Clinical trials: Injuries, Knee
Anterior Cruciate Ligament Injuries
Cartilage Injury and Remodeling After ACL Rupture and Reconstruction: Functional Imaging and Biomarkers
The proposed study will establish novel relationships between intra-articular MSC recruitment, synovial inflammation, biomarkers of cartilage degeneration and joint inflammation, clinical patient factors, and downstream…
- Trial name
- NCT04970706
- Testing
- ACL reconstruction
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Ankle Injuries, Femoral Neck Fractures
Clinical Use of Andante SmartStep System in Gait Rehabilitation
The purpose of this study is to evaluate the effectiveness of the biofeedback gait training device in improving load bearing over an operated limb, during post-operative gait training therapy.
- Trial name
- NCT00268658
- Testing
- SmartStep(tm) biofeedback device
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Amputation, Surgical, Amputation, Traumatic
Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation
When a limb is severed, pain perceived in the part of the body that no longer exists often develops and is called "phantom limb" pain.
- Conditions
- Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
- Trial name
- NCT06071715
- Testing
- ACTIVE cryoneurolysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Knee Osteoarthritis, Postoperative Pain
Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty
This randomized, double-blind comparative study evaluates postoperative analgesic efficacy and motor effects of ultrasound-guided para-sartorial compartments (PASC) block versus ultrasound-guided combined femoral-sciatic nerve…
- Conditions
- Knee Osteoarthritis, Postoperative Pain, Total Knee Arthroplasty
- Trial name
- NCT07320833
- Testing
- Ultrasound-Guided Femoral Nerve Block plus Sciatic Nerve Block, Ultrasound-Guided Para-sartorial Compartments Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ain Shams University
Reliability in the Detection of ACL Injuries in Emergency Departments
Evaluation of the External Validity of the Knee SFA Score
A screening score for ACL (anterior cruciate ligament) injuries based on questioning has been developed by the Société Francophone d'Arthroscopie to provide better guidance for post-trauma patients.
- Trial name
- SCORESFA (NCT06960681)
- Testing
- External validity of the SFA score
- Where
- 3 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Rouen
PCL
Rehabilitation of Patient With Acute Isolated PCL Rupture
The posterior cruciate ligament injuries (PCL) is rare and rehabilitation methods are varying. The purpose of the study is to explore if one rehabilitation option is preferable to one other for patients with acute PCL injury, by…
- Trial name
- NCT02974205
- Testing
- Jack brace, Rehabilitation, össur brace
- Where
- 2 sites in Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ligament Injury
Peroneus Longus Graft :Effect in Foot and Ankle Function
The purpose of this study is to report the ankle and foot functions via American orthopedic foot and ankle society score (AOFAS), peronei muscle testing ,handheld dynamometer and radiological outcomes after harvesting autogenous…
- Trial name
- NCT05991557
- Testing
- peroneus longus autograft
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Injuries
Anterior Tibial Subluxation in the Setting of ACL-injury and After ACL Reconstruction
To identify the related factors for anterior tibial subluxation (ATS) on anterior cruciate ligament-injured MRI images.
- Trial name
- NCT04956536
- Testing
- Demographic data and MRI images were extracted and analyzed
- Where
- China
- Volunteers
- 297 people
- Sponsor
- Peking University Third Hospital
Anterior-cruciate Ligament Knee Injury
Utilization of Rehabilitation Prior to Surgery Among Patients With Anterior-cruciate Ligament Knee Injury
This research aims to assess physiotherapy utilization in the treatment of patients with an anterior-cruciate ligament knee injury, when delivered before their surgery (prehab), and its potential effects on absence from work, and…
- Trial name
- prehab-ACL (NCT05737719)
- Testing
- Rehabilitation before knee surgery (prehab), Post-surgery rehabilitation
- Where
- France
- Volunteers
- 864,000 people
- Sponsor
- Nantes University Hospital
ACL Injury
The Effect of Movement Education on Jumping/Landing Quality in High School Athletes
While much evidence exists to support the association between physical training and improved motor skill performance, there is little evidence that supports the association between movement education and improved motor skill…
- Trial name
- NCT04342000
- Testing
- Movement education workshop
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Distal Femur Fracture, Tibial Plateau Fracture
Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
The overall objective of this study is to compare outcomes following early advanced weight bearing (EAWB) using the AlterG antigravity treadmill versus standard of care physical therapy for adult patients with lower extremity…
- Conditions
- Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
- Trial name
- AlterG (NCT03562364)
- Testing
- AlterG anti-gravity treadmill
- Where
- 10 sites in United States
- Volunteers
- 81 people
- Sponsor
- Major Extremity Trauma Research Consortium
Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Quadriceps Tendon vs Hamstring Tendon Autograft - A Prospective RCT
A prospective randomized controlled trial comparing functional outcomes of arthroscopic anterior cruciate ligament reconstruction using quadriceps tendon autograft versus hamstring tendon autograft at SMS Medical College, Jaipur.
- Trial name
- NCT07470944
- Testing
- Arthroscopic ACL Reconstruction
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sawai Mansingh Medical College
Knee Osteoarthritis, Knee Injuries
Evaluation of Clinical Outcomes of Scaffold Treatment of Partial Meniscal Injuries of the Knee
The study consists of 3 phases (Identification of includable patients, Telephone follow-up evaluation and the collection of study-specific clinical data in medical records of enrolled patients): Identification by trained medical…
- Conditions
- Knee Osteoarthritis, Knee Injuries, Meniscus Lesion
- Trial name
- STAR-ACT (NCT06475963)
- Testing
- surveys
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Collateral Ligament Injury of Stifle Joint
Effectiveness of Hydrolyzed Collagen Peptide Injection for the Treatment of Collateral Ligament Pain
Conducted by Binh Luu Thi, Lan Tran Thi, and Minh Hang Hoang Thi at Thai Nguyen National Hospital, the study investigates a new approach to treating persistent collateral ligament pain, common among athletes.
- Trial name
- NCT05971004
- Testing
- Arthrys (Collagen Peptide solution), Depo medrol
- Where
- San Marino
- Volunteers
- 62 people
- Sponsor
- Tiss'You srl
Hip Fractures, Knee Fracture
Evaluation of Multidisciplinary Recovery After Surgery Program in Orthopedics and Traumatology
The aim of the recovery protocol is to reduce surgical trauma, postoperative pain, and complications, shorten hospital treatment and improve postoperative recovery.
- Conditions
- Hip Fractures, Knee Fracture, Hip Arthritis, Knee Arthritis
- Trial name
- NCT03822247
- Testing
- Multidisciplinary Recovery Program
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Total Knee Arthroplasty, Infection
Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty
The study's primary objective is to compare the following parameters between wound closure following primary TKA with and without supplement tissue adhesive (Leukosan®):
- Conditions
- Total Knee Arthroplasty, Infection, Arthroplasty Complications
- Trial name
- NCT03289247
- Testing
- tissue adhesive (Leukosan®)
- Volunteers
- 30 people
- Sponsor
- Hvidovre University Hospital
Anterior Cruciate Ligament Injuries
Dynamic Muscular Electrical Stimulation Following Anterior Cruciate Ligament Reconstruction in Military Academy Cadets
The goal of this clinical trial is to examine the effects of 12 weeks of post-operative use of a novel wearable electrical stimulation knee sleeve device (KneeStim) on post-operative biomechanical function (gait).
- Trial name
- NCT06341868
- Testing
- KneeStim
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Keller Army Community Hospital
Peripheral Artery Disease, Vascular Disease
Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Patients scheduled for major extremity lower amputation to receive bone marrow cells (cBMA) injected IM in the leg proximal to the amputation in the index limb to prevent ischemic wound complications after surgery.
- Conditions
- Peripheral Artery Disease, Vascular Disease, Critical Limb Ischemia
- Trial name
- MarrowCHAMP (NCT02863926)
- Testing
- Injection of cBMA aspirate into the index leg
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Michael Murphy
ACL Injury
ADC in Assessing Femoral Tunnel Position
To examine the consistency between postoperative CT scan and intraoperative arthroscopic measurement in evaluating femoral tunnel position for anterior cruciate ligament （ACL）reconstruction，both using the apex of the deep…
- Trial name
- NCT04937517
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament (ACL) Revision Surgery: French National Study
This is a national multicentric study led by the French Arthroscopy Society (SFA) evaluating clinical practice in anterior cruciate ligament (ACL) revision surgery (epidemiological data, morphological data, operative data…
- Trial name
- NCT06379308
- Testing
- questionaries, datas of medical record
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
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