Clinical trials: Injuries, Knee
Anterior Cruciate Ligament Tear
Evaluation of Biocleanse Allografts For ACL Reconstruction
The purpose of this study is to determine the efficacy of patellar tendon allografts that have undergone the BioCleanse™ process.
- Trial name
- NCT00187876
- Testing
- ACL reconstruction control, ACL Biocleanse, surgical
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Florida
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
ACL Reconstruction, ACL Injury
Validity of the SHD-LESS Scale After ACL Reconstruction
After anterior cruciate ligament reconstruction (ACL-R), Single Hop for Distance (SHD) performance aids in decision-making, particularly for return-to-sport assessments.
- Trial name
- ACL-LESS (NCT06829849)
- Testing
- Landing error assessment during a SHD task using the SHD-LESS scale
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Telerehabilitation, Anterior Cruciate Ligament Injuries
Telerehabilitation for Anterior Cruciate Ligament Reconstruction - TAR Program in Adolescents
Anterior cruciate ligament (ACL) injuries are common in adolescents and its prevalence has increased over the years, especially with more adolescents engaging in physical activities and competitive sports.
- Conditions
- Telerehabilitation, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament
- Trial name
- TAR (NCT05799235)
- Testing
- Telerehabilitation TAR program using a mobile application, Standard rehabilitation sessions
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Meniscal Tears
Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study
This prospective, randomized, comparative clinical study will evaluate the clinical and functional outcomes of meniscal repair augmented with intraoperative intralesional leukocyte-poor platelet-rich plasma (LP-PRP) compared with…
- Trial name
- NCT07815743
- Testing
- Leukocyte-poor platelet-rich plasma, Meniscal Repair
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Knee Injuries
Acute Pain and Inflammation After Surgery
The purpose of this study is 1. to observe acute pain after surgery and measure the natural course of inflammatory mediators 2. study pain relieving effects and local anti-inflammatory effects of systemically administered…
- Trial name
- Knemikro01 (NCT00774540)
- Testing
- 1 Ketorolac intraarticular
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Knee Injuries and Disorders, Hip Injuries and Disorders
Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
The purpose of this study is to evaluate the use of post-operative opioid use after two different educational interventions. The investigators will compare changes in pain, disability and sleep between groups 6 months after…
- Conditions
- Knee Injuries and Disorders, Hip Injuries and Disorders, Opiate Addiction
- Trial name
- OpiateLEO (NCT02997644)
- Testing
- Video Education, Usual Care Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Total Knee Replacement
Comparison of Surgical Site Infection After Skin Closure by Prolene or Staples in Bilateral Knee Arthroplasty Patients
Knee arthroplasty also known as the total knee replacement is an orthopedic surgical procedure done to resurface the knee that has been severely damaged by arthritis.
- Trial name
- NCT04492852
- Testing
- Polypropylene (PROLENE) sutures, Staple Sutures
- Volunteers
- 82 people
- Sponsor
- Indus Hospital and Health Network
Injuries, Injury Arm
Virtual Reality for Pain in Acute Orthopedic Injuries
The goal of this study is to pilot test a skills-based virtual reality (VR) for acute orthopedic injury. It will measure the feasibility, signals of improvement, exploratory pain mechanisms, and user experience of an established…
- Conditions
- Injuries, Injury Arm, Injury;Sports, Injury, Knee
- Trial name
- NCT05552430
- Testing
- RelieveVRx
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Anterior Cruciate Ligament Injuries
Rate of Non-copers to Non-surgical ACL Treatment After 3 Months of Rehabilitation
The aim is to determine the sensitivity and specificity of a screening tool to identify patients who undergo ACL reconstruction (non-copers) after 3 months of standard rehabilitation following an anterior Cruciate ligament (ACL)…
- Trial name
- NCT04847258
- Testing
- Standard rehabilitation
- Where
- Denmark
- Volunteers
- 357 people
- Sponsor
- Vejle Hospital
ACL Injury
Effect of Contralateral NMES on Quadriceps Activation After ACL Injury or Surgery
A major complication after cruciate ligament injury and surgery is arthrogenic muscle inhibition of the quadriceps, which is characterised by a deficit in voluntary muscle activation in the affected leg.
- Trial name
- ACLQuadAct (NCT07156734)
- Testing
- Neuromuscular Electrical Stimulation
- Volunteers
- 25 people
- Sponsor
- Schulthess Klinik
Blood Flow Restriction, ACL Tear
Blood Flow Restriction Training (BFR) in an Adolescent Population
While there are a number studies that have reported on the use of BFR in the adult population, there is limited information about the use of BFR in the adolescent population.
- Conditions
- Blood Flow Restriction, ACL Tear, ACL Injury
- Trial name
- NCT04285879
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Connecticut Children's Medical Center
Anterior Cruciate Ligament Tear
Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis
The investigators aimed to compare the clinical results of primary repairs and Lateral Extraarticular Tenodesis applied with primary repairs in the treatment of proximal ACL tears.
- Trial name
- NCT05923710
- Testing
- Primary anterior cruciate ligament repair, Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injuries
External Focus of Attention Feedback to Reduce Risk of Non-contact ACL Injury
Knee injuries, especially those to the ACL, are common among physically active people. Preventing these injuries from happening is critical to limiting the long-term pain, disability, and arthritis associated with these injuries.
- Trial name
- NCT04914689
- Testing
- Internal focus of attention feedback, Visual internal focus of attention feedback, Auditory external focus of attention feedback
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Charlotte
Knee Arthropathy, Hip Arthritis
Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations.
Aim of the study is to specify the best analgosedation technique during placement of regional anaesthesia from the patients' view.
- Conditions
- Knee Arthropathy, Hip Arthritis, Fractures, Closed
- Trial name
- NCT04026074
- Testing
- Fentanyl, Remifentanil, Clonidine
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Anterior Cruciate Ligament Rupture, Electroencephalography
Functional Connectivity After Anterior Cruciate Ligament Reconstruction
Background: Despite surgical reconstruction and rehabilitation, individuals after a primary anterior cruciate ligament injury have a significantly increased risk of relapse.
- Conditions
- Anterior Cruciate Ligament Rupture, Electroencephalography, Injuries
- Trial name
- FCACLR (NCT05487768)
- Testing
- EEG measurement
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Amputation, Lower Limb Amputation Above Knee (Injury)
Evaluation of a Microprocessor-controlled Prosthetic Knee-ankle System (SPCM)
The main aim of this study is to compare the adaptation capabilities of the microprocessor-controlled knee-ankle prosthesis system with the comparator covered by the French LPPR, known as the "usual prosthesis".
- Trial name
- SPCM (NCT06522646)
- Testing
- SPCM, Usual Prothesis
- Where
- 4 sites in France
- Volunteers
- 12 people
- Sponsor
- Institution Nationale des Invalides
Sports Injury, Orthopedic Disorder
Training of Falling Techniques on Landing Mechanics
The overall purpose of this study is to quantify the effect and retention of one-week training of falling techniques on landing biomechanics associated with anterior cruciate ligament (ACL) loading compared to soft-landing…
- Conditions
- Sports Injury, Orthopedic Disorder, Knee Injuries, Anterior Cruciate Ligament Injuries
- Trial name
- NCT04768088
- Testing
- Falling Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Schatzker Type 2 or 3 Tibial Plateau Fracture
Comparative Evaluation of Minimally Invasive "tibial Tuberoplasty" Surgical Technique Versus Conventional Open Surgery for Tibial Plateau Fractures
PMSI (French Medico-Administrative Database) data shows more than 10000 proximal tibial fractures diagnosed in 2014 and 4055 lateral tibial plateau fractures operated in 2013 in France.
- Trial name
- TUBERIMPACT (NCT03444779)
- Testing
- Tibial Tuberoplasty, Open technique
- Where
- 12 sites in France, Martinique
- Volunteers
- 137 people
- Sponsor
- Poitiers University Hospital
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