Clinical trials: Injuries, Knee
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Cartilage Injury, Knee Injuries
7T MRI to Evaluate Cartilage Defects in the Knee
The investigators propose to prospectively evaluate the accuracy of a novel 7-Tesla (7T) knee MRI protocol for the detection and grading of cartilage lesions in the knee, which is a significant limitation of current MRI…
- Conditions
- Cartilage Injury, Knee Injuries, Arthropathy of Knee, Cartilage Damage
- Trial name
- NCT04118023
- Testing
- 7 Tesla Magnetic Resonance Imaging Test
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- The Methodist Hospital Research Institute
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament Injury Prevention Protocol in Female Football Players With Dynamic Knee Valgus
Introduction: Women's football has experienced exponential growth over the last ten years. Its popularity is associated with an increase in anterior cruciate ligament injuries (ACL).
- Trial name
- NCT06083818
- Testing
- Application of an anterior cruciate ligament injury prevention protocol for female football players with dynamic knee valgus for 12 weeks.
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Amanda Coves García
Wound of Skin, Non-melanoma Skin Cancer
Efficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical Defects
Large full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to patients and physicians.
- Conditions
- Wound of Skin, Non-melanoma Skin Cancer, Skin Graft Complications, Wound of Lower Leg
- Trial name
- NCT03548610
- Testing
- Nanofat-seeded biological scaffold on surgical defect
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Meniscus Injury
Clinical Application Research of Combined Therapy in ERAS for Accelerated Orthopedic Rehabilitation
The double-blind method is adopted.Case selection Patients who underwent meniscus repair surgery under knee arthroscopy at Li Huili Hospital Affiliated to Ningbo University, the 906th Hospital of the People's Liberation Army…
- Trial name
- NCT07273032
- Testing
- Blank control group, Henggu Bone Injury Healing Agent Intervention Group, Lower limb rehabilitation training system intervention group
- Volunteers
- 120 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury)
Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Clinicians are routinely required to make decisions about fall risk among lower limb prosthesis users. For these decisions, clinicians should use valid, reliable, quantitative, and multidimensional measures of balance test for…
- Trial name
- NCT05095584
- Testing
- 3 meter backward walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tezel Yıldırım Şahan
Anterior Cruciate Ligament Rupture
Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:
A randomized, single-blind, single-center study measuring the effects of adductor canal block combined with IPACK infiltration compared to adductor canal block alone on post-operative pain and opioid consumption in patients…
- Trial name
- NCT05286307
- Testing
- IPACK block
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
The goal of this randomized clinical trial is to evaluate the effects of vibration on factors related to the risks of post-traumatic knee osteoarthritis and secondary anterior cruciate ligament (ACL) injury in individuals who…
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Trial name
- NCT04875052
- Testing
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- University of North Carolina, Chapel Hill
Lower Extremity Injuries
Prediction of Lower Extremity Injuries Using Lower Limb-worn Inertial Measurement Units
This study analyses questionnaires and inertial sensor data from 108 sports science students regarding previous lower extremity injuries, sports activity, and preventive measures, combined with the prospective development of an…
- Trial name
- PredKnee (NCT07289828)
- Testing
- IMU Data collection, Questionnaire
- Where
- Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Fracture of Calcaneus, Pilon or Tibial Plateau
Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
This project is designed as a prospective, randomized, comparative study evaluating the use of a negative pressure vacuum device in treating soft tissue injuries and the surgical incision following open reduction and internal…
- Trial name
- VAC-ST (NCT00582998)
- Testing
- Standard Wound Dressing, Vacuum Assisted Closure Device
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Injury
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT03209531
- Testing
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Episodic Patellar Dislocation
Medial Patellofemoral Ligament Reconstruction With or Without Lateral Retinaculum Release
The investigators hypothesis is lateral retinaculum release has no effect on treatment of Patellar Recurrent Dislocation with Medial Patellofemoral Ligament (MPFL) reconstruction.
- Trial name
- NCT01719666
- Testing
- MPFL reconstruction and lateral retinaculum release, conventional surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Hospices Civils de Lyon
Articular Cartilage Injury
Evaluation of an Acellular Osteochondral Graft for Cartilage LEsions Pilot Trial
The Kensey Nash Corp. Cartilage Repair Device is a bioresorbable scaffold designed to promote repair of knee cartilage and subchondral bone.
- Trial name
- EAGLE Pilot (NCT01183637)
- Testing
- Kensey Nash Corp. Cartilage Repair Device, Microfracture
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Kensey Nash Corporation
ACL Tear, ACL Sprain
Knee vs. Ankle Training on Knee Mechanics After ACLR
This study will be conducted to investigate if there is any difference between starting rehabilitation program after ACL reconstruction with knee joint training followed by ankle joint training and starting it with ankle joint…
- Conditions
- ACL Tear, ACL Sprain, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries
- Trial name
- NCT05241795
- Testing
- Knee then Ankle rehabilitation protocol, Ankle then Knee rehabilitation protocol
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- October 6 University
ACL Injury, Muscle Weakness
Nordic Hamstring Exercise After ACL Reconstruction Reconstruction
Anterior cruciate ligament (ACL) injuries constitute a significant portion of major knee joint injuries sustained by young, active individuals, and significantly increase risk for long-term disability.
- Conditions
- ACL Injury, Muscle Weakness, Neuromuscular Manifestations
- Trial name
- NCT05738200
- Testing
- Nordic Hamstring Exercise
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Toledo
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Achilles Allograft With or Without InternalBrace for ACL Revision Surgery
This study evaluated outcomes after revision anterior cruciate ligament reconstruction using Achilles tendon allografts with a calcaneal bone block, with or without additional InternalBrace augmentation.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Graft Failure, Knee Instability
- Trial name
- ACL-AlloRev (NCT07564336)
- Testing
- Revision ACL Reconstruction With Achilles Tendon Allograft and InternalBrace Augmentation, Revision ACL Reconstruction With Achilles Tendon Allograft Without InternalBrace Augmentation
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz
Meniscal Degeneration, Osteoarthritis of Knee
Evaluation of Clinical and Radiographic Outcomes of Meniscal Lesion Treatment Using Collagen Scaffolds (CMI)
Meniscal lesions represent the most frequently encountered joint pathology in the adult population and can cause pain symptoms, mechanical blockages, and recurrent effusions.
- Conditions
- Meniscal Degeneration, Osteoarthritis of Knee, Meniscus Injury
- Trial name
- SUPER CMI (NCT06597357)
- Testing
- Arthroscopy & saline irrigation alone
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injuries
Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction
To evaluate the effect of graded exposure and mindfulness meditation after ACLR, the investigators will determine the effect of graded exposure and mindfulness meditation to 1) decrease self-reported injury-related fear and…
- Trial name
- NCT05949177
- Testing
- Graded Exposure and Mindfulness Meditation, Waitlist Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Knee Injuries
New MRI Measurement of Patellar Height in Knee Extension - IES-EV Control Study
The measurement of the patellar height is essential to decide and quantify the surgical correction to be made. The classic index is that of Cato and Deschamps.
- Trial name
- NCT05659316
- Testing
- MRI imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Anterior Cruciate Ligament Rupture
Blood Flow Restriction Following ACL Reconstruction
The main objective is to determine the impact of Blood Flow Restriction (BFR) therapy, in comparison to a standard rehabilitation protocol, on preventing atrophy, improving quadriceps strength and improving functional outcomes of…
- Trial name
- BFR (NCT03758755)
- Testing
- Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Inova Health Care Services
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