Clinical trials: Injuries, Head
Extracorporeal Membrane Oxygenation Complication, Acute Brain Injury
Assessing Brain Injury Using Portable Magnetic Resonance Imaging (MRI)
This study aims to assess the feasibility of assessing acute brain injury using a portable low field MRI in patients on ECMO.
- Trial name
- SAFE MRI (NCT05469139)
- Testing
- Portable MRI acquisition
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Post-Concussion Symptoms
Testing of a New Computer Screen for Patients With Persistent Concussion Symptoms (PCS).
This study will examine whether a newly designed monitor for computers is better tolerated by concussed patients than the standard computer monitor.
- Trial name
- NCT05660057
- Testing
- New computer monitor
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Acquired Brain Injury, Cerebral Palsy
Verify the Performance in Clinical Practice of the Immersive Virtual Reality Platform GRAIL (Gait Real-time Analysis Interactive Lab)
Gait pattern difficulties, balance and coordination deficits often characterize patients with congenital and acquired neuromotor disorders and have a significant impact on the quality of life of these subjects.
- Trial name
- NCT06317519
- Testing
- Physical Rehabilitation, Gait Real-time Analysis Interactive Lab
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Mild Concussion, Post Concussion Syndrome
Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool
The iDETECT (Integrated Display Enhanced Testing for Concussion and mild traumatic brain injury) system is a novel portable, open access platform that enables immediate and rapid assessment of multimodal neurologic function.
- Conditions
- Mild Concussion, Post Concussion Syndrome, Vestibular Neuritis
- Trial name
- NCT02171312
- Testing
- iDETECT Assessment, Routine Balance and Vestibular Testing
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Emory University
Brain Injuries, Stroke
Telerehabilitation in Severe Acquired Brain Injury
We will investigate the use of TR, based on advanced Information and Communication Technology (ICT) solutions, taking into account that the supervision of rehabilitation at home will be enriched with the counselling and vital…
- Trial name
- NCT03709875
- Testing
- TR Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Acquired Brain Injury (Including Stroke)
Clinical Investigation to Validate the Safety and Performance of the ABLE Exoskeleton Device for Individuals With Acquired Brain Injury in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Exoskeleton device in people with acquired brain injury during a 10-session gait training program in a clinical setting.
- Trial name
- NCT07050875
- Testing
- ABLE Exoskeleton
- Where
- 3 sites in Spain
- Volunteers
- 14 people
- Sponsor
- ABLE Human Motion S.L.
Traumatic Brain Injury, Dementia Alzheimers
Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury
Patients with a history of traumatic brain injury (TBI) are at elevated risk for Alzheimer's disease and related dementias (ADRD). Improvements in TBI treatment may mitigate this risk.
- Conditions
- Traumatic Brain Injury, Dementia Alzheimers, Military Activity
- Trial name
- OCEANS-TBI (NCT04073225)
- Testing
- MindPod Dolphin, 10 Keys to Healthy Aging
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Johns Hopkins University
Head and Neck Cancer
Safety Study of Musculoskeletal Ultrasonographic to Assess Disabilities Arm of Head and Neck Cancer Patient
The investigators suppose: 1. SND may cause damage to the soft tissue around shoulder girdle. 2. The soft tissue injury may be related with the order of severity of wing scapula and duration after SND.
- Trial name
- NCT02369276
- Testing
- ultrasonography and elastography
- Where
- Taiwan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Radial Fracture
Brace Versus Casting in Pediatric Radial Head Fractures
Commare the pain and function of Brace Versus Casting in Pediatric Radial Head Fractures after 1 month
- Trial name
- NCT03360318
- Testing
- elbow cast, Removable elbow brace
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University People's Hospital
Depression, Closed Head Injury
TMS in the Treatment of the Sequelae of Closed Brain Injury
Depression is very common in people who have experienced a traumatic brain injury. Few treatments have been found to be effective in treating depression in this situation.
- Trial name
- NCT00531258
- Testing
- rTMS
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Bayside Health
Xerostomia, Radiation-induced Parotid Damage,Predictivevalue,Head and Neck Cancer
Prospective Study on Monitoring Parotid Gland Injury After Radiotherapy for Head and Neck Tumors Using Multimodal Radiomics
Exploring a non-invasive and objective method for ultra early quantitative assessment of radiation-induced parotid gland injury.
- Trial name
- NCT06792526
- Testing
- IVIM Imaging MRF Imaging
- Volunteers
- 20 people
- Sponsor
- Hainan People's Hospital
Traumatic Brain Injury, Substance Abuse
Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)
This is a placebo-controlled study intended to examine the effects of the neutraceutical citicholine, together with omega-3 fatty acids, on a range of measures in individuals with concussive head injury, often referred to as…
- Conditions
- Traumatic Brain Injury, Substance Abuse, Substance Dependence
- Trial name
- NCT01515917
- Testing
- Citicoline, Omega-3, Rice bran oil
- Sponsor
- Deborah Yurgelun-Todd
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
Concussion, Mild Traumatic Brain Injury
Interhemispheric Anterior Delta Desynchronization in Children Who Present to the Emergency Department With Acute Concussion: A Proof of Concept Study
Approximately 150,000 children present each year to emergency departments (EDs) in the US with concussion and many more are treated by primary care physician, or outpatient specialists.
- Trial name
- NCT02916108
- Testing
- Reading EEG
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Concussion (Diagnosis)
Sports-related Concussion: Physiological, Biomechanical and Cognitive Methodology
The study aims to investigate the changes in physiological, biomechanical and cognitive performance under a traumatic sport-event (i.e., rugby match).
- Trial name
- NCT04841876
- Testing
- rugby matches
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Multiple Trauma, Traumatic Brain Injury
Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient
The Alfred Hospital receives approximately 40% of the major trauma patients in Victoria, all of whom are at risk for spinal injuries.
- Conditions
- Multiple Trauma, Traumatic Brain Injury, Spinal Injuries
- Trial name
- NCT00163826
- Where
- Australia
- Volunteers
- 299 people
- Sponsor
- Bayside Health
Brain Injury
Motivation and Self-awareness in Acquired Brain Injury (ABI)
Acquired Brain Injury (ABI) is damage to the brain caused by a head injury or illness/disease such as stroke or aneurysm. ABI is often associated with poor awareness into ongoing symptoms of damage to the brain, which can be…
- Trial name
- NCT02913755
- Testing
- Preparatory video
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Glasgow
Severe Traumatic Brain Injury
The Systemic Nature of Severe Traumatic Brain Injury
Severe traumatic brain injury (sTBI) is a devastating condition with no targeted therapies available to prevent secondary injury.
- Trial name
- MANTRA (NCT07679126)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Corewell Health West
Traumatic Brain Injury, Brain Concussion
Ondansetron for Pediatric Mild Traumatic Brain Injury
Background: Most patients suffering from mild Traumatic Brain Injury (mTBI) present persistent symptoms at one week post injury. A systematic review showed a paucity of studies for short term outcomes following mTBI.
- Trial name
- NCT01815125
- Testing
- Ondansetron
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- St. Justine's Hospital
Traumatic Brain Injury
Salivary Biomarkers in Pediatric Traumatic Brain Injury
By studying individual biomarkers in body fluids such as saliva, there is a potential for detecting injury to the brain resulting from an acute traumatic even that may not be detectable by conventional neuroimaging like CT scans.
- Trial name
- NCT02609568
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Valleywise Health