Clinical trials: Injuries, Knee
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
The purpose of this study is to compare the effects of a femoral nerve block vs. an adductor canal block on pain and quadriceps muscle strength for knee arthroscopy surgery.
- Trial name
- NCT05190120
- Testing
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Knee Pain Chronic, Anterior Knee Pain Syndrome
Clinical Applications of Blood Flow Restriction and Rehabilitation Outcomes
The study aims to evaluate the effect of low load resistance training combined with blood flow restriction or sham blood flow restriction in patients with anterior knee pain and rotator cuff related shoulder pain in a cross-over…
- Conditions
- Knee Pain Chronic, Anterior Knee Pain Syndrome, Patellofemoral Pain Syndrome, Rotator Cuff Impingement Syndrome
- Trial name
- NCT04989023
- Testing
- Blood flow restriction (BFR) with low load resistance training
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Aspetar
Knee Dislocations, Multiple Ligament Knee Injuries
STaR Trial: Multiple Ligament Knee Injuries
The purpose of this study is to investigate effects of timing of surgery (early vs. delayed) and timing of post-operative rehabilitation (early vs.
- Trial name
- NCT03543098
- Testing
- Early Surgery, Delayed Surgery, Early Rehab
- Where
- United States
- Volunteers
- 690 people
- Sponsor
- University of Pittsburgh
Ankle Joint Contracture, Knee Injuries and Disorders
Immediate Effects of Two Ankle Mobilization Techniques in the Amplitude of Dorsiflexion and Dynamic Valgus Knee
Dynamic knee valgus is an inadequate biomechanical movement of multifactorial cause that may expose the individual to various injuries. The range of motion of ankle dorsiflexion is one of the possible influencing factors.
- Trial name
- NCT03171233
- Testing
- Mobilization with movement, Self mobilization with movement
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Knee Injuries, Shoulder Injuries
Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
The investigators have previously reported on patient utilization of an eRehab patient education web portal that utilizes streaming, clinician prescribed video instruction to motivate and inform patients in self-care of their…
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear
- Trial name
- NCT02025400
- Testing
- eRehab, Formal Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charlotte Sports Medicine Institute, PA
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction
Randomized control trial comparing two different Anterior Cruciate Ligament (ACL) grafts in Anterior Cruciate Ligament Reconstruction: the semitendinosus hamstrings graft and the quadriceps graft.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- SEQUAR (NCT04295148)
- Testing
- ACL Reconstruction with Semitendinosus graft, ACL Reconstruction with Quadriceps tendon-bone graft
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anterior Cruciate Ligament Rupture
Follow-up of Anterior Cruciate Ligament Reconstruction
Rupture of Anterior Cruciate Ligament (ACL) is a common pathology, but is subject to variability of associated lesions, surgical management and rehabilitation.
- Trial name
- NCT04781920
- Testing
- datas collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Knee Injuries
Validity and Reliability in Measuring Iliotibial Tract by Using Ultrasound
The purpose of this study is to estimate the validity and reliability in measuring the iliotibial tract by using ultrasound.
- Trial name
- NCT00174213
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Anterior Cruciate Ligament Injuries
Efficacy of Adductor Canal Block for Anterior Cruciate Ligament Surgery
The goal of this study is to objectify the postoperative pain level, the use of opiates and postoperative nausea and vomiting after adding the adductor canal block to the standard pain regiment after anterior cruciate ligament…
- Trial name
- DUAL (NCT05532618)
- Testing
- Adductor canal block, Levobupivacaine
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Anterior Cruciate Ligament Injury
Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of anterior cruciate ligament reconstruction: a treatment…
- Trial name
- NCT03818932
- Testing
- Celecoxib, Hydrocodone-Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Rupture, Ligament Knee Injury
Association of ALL and ACL Reconstruction Versus Isolated ACL Reconstruction in High-risk Population: a RCT.
Persistent rotational instability after standard ACL reconstruction have been extensively described, and it has been shown to keep straight correlation with worse outcomes post-operatively (Chouliaras 2007, Kocher 2004).
- Trial name
- NCT03229369
- Testing
- Isolated anatomic ACL reconstruction, Combined Anterior Cruciate Ligament and Anterolateral Ligament reconstruction
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Bursitis, Tendinitis
Efficacy and Safety of Etoricoxib/Betamethasone Combination in Acute Bursitis, Tendinitis and Synovitis
Phase III, multicenter, prospective, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of a fixed-dose combination of etoricoxib/betamethasone compared with etoricoxib alone in patients with an…
- Conditions
- Bursitis, Tendinitis, Synovitis
- Trial name
- NCT07328022
- Testing
- Fixed Dose Etoricoxib + Betamethasone, Monotherapy Etoricoxib
- Where
- Mexico
- Volunteers
- 89 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Sprain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Transdel Pharmaceuticals is investigating a topical cream formulation consisting of 10% ketoprofen for the local treatment of pain associated with mild to moderate acute soft tissue injury in this confirmatory Phase 3 trial.
- Trial name
- NCT01223053
- Testing
- Ketoprofen 10% cream
- Sponsor
- Imprimis Pharmaceuticals, Inc.
ACL Injury
The Single Leg Squat Test to Evaluate Dynamic Knee Stability After ACLR
Patients with anterior cruciate ligament (ACL) injury often suffer knee instability, which can be visualized as a wobbling knee during weight bearing exercises, such as the single leg squat.
- Trial name
- NCT05294783
- Testing
- ACL reconstruction
- Where
- Hong Kong
- Volunteers
- 43 people
- Sponsor
- Chinese University of Hong Kong
ACL, ACL Injury
Evaluation Of Clinical Results And Imaging Of Anterior Cruciate Ligament Reconstruction With Orthopure Xt
The purpose of this study is to evaluate subjective and objective clinical outcomes and imaging data of subjects undergoing reconstruction or revision of LCA reconstruction using OrthoPure XT
- Trial name
- NCT06091488
- Testing
- Orthopure
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Istituto Ortopedico Rizzoli
Low Back Pain, Radicular Syndrome
Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders
This pilot randomized controlled trial aims to compare the clinical effectiveness of advanced high-intensity physical therapy modalities with conventional physical therapy in patients suffering from musculoskeletal disorders.
- Conditions
- Low Back Pain, Radicular Syndrome, Sacroiliac Joint Dysfunction, Shoulder Impingement Syndrome
- Trial name
- NCT07903142
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS), High-Intensity Laser Therapy (HIL), Extracorporeal Shockwave Therapy (ESWT)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- BTL Industries Ltd.
Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral)
Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern.
- Conditions
- Total Knee Anthroplasty, Venous Insufficiency (Chronic)(Peripheral), Doppler Ultrasound Diagnosis
- Trial name
- VENOUS-TKA (NCT07577141)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- SB Istanbul Education and Research Hospital
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Patellar Dislocation
Predicting Factors for the Outcome of Surgical Treatment for Patellar Instability
The purpose of the study is: 1. to analyze the success of operative stabilization of the patellar joint with the reconstruction of the medial patellofemoral ligament (MPFL) in terms of the subjective status of the knee, the…
- Trial name
- MPFL (NCT04673188)
- Testing
- Reconstruction of MPFL with or without tibial tuberositas osteotomy
- Where
- Slovenia
- Volunteers
- 145 people
- Sponsor
- Nik Žlak
Necrosis of Femoral Head, Knee Osteoarthritis
Probiotics Attenuate Postoperative Cognition Decline
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Neck of Femur, Lumbar Disc Herniation
- Trial name
- NCT04017403
- Testing
- Bifidobacterium triple live capsule
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
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