Clinical trials: Injury Leg
Rupture of Anterior Cruciate Ligament
Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears
Anterior cruciate ligament (ACL) tears are among the most frequent traumatic knee injuries that occur in physically active individuals.
- Trial name
- NCT02420353
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Knee Injury, Knee Osteoarthritis
Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)
Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate…
- Trial name
- NCT01382173
- Where
- Sweden
- Volunteers
- 192 people
- Sponsor
- Lund University
Venus Leg Ulcer (VLU), VLU
Borate-based Bioactive Glass Fiber Matrix (BBGFM) in the Treatment of Venus Leg Ulcers (VLU)
The goal of this clinical trial is to learn if Borate-based Bioactive Glass Fiber Matrix (BBGFM) can help heal Venous Leg Ulcers (VLU) that have not closed with standard treatment. The main question it aims to answer is: 1.
- Conditions
- Venus Leg Ulcer (VLU), VLU, Venus Leg Ulcer, Venus Ulcer
- Trial name
- NCT07647705
- Testing
- Borate Based Bioactive Glass Fiber Matrix (BBGFM)
- Volunteers
- 110 people
- Sponsor
- ETS Wound Care, LLC
Stroke, Ankle Injuries
A Powered Ankle Foot Rehabilitation Orthosis
Ankle rehabilitation training becomes a tough question for the patients with ankle joint injuries especially with the hemiplegia after stroke.
- Trial name
- NCT01942772
- Testing
- Ankle-Foot Orthosis
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Technology
Proximal Femoral Fractures
Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures
The study aims to determine if antibiotic-loaded cement reduces post-surgery infection rates compared to non-antibiotic cement. The trial involves 450 elderly patients with specific hip fractures, assessing infection incidence…
- Trial name
- NCT06200402
- Testing
- Antibiotic loaded
- Where
- Italy
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Intertrochanteric Fractures, Internal Fixation Failure
Controlling Nutritional Status as a Superior Predictor of Fixation Failure in Intertrochanteric Fractures: Development and Validation of a Multicentre Nomogram
A multicentre retrospective cohort study was conducted within the Department of Orthopaedics at the First Affiliated Hospital of Fujian Medical University.
- Conditions
- Intertrochanteric Fractures, Internal Fixation Failure, CONUT Score, Nomogram Model
- Trial name
- NCT07159945
- Where
- China
- Volunteers
- 1,296 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Femoral Neck Fractures
Quantitative Analysis of Global Proteome in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
RATIONALE: Collecting and storing bone samples from patients with osteoporotic and nonosteoporotic fracture to quantitatively analyze the differentially expressed proteins to further explain the relationship between bone iron…
- Trial name
- NCT03428672
- Testing
- total hip arthroplasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Foreign-Body Reaction, Granulomatous Disease
Prospective Stage-Stratified Histopathologic Study and Proposed Disease-Evolution Model of Gluteal Permanent Synthetic Filler Complications
This prospective biospecimen cohort will collect and analyze tissue from adults undergoing clinically indicated surgery for gluteal permanent synthetic filler disease.
- Conditions
- Foreign-Body Reaction, Granulomatous Disease, Soft Tissue Necrosis Lower Limb, Gluteal Permanent Synthetic Filler Disease
- Trial name
- NCT07808970
- Testing
- Standardized Tissue Sampling During Clinically Indicated Surgery, Blinded Histopathologic Scoring
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Research Inc
Healthy, Osteopenia
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-preFX (NCT06567054)
- Testing
- Measurements with the POROUS R3C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine, DXA-based Vertebral Fracture Assessment (VFA)
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Hypotension, Hip Fractures
Acute Hip Fracture and Spinal Anaesthesia Injection Time
The systemic effects of spinal anesthesia is not fully known. Our aim of this study is to assess whether there is a difference in hemodynamic effects if the spinal dose is given fast (15s) or slow (90s) in elderly patients with…
- Conditions
- Hypotension, Hip Fractures, Anesthesia
- Trial name
- NCT05564741
- Testing
- Norepinephrine 1 MG/ML
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Sahlgrenska University Hospital
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
Knee Injuries and Disorders, Shoulder Disease
C Scope Visualization System Prospective Study
Evaluation of the performance and safety of the C Scope Visualization System
- Conditions
- Knee Injuries and Disorders, Shoulder Disease, Shoulder Injuries
- Trial name
- NCT05153863
- Testing
- C Scope Visualization System
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- CIT Ortho
Knee Injuries, Shoulder Injuries
Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery
The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative…
- Conditions
- Knee Injuries, Shoulder Injuries, Pain, Postoperative
- Trial name
- NCT04109638
- Testing
- Endonovo SofPulse
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Stanford University
Distal Femur Fracture
Far Cortical Locking Versus Standard Constructs for Distal Femur Fractures
To determine if Far Cortical Locking screws increase fracture healing rates at 3 months in Closed Distal Femur Fractures in adults when compared to Standard screw constructs.
- Trial name
- FCL (NCT01766648)
- Testing
- Far Cortical locking screw fixation, Standard screw fixation
- Where
- Canada
- Volunteers
- 167 people
- Sponsor
- University of British Columbia
Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
Use of Weightbearing Radiographs to Determine Treatment of bi- and Trimalleolar Ankle Fractures
The aim of this study is to evaluate the outcomes after non-operative treatment of weightbearing stable bi-and trimalleolar ankle fractures.
- Trial name
- NCT05765929
- Testing
- Non-operative treatment
- Where
- Norway
- Volunteers
- 29 people
- Sponsor
- Ostfold Hospital Trust
Femoral Fractures
Evaluation of the Effects of Less Invasive Stabilization System (LISS) Plating Techniques in Distal Femoral Fractures
The purpose of this study is to determine whether the rate of fracture healing and fracture union, repaired with the LISS device, will be as good as or better than the usual fracture fixation systems.
- Trial name
- NCT00552331
- Testing
- Plates to treat fractures of the distal femur, LISS
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Anterior Cruciate Ligament Injuries, ACL
Blood Flow Restriction Following ACLR
The purpose of this study is to evaluate the the ability of BFR to reduce muscle loss and improve strength after ACL reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, ACL, Physical Therapy
- Trial name
- NCT04086030
- Testing
- Blood Flow Restriction Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Total Knee Replacement, Arthroplasty
The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty
Short and long term outcomes of total knee arthroplasty patients surgically exposed with patellar eversion are compared to those patients exposed by laterally retracting the patella.
- Conditions
- Total Knee Replacement, Arthroplasty, Patella
- Trial name
- NCT01777009
- Testing
- Primary Total Knee Replacement Surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwell Health
Rupture of Anterior Cruciate Ligament, Anterolateral Ligament Reconstruction
Reconstruction of the Anterolateral Ligament (ALL) With Revision Anterior Cruciate Ligament (ACL) Surgery
Patients with combined Anterolateral ligament (ALL) reconstruction- Anterior cruciate ligament (ACL) revision will have a better rotational knee stability and therefore better patient reported outcome measure (PROM) scores…
- Trial name
- NCT02680821
- Testing
- ALL reconstruction (Anterolateral ligament), ACL revision (Anterior cruciate ligament )
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Aarhus University Hospital