Clinical trials: Injury Brain
Rhabdomyolysis, Myopathy
Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients
1. Analyze the various causes of breakdown of muscle fibers in hospitalized patients. 2. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).
- Conditions
- Rhabdomyolysis, Myopathy, Acute Renal Failure, Neuroleptic Malignant Syndrome
- Trial name
- NCT01022450
- Where
- Taiwan
- Volunteers
- 2,500 people
- Sponsor
- National Taiwan University Hospital
Stroke, Ischemic, Inflammation
MR Evidence of Cardiac Inflammation Post-Stroke
The present study is an investigator initiated, single-centre, prospective, proof-of-concept cohort study aiming to enroll 44 patients with acute middle cerebral artery (MCA) ischemic stroke, involving the right (n=22) and left…
- Conditions
- Stroke, Ischemic, Inflammation, Myocardial Injury
- Trial name
- MIRACLE (NCT05714618)
- Testing
- Gadolinium-enhanced cardiac MRI, B Natriuretic Peptide, Systemic inflammatory markers
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Luciano A. Sposato
Moderate Traumatic Brain Injury (TBI)
Light Therapy for Moderate Traumatic Brain Injury
The purpose of this research study is to find out if a specialized helmet that provides low levels of near infrared light, also known as low-level light therapy (LLLT) has any effect on the recovery of people who have recently…
- Trial name
- LLLT for TBI (NCT02233413)
- Testing
- Active LLLT helmet application, Non-active LLLT helmet application
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Massachusetts General Hospital
Traumatic Brain Injury
MENTOR Wellness Program
This randomized trial aims to determine the effectiveness a virtual wellness intervention program in individuals with traumatic brain injury (TBI).
- Trial name
- NCT06148324
- Testing
- MENTOR Program
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- NYU Langone Health
Spinal Cord Injuries
Patient Self-managed BCI-FES
This study aims to assess the feasibility of therapist-caregiver-patient training to use BCI and FES technology with a view to the inexpensive equipment eventually being used for home use by tetraplegic patients as a continuing…
- Trial name
- NCT03257982
- Testing
- BCI-FES hand therapy
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Traumatic Brain Injury
Evaluation of VA's Traumatic Brain Injury (TBI) Clinical Reminder and Comprehensive TBI Evaluation (CTBIE)
The purpose of the proposed study is to determine the clinical validity and reliability of the VA's Traumatic Brain Injury (TBI) Clinical Reminder Screen and the Comprehensive TBI Evaluation used to screen for mild traumatic…
- Trial name
- TBI (NCT00852527)
- Where
- 3 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Spasticity, Stroke
Efficacy and Cost-effectiveness of Spasticity Treatment With Multifocal TENS
Spasticity is a common consequence of injury to the central nervous system and can be a major problem in motor function and everyday activities.
- Conditions
- Spasticity, Stroke, Cerebral Palsy
- Trial name
- NCT02261142
- Testing
- Multifocal TENS garment (Mollii®)
- Volunteers
- 31 people
- Sponsor
- Linkoeping University
Cerebral Palsy
The Relationship Between Education Status and Care Burden of Mothers of Individuals With Cerebral Palsy
This study, examines how maternal education affects caregiving burdens for children with cerebral palsy. Cerebral palsy requires long-term, intensive care, often leading to significant physical, emotional, and financial strain on…
- Trial name
- NCT06635070
- Volunteers
- 120 people
- Sponsor
- Muş Alparslan University
Traumatic Brain Injury, Cerebral Palsy
Walking Dynamic Among Children With Brain Damge
The goal of the present study was to look at the effect of changing walking parameters on the dynamic walking characteristics among children post severe traumatic brain injury, children with cerebral palsy and typically developed…
- Trial name
- NCT02839369
- Testing
- walking under varies conditions
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Traumatic Brain Injury (TBI); Concussion, Initial Encounter
Wearable Device-Based Analysis of the Relationship Between Sleep Patterns and Clinical Prognosis in Patients With Traumatic Brain Injury
In patients with traumatic brain injury, post-traumatic sleep patterns have the potential to impact clinical prognosis. While some progress has been made in the study of sleep and prognosis in patients with traumatic brain…
- Trial name
- NCT06790979
- Where
- China
- Volunteers
- 50 people
- Sponsor
- General Hospital of Ningxia Medical University
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Traumatic Brain Injury, Subarachnoid Hemorrhage
NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured Patients
This is an observational study in neurocritical care units at University of California San Francisco Medical Center (UCSFMC), Zuckerberg San Francisco General Hospital (ZSFGH), UC Davis, and Emory University.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Liver Failure
- Trial name
- NOVEL ICP (NCT04548596)
- Testing
- Transcranial Doppler
- Where
- 3 sites in United States
- Volunteers
- 162 people
- Sponsor
- Emory University
Concussion, Mild
Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion
The purpose of this study is to identify changes in salivary micro ribonucleic acid (miRNA) levels that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
- Trial name
- NCT04582682
- Where
- 5 sites in United States
- Volunteers
- 750 people
- Sponsor
- Milton S. Hershey Medical Center
Vegetative State, Minimally Conscious State
Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- NCT02626403
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- University of Liege
Cerebral Palsy, Scoliosis
Prospective Study of Cerebral Palsy Scoliosis
This is a prospective, multi-centre study that will be looking at two groups of males and females over the course of their operative treatment for cerebral palsy (CP) scoliosis and the years following that treatment.
- Trial name
- NCT00958542
- Testing
- Surgical fusion
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of British Columbia
Cerebral Palsy, Hemiparesis
Whole Body Vibration Versus Functional Strength Training On Balance In Children With Hemiparetic Cerebral Palsy
The study will be directed to compare which of whole body vibration (WBV) training and Functional strength training (FST) has better effect on balance in children with hemiparesis
- Trial name
- NCT05936554
- Testing
- whole body vibration, Functional strength training
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amany Ibrahim AbdElhamed Sabra
Brain Death, Anoxic Brain Injury
Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination
Current standard of care prior to determination of brain death in subjects with suspected anoxic brain injury is to exclude complicating medical conditions that may confound clinical assessment (such as severe electrolyte, acid…
- Conditions
- Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication
- Trial name
- NCT03743805
- Testing
- Flumazenil, Naloxone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Brain Injuries
The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
The aim of this study is to characterize the microbiome of patients undergoing post-acute residential neurorehabilitation compared to community controls and to determine if a dietary fiber, Inulin, can create a shift in the…
- Trial name
- NCT06607523
- Testing
- Inulin
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Brain Injury, Aggression
Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study
The purpose of this study is to study the effect of amantadine on irritability and aggression caused by traumatic brain injury.
- Trial name
- NCT00779324
- Testing
- Amantadine Hydrochloride
- Where
- 6 sites in United States
- Volunteers
- 168 people
- Sponsor
- Wake Forest University Health Sciences
Intraventricular Hemorrhage of Prematurity
Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants
The purpose of this randomized and placebo-controlled EpoRepair trial is to evaluate the effect of intravenously administered recombinant human erythropoietin (Epo) as compared to placebo in preterm infants with brain damage on…
- Trial name
- EpoRepair (NCT02076373)
- Testing
- recombinant human Erythropoietin
- Where
- 8 sites in Austria, Switzerland
- Volunteers
- 120 people
- Sponsor
- University of Zurich