxin for Stomach Cancer Treatment
Preclinical studies at our institution, using a genetic mouse model of gastric cancer, strongly suggest that innervation of the stomach wall is required not only for the development, but also for the progression of gastric…
- Trial name
- NCT01822210
- Testing
- Botox
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- St. Olavs Hospital
HIV I Infection, Injection Pain
Impact of Pain From Injectables Antiretroviral Treatments in HIV-1 Patients Based on the Injection Site (Ventrogluteal or Dorsogluteal) and the Use or Non-use of Virtual Reality Headset
This is a multicenter, randomized, open-label study with a cross-over design. The objective of this project is to compare the intensity of pain induced by injectable antiretroviral (ARV) treatment (Cabotegravir® and Rilpivirine®)…
- Trial name
- VIHINJECT (NCT06834113)
- Testing
- Dorsogluteal intramuscular injection
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Type 2 Diabetes Treated With Insulin
A Study to Evaluate Time in Range in Type 2 Diabetics Using Afrezza® Plus Basal Insulin Compared to Multiple Daily Injections
The purpose of this study is to collect CGM, A1c and Quality of Life data in subjects with Type 2 diabetes before and after transitioning from Multiple Daily Injections to Basal plus Bolus with Afrezza® inhaled insulin.
- Trial name
- NCT04125082
- Testing
- Afrezza Inhalant Product
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Diabetes and Glandular Disease Clinic
Myasthenia Gravis
Evaluate the Safety of HBM9161 (HL161) Subcutaneous Injection in Patients With Generalized Myasthenia Gravis
The primary study objective is to evaluate medium- and long-term safety of HBM9161 in combination with background treatment for gMG patients through the observation on adverse events and laboratory abnormalities during study…
- Trial name
- NCT05332210
- Testing
- HBM9161 Injection (680mg)
- Where
- China
- Volunteers
- 111 people
- Sponsor
- Harbour BioMed (Guangzhou) Co. Ltd.
Breast Neoplasm, Shoulder Capsulitis
Improvement of Range of Motion in Frozen Shoulder in Breast Cancer Survivors
The prevalence of shoulder joint disease is high in breast cancer patients. The cause of adhesive capsulitis is not clearly identified.
- Conditions
- Breast Neoplasm, Shoulder Capsulitis, Range of Motion
- Trial name
- NCT04640220
- Testing
- Intra-articular steroid injection
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Yeungnam University Hospital
Colorectal Cancer
Evaluating the Safety and Efficacy of SB Injection in Patients With Advanced or Metastatic Colorectal Cancer
The purpose of this study is to determine efficacy of SB injection in Colorectal Cancer.
- Trial name
- NCT01305980
- Testing
- SB injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- SBPharmaceutical IND, Co., LTD
Metastatic Breast Cancer
Doxorubicin HCL Liposome Injection (DOXIL) in Combination With Abraxane in Patients With Metastatic Breast Cancer
Dose Finding and Efficacy Evaluation of DOXIL (Doxorubicin HCL Liposome Injection) in Combination with Abraxane (Abraxane) in Patients with Metastatic Breast Cancer (MBC) [Phase I and II]
- Trial name
- NCT00442260
- Testing
- DOXIL, Abraxane
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- West Virginia University
Osteoarthitis, Osteoarthritic Knee Pain
Patient Pain and Function in Medial Knee Osteoarthritis After Anteromedial vs Anterolateral Intra-Articular Corticosteroid Injection
The primary purpose of this study is to find out if there is a difference in pain experienced in patients with knee arthritis of the inside of their knee if they get a steroid injection on the inside or outside of their knee.
- Conditions
- Osteoarthitis, Osteoarthritic Knee Pain, Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
- Trial name
- Medial OA CSI (NCT07804446)
- Testing
- Anteromedial Injection, Anterolateral Injection
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of Chicago
Hip Disease
Evaluation of LB in THA
This study aims to compare the effectiveness of liposomal bupivacaine (LB) versus standard of practice local injection containing plain bupivacaine.
- Trial name
- NCT03341104
- Testing
- Bupivacaine liposome
- Volunteers
- 173 people
- Sponsor
- OSF Healthcare System
Breast Cancer, Triple Negative Breast Cancer
Abraxane With or Without Tigatuzumab in Patients With Metastatic, Triple Negative Breast Cancer
Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer deaths in American women. Metastatic disease including metastatic breast cancer unfortunately remains incurable.
- Conditions
- Breast Cancer, Triple Negative Breast Cancer, Stage IV Breast Cancer, Metastatic Breast Cancer
- Trial name
- NCT01307891
- Testing
- Abraxane alone, Abraxane + Tigatuzumab
- Where
- 10 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Alabama at Birmingham
Radial Artery Injury
Effect of Local Anesthesia Position of Lidocaine Injection on the Success Rate of Radial Artery Puncture Tube
Objective: To investigate the effect of lidocaine injection location on the success rate of ultrasound-guided radial artery catheterization in a single-center, randomized, controlled clinical trial.
- Trial name
- NCT06424145
- Testing
- Superior radial artery, Right side of radial artery
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ting Xu
Hepatocellular Carcinoma (HCC)
Safety and Efficacy of Metabolically Armed GPC3 CAR-T Cells Injection (Meta10-GPC3) in Patients With Unresectable Recurrent/Metastatic Hepatocellular Carcinoma
A Study of Metabolically Armed GPC3 CAR-T Cells Injection (Meta10-GPC3) in Patients with Unresectable Recurrent/Metastatic Hepatocellular Carcinoma.
- Trial name
- NCT07487402
- Testing
- Metabolically Armed GPC3 CAR-T cells
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Zhejiang University