Clinical trials: Injuries, Knee
Knee Injuries and Disorders
Recovery of Soccer Players After Anterior Cruciate Ligament Reconstruction.
The purpose of this CRT study is to compare clinical and functional outcomes of three graft types ( Quadriceps tendon with bone versus Hamstring tendon versus Quadriceps tendon without bone) for reconstration of anterior cruciate…
- Trial name
- NCT04742868
- Testing
- ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH QUADRICEPS TENDON WITH BONE GRAFT, ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH HAMSTRING TENDON GRAFT, ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH QUADRICEPS TENDON WITHOUT BONE GRAFT
- Where
- 2 sites in Spain
- Volunteers
- 74 people
- Sponsor
- Universidad de Granada
ACL Reconstruction, Tenodesis
Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee joint, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL Reconstruction, Tenodesis, ACL Injuries
- Trial name
- LETOTT (NCT07049484)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Stefano Zaffagnini
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Depression, Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
The goal of this parallel arm prospective randomized control trial study is to compare outcomes in Anterior Cruciate Ligament Reconstruction (ACLR) Surgery patients after exposure to a virtual psychological intervention (VPI)…
- Conditions
- Depression, Anterior Cruciate Ligament Injuries, Mental Health Issue
- Trial name
- NCT05965310
- Testing
- Virtual Psychological Intervention: Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Henry Ford Health System
Sport Injury, Osteoarthritis, Knee
Biometric Recognition and Rehabilitation Assessment of Lower Extremity Sports Injury Based on Gait Touch Information
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. Based on the foot-knee coupling mechanism, the simple and practical dynamic gait touch information provided by the 3D force…
- Trial name
- NCT04462913
- Testing
- no intervention
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Gonarthrosis; Primary, Degenerative Joint Disease of Knee
The Effect of Three Prosthesis Designs in Total Knee Arthroplasty
The purpose of this study is to compare three prosthesis designs to compare three prosthesis designs for total knee arthroplasty and determine the best option for patients in need of a knee replacement.
- Trial name
- NCT03059927
- Testing
- Knee arthroplasty, Cruciate retaining, Knee arthroplasty, Anterior stabilized, Knee arthroplasty, Posterior stabilized
- Where
- 2 sites in Norway
- Volunteers
- 216 people
- Sponsor
- Lovisenberg Diakonale Hospital
Anterior Cruciate Ligament Injuries
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
Anterior cruciate ligament (ACL) injuries are extremely common. On average, 50% of individuals suffering an ACL injury will develop radiographic osteoarthritis (OA) 10 to 20 years after injury.
- Trial name
- NCT03968913
- Testing
- Anakinra injection, sterile saline injection
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anterior Cruciate Ligament Injuries
Reduce Opiate Exposure With ACL Surgery
This is a randomized control trial to investigate the effectiveness of a multimodal opiate sparing analgesic regimen in controlling post-operative pain and potentially reduce post-operative opioid consumption in patients…
- Trial name
- NCT06561035
- Testing
- Opiate Sparing, Opiate Based
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Campbell Clinic
Knee Injuries
Comparison of Different Treatment Methods in Patella Chondromalacia
Chondromalacia patella (CMP) is a common condition in patients presenting to healthcare units with anterior knee pain (1).
- Trial name
- NCT06420882
- Testing
- The experimental group., The home exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Anterior Cruciate Ligament Injury
Single- vs. Double-Bundle ACL Reconstruction
The purpose of this double-blind, randomized clinical trial to compare outcomes of single-bundle (SB) to anatomic double-bundle (DB) ACL reconstruction.
- Trial name
- NCT01319409
- Testing
- Anatomic Double-Bundle ACL Reconstruction, Anatomic Single-Bundle ACL Reconstruction
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
ACL Tears
MRI Evaluation of Graft Maturation Following ACL Reconstruction
Post-surgical ACL Graft maturation will be assessed at 4.5, 6, 7.5, 9, 10.5, and 12 months with MRI.
- Trial name
- NCT07046000
- Testing
- MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Skye Biologics Holdings, LLC
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anterior Cruciate Ligament Injuries
Multiple Instrumentation for ACL Reconstruction Regarding Bacterial Contamination
To determine the Effect of multiple instrumentation regarding bacterial contamination in transportal and transtibial techniques in ACL reconstruction .A Randomized controlled study
- Trial name
- NCT04100837
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Arthroplasty, Replacement, Knee
Postoperative Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain. Although epidural treatment provides good and reliable postoperative pain relief after THA, it may cause urinary retention, nausea…
- Trial name
- NCT00421967
- Testing
- Ropivacaine, Ketorolac, adrenaline, Ropivacaine Ketorolac
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Hamstring Tightness, Hamstring Injury Prevention
The Effectiveness of Muscle Energy Technique and Friction Massage in Hamstring Tightness Amongst Young Athletes of Pakistan
The ability of an individual to move smoothly depends on his flexibility, an attribute that enhances both safety and optimal physical activity.
- Trial name
- NCT03680300
- Testing
- Post Facilitation Stretch, Post Isometric Relaxation, Friction Massage
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isra University
Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation
People with leg amputations often experience daily changes in the size (volume) of their residual limb. These daily changes can cause a prosthesis to fit poorly. They can also cause limb problems like pain or skin breakdown.
- Trial name
- NCT05124652
- Testing
- Auto Adjusting Prosthesis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anterior Cruciate Ligament Injuries
Neuromuscular Training on Lower Extremity in Post-operative Anterior Cruciate Ligament Reconstruction
The objective of the study was to determine the effectiveness of neuromuscular physical Therapy as compared to strength training after ACL reconstruction in terms of pain, function, quality of life, strength and power of…
- Trial name
- ENTACLR (NCT04355078)
- Testing
- Neuromuscular Training, Strength Training
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Riphah International University
Femoral Neck Fractures, Hemiarthroplasty
Uncemented Hemiarthroplasty, Radiological Features Comparing Lateral Versus Anterolateral Approach
Uncemented Hemiarthroplasty, Radiological Features Comparing Lateral Versus Anterolateral Approach. Comparing leg length discrepancy, femoral offset, valgus/varus position of the stem.
- Conditions
- Femoral Neck Fractures, Hemiarthroplasty, Heterotopic Ossification
- Trial name
- NCT03974698
- Testing
- Hemiarthroplasty
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sorlandet Hospital HF
Tendinopathy
Treatment of Acute and Chronic Ligament and Tendon Injuries With Platelet Rich Plasma
Platelet rich plasma has been used in previous studies to stimulate faster healing of torn ligaments and tendons in order to help reduce pain and restore normal function.
- Trial name
- NCT01406821
- Testing
- Ultrasound-guided platelet-rich-plasma (PRP) injection, Ultrasound-guided dry needling
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
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