Clinical trials: Injector
Healthy Male Subjects
A Study to Compare the Auto-injector and Pre-filled Syringe of CT-P43 in Healthy Male Subjects
This is phase 1 study to Compare the Pharmacokinetics, Safety and Immunogenicity of the Auto-injector and Pre-filled syringe of CT-P43 in Healthy Male Subjects.
- Trial name
- NCT06951828
- Testing
- CT-P43
- Where
- South Korea
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Celltrion
Diabetic Peripheral Neuropathy
Needle-Free Subcutaneous Injector and Conventional Intramuscular Injection of Mecobalamin in Diabetes Peripheral Neuropathy
The evaluation for efficacy and safety of needle-free subcutaneous injector and conventional intramuscular injection of mecobalamin for diabetic neuropathy.
- Trial name
- NCT06400888
- Testing
- needle-free subcutaneous injector for Mecbl, intramuscular injection of Mecbl
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Healthy, Obesity
A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector
The goal of this study is to find out whether different formulations of survodutide given by different delivery methods is taken up in the body in a similar way. Participants visit the study site regularly.
- Trial name
- NCT07413913
- Testing
- Survodutide formulation A, Survodutide formulation B2
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Dental Anxiety, Pain
Comparison of Five Anesthetic Delivery Systems for Palatal Infiltration
This study is a randomized clinical trial evaluating five different anesthetic delivery systems for palatal infiltration in adults undergoing maxillary molar extraction.
- Conditions
- Dental Anxiety, Pain, Dental, Palatal Anesthesia
- Trial name
- PAL-INJECT (NCT07184879)
- Testing
- Conventional Dental Syringe, Spring-Activated Syringe (PCJ, PAROJECT™), Needle-Free Jet Injector (NFI, Comfort-in™)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sercan Küçükkurt
Injection Site, Injection Site Reaction
Sorrel 25R Injector - Sorrel Clinical Study Protocol
A prospective, open-label, single-center pilot study to evaluate the performance, safety and usability of the investigational SWI Device in healthy volunteers.
- Conditions
- Injection Site, Injection Site Reaction, Injection Site Irritation
- Trial name
- NCT05221333
- Testing
- Sorrel Wearable Injector
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eitan Medical
Diabetes Mellitus
Pharmacology of Insulin Injected With Jet-injection in Diabetes
A previous study showed that absorption and glucose-lowering action of rapid-acting insulin analogues occurred twice as fast when these analogues were administered by jet injection technology rather than by conventional insulin…
- Trial name
- NCT01438632
- Testing
- jet injection device
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Radboud University Medical Center
Growth Disorders
A Canadian, Multi-centre, Observational Registry to Study Adherence and Long Term Outcomes of Therapy in Pediatric Subjects Using SAIZEN® Via Easypod™ Auto-injector for Growth Hormone Treatment
This is a Canadian, Multicentre, Observational Registry to study Adherence and Long Term Outcomes of Therapy in paediatric subjects using Easypod™ electromechanical device for growth hormone treatment from hospital and to assess…
- Trial name
- ECOS CAN (NCT01267526)
- Testing
- Easypod™
- Where
- 9 sites in Canada
- Volunteers
- 205 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Influenza Prophylaxis
Clinical Trial Assessing the Immunologic Response to a Influenza Vaccine Delivered Using an Jet Injection Device or a Needle Syringe
The primary objective of this study was to evaluate if administration of a seasonal flu vaccine using a jet injector device is comparable to traditional needle and syringe delivery for eliciting an immune response.
- Trial name
- NCT01644149
- Testing
- Stratis Jet Injector, Needle and Syringe, 2011-2012 Fluzone trivalent inactivated influenza vaccine
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Corneal Transplantation
Corneal Endothelium Delivery Instrument
The purpose of this study is to determine whether the surgical outcomes in patients undergoing Descemet's Stripping Endothelial Keratoplasty (DSEK) are improved with the use of an insertion device over the traditional forceps…
- Trial name
- NCT00874835
- Testing
- EndoSaver™ Corneal Endothelium Delivery Instrument
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ocular Systems, Inc.
Aphakia
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System
The purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
- Trial name
- NCT02418871
- Testing
- FluidVision AIOL, Cataract surgery
- Where
- 5 sites in Hungary, South Africa
- Volunteers
- 53 people
- Sponsor
- PowerVision
Crohn's Disease
An Observational Study to Assess Participant-Reported Real-World Experience of Risankizumab On-body Injector (OBI) for the Treatment of Crohn's Disease in Adult Participants in the United Kingdom (UK)
Crohn's Disease (CD) is a chronic condition that causes inflammation of the gastrointestinal tract or gut. This study will assess real-world, adult participant experience of self-injection with the risankizumab OBI.
- Trial name
- COMMODUS (NCT06126146)
- Where
- 5 sites in United Kingdom
- Volunteers
- 53 people
- Sponsor
- AbbVie
Type 1 Diabetes Mellitus, Sleep Quality
Safety and Effectiveness of the Luna System in People With Type 1 Diabetes Mellitus
The purpose of this research is to evaluate the effect of a wearable insulin pump on blood sugar levels during sleep. The study device works with continuous glucose monitors (CGM) to calculate and deliver rapid-acting insulin…
- Trial name
- AID4MDI (NCT06627517)
- Testing
- Episodic overnight patch pump
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Luna Diabetes
Plaque Psoriasis
Study of Efficacy and Safety of Secukinumab 2 mL Auto-injector (300 mg) in Subjects With Moderate to Severe Plaque Psoriasis
The primary purpose of this study is to assess efficacy, safety and tolerability of a 2 mL pre-filled auto-injector (AI) of 300 mg secukinumab in patients with moderate to severe plaque psoriasis
- Trial name
- MATURE (NCT03589885)
- Testing
- Secukinumab 2 mL auto-injector, Secukinumab 1 mL prefilled syringe
- Where
- 22 sites in United States, Canada and 4 more
- Volunteers
- 122 people
- Sponsor
- Novartis Pharmaceuticals
Handling of Auto-injectors
Comparative Evaluation of Handling Characteristics of Two Adrenaline Autoinjectors,EpiPen in Comparison With Jext
The purpose of the study is to demonstrate non-inferiority of Jext compared with EpiPen for the proportion of subjects with a successful self-injection.
- Trial name
- HEJ (NCT01887405)
- Testing
- Adrenaline auto-injector
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- ALK Nordic A/S, Danmark Filial
Varicella, Hepatitis A
Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery
This study aims to assess immunogenicity and safety of nd influence of the delivery system (needle-free injector or syringe with needle) of fractional doses (dose sparing) of two vaccines (Varicella and Hepatitis A vaccines) in…
- Trial name
- InjHepAVar (NCT00926419)
- Testing
- Varicella Vaccine, Hepatitis A Vaccine
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Health, Subjective
CT-P13 (Infliximab) Subcutaneous Administration by Pre-filled Syringe and Auto-injector in Healthy Subjects
This study compares two administration methods of CT-P13. Half of participants will receive CT-P13 by pre-filled syringe while the other half will receive CT-P13 by auto-injector.
- Trial name
- NCT03446976
- Testing
- CT-P13 SC Auto-injector, CT-P13 SC Pre-filled Syringe
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Celltrion
Inverted Nipple, Exclusive Breastfeeding
The Effect of a Developed Device for Mother With Flat or Inverted Nipples
Breast milk alone can meet all the elements necessary of babies during the first 6 months. However, some problems prevent breast milk from being taken, including concern about milk insufficiency, hyperlactation, clogged milk…
- Trial name
- NCT06978543
- Testing
- A Prototype Device Developed for Flat or Inverted Nipples (DFIN), Modified injector
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Physiological Effects of Drugs, Anesthetics
Effectiveness of the Comfort-In Needle Free Injection System During Palatal Infiltrative Anesthesia
The goal of this randomized clinical trial is to compare two different injection methods in children. The main question it aims to answer is: Is the needle-free injection method more painless than the traditional dental method?…
- Trial name
- NCT06606587
- Testing
- Comfort-in Jet Injection Method, Traditional Dental Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Non Hodgkin Lymphoma, Breast Cancer
Patient Preference for Pegfilgrastim (Neulasta®) Application Forms
The study aims to compare two application forms (pre-filled syringe and On-body injector) of the same active drug (pegfilgrastim) in adult patients under chemotherapy regarding patient preference and health economics.
- Trial name
- CONVENIENCE (NCT03619993)
- Testing
- On-body injector, Pre-filled syringe
- Where
- 48 sites in Germany
- Volunteers
- 404 people
- Sponsor
- iOMEDICO AG
Healthy Subjects
Autoinjector Device Assessment Study
Phase I study to determine the device-related injection failure rate of the single-use, pre-filled autoinjector.
- Trial name
- BCB119 (NCT02349802)
- Testing
- Auto-injector with exenatide suspension, Syringe with exenatide suspension
- Where
- 2 sites in United States
- Volunteers
- 3,052 people, healthy volunteers welcome
- Sponsor
- AstraZeneca