Clinical trials: Injury Prevention
Epicondylitis, Tendonitis Elbow
Assessment of the Safety and Performance of an Elbow Brace in the Prevention of Injuries During Sports Practice
Decathlon has developed the Elbow soft300 which is a medical device that must be positioned around the elbow to keep a physical activity on a regular basis in case of chronic epicondylitis, pain associated with tendonitis or…
- Conditions
- Epicondylitis, Tendonitis Elbow, Elbow Injury
- Trial name
- NCT05552235
- Testing
- Elbow SOFT 300, Control group
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Decathlon SE
Cardiac Surgery Associated - Acute Kidney Injury, AKI - Acute Kidney Injury
Safety & Efficacy of RenalGuard® Therapy in the Prevention of Cardiac Surgery Associated Acute Kidney Injury
The goal of this clinical trial is to assess the effect of RenalGuard Therapy in reducing the rates of Acute Kidney Injury (AKI) within 72 hours after cardiac surgery in patients at risk of developing Cardiac Surgery Associated…
- Trial name
- SAFEGUARD (NCT07123935)
- Testing
- RenalGuard® Therapy, Standard of Care (SOC)
- Where
- 2 sites in Malaysia
- Volunteers
- 300 people
- Sponsor
- CardioRenal Systems, Inc.
Injuries
Safety Skills Training: Parents of School-Aged Children
Injuries are the leading cause of death and disability in children in America. Most injuries can be prevented when parents implement effective child safety practices.
- Trial name
- SAS_2 (NCT02329340)
- Testing
- Am Academy of Pediatrics print materials, Family safety 1-2-3
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Contrast-induced Acute Kidney Injury
A Study to Explore the Efficacy of Alprostadil Liposomes Injection in the Prevention of CI-AKI
This is a multicenter, randomized, open-label phase II clinical trial to evaluate alprostadil liposomal injection in the prevention of contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention.
- Trial name
- NCT05475717
- Testing
- Alprostadil liposome injection
- Where
- China
- Volunteers
- 132 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Ototoxicity
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
The primary objective of this study is to determine the safety and efficacy of SPI-1005 treatment in CF patients with active pulmonary exacerbation that are receiving an IV course of tobramycin, determined by comparing hearing…
- Trial name
- NCT02819856
- Testing
- SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Wound Contamination, Colorectal Surgery
Cleancision IntRaoperative Contamination prEvention Study
This study entitled, An Evaluation of the Safety and Efficacy of the CleanCision Wound Retraction and Protection System in Protecting Surgical Incisions from Intraoperative Contamination When Used during Colorectal Surgery, is…
- Trial name
- CIRCE (NCT02413879)
- Testing
- CleanCision
- Where
- 7 sites in United States
- Volunteers
- 108 people
- Sponsor
- Prescient Surgical
Ischemia-Reperfusion Injury, Lung Transplantation
Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation
The objective of this clinical study was to evaluate whether CXCL8 (CXC ligand 8 [formerly interleukin (IL)-8]) inhibition with repertaxin leads to reduced severity of primary graft dysfunction, as the result of improved…
- Trial name
- NCT00224406
- Testing
- Repertaxin
- Where
- 6 sites in United States, Canada
- Volunteers
- 114 people
- Sponsor
- Dompé Farmaceutici S.p.A
Chronic Knee Pain, Chronic Instability of Knee Joint
Assessment of the Safety and Performance of a Compression Knee Support in the Prevention of Injuries During Sports Practice
Decathlon has developed kneeSOFT100 product which is medical device designed to reduce pain and joint instability during sport practice.
- Trial name
- NCT04601168
- Testing
- kneeSOFT100
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- Decathlon SE
Athletes With Previous Lateral Ankle Sprain(s)
The Spraino Pilot Trial
This pilot study will establish the preliminary effect and safety of using Spraino® to prevent lateral ankle sprains amongst athletes competing in indoor sports at sub-elite level, with a one-year follow-up.
- Trial name
- NCT03311490
- Testing
- Spraino
- Where
- 2 sites in Denmark
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Spraino
Needle Stick
Simulated Clinical Use Testing on the DropSafe Safety Pen Needle
A simulated clinical use testing on the DropSafe safety pen needle
- Trial name
- NCT03803488
- Testing
- DropSafe safety pen needle
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Wounds
Outcome Assessment in Patients Treated With Hyperbaric Oxygen Using OxyVu Tissue Oxygenation Monitoring System
The objective is to define patient eligibility for hyperbaric oxygen therapy and to evaluate wound healing progression using a new hyperspectral imaging technology.
- Trial name
- HBOT (NCT00768027)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- HyperMed
Human Immunodeficiency Virus (HIV)
Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r)
The primary purpose of this study is to assess the rate of early discontinuation from randomized Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) for any reason other than confirmation of the negative HIV…
- Trial name
- PEPDar (NCT01516970)
- Testing
- Darunavir/Ritonavir (DRV/r), Lopinavir in fixed combination with Ritonavir, Zidovudine
- Where
- 17 sites in Germany
- Volunteers
- 312 people
- Sponsor
- Janssen-Cilag G.m.b.H
Surgical Site Infection, Colon Surgery
D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), compared to a SoC treated…
- Conditions
- Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
- Trial name
- NCT04233424
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 62 sites in United States, Bulgaria and 8 more
- Volunteers
- 977 people
- Sponsor
- PolyPid Ltd.
Radiation Dermatitis
StrataXRT Versus Aquaphor for the Prevention and Management of Radiation Dermatitis
The aim of this study is to assess the efficacy and safety of StrataXRT® in comparison to standard of care (defined using the Common Terminology Criteria for Adverse Events [CTCAE], version 5.0) by assessing the severity of…
- Trial name
- NCT05553392
- Testing
- StrataXRT, Aquaphor
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stratpharma AG
Needle Stick
Simulated Clinical Use Testing On Safety Lancets (Test B)
A simulated clinical use testing on the HTL-Strefa's safety lancets
- Trial name
- NCT03811444
- Testing
- Haemolance Plus safety lancet, Prolance safety lancet, MediSafe Solo safety lancet
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Tetanus
A Phase 4 Study to Evaluate the Effectiveness and Safety of Siltartoxatug Injection for Tetanus Prophylaxis Following Injury
Study sites were selected from hospitals across diverse regions of China. Approximately 6,000 participants who require passive immunization against tetanus due to various injuries (including those with severe wounds or heavily…
- Trial name
- NCT07347938
- Testing
- Siltartoxatug Injection, HTIG/TAT/F(ab')₂
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Zhuhai Trinomab Pharmaceutical Co., Ltd.
Acute Kidney Injury, Intensive Care
The Cost-effectiveness of Artificial Intelligence Acute Kidney Injury Prediction Auxiliary Software (Acura AKI)
"Huede" AI Aided AKI Prediction Software, Acura AKI, uses machine learning algorithms to predict the risk of AKI within the next 24 hours and provide a ranking of feature importance.
- Conditions
- Acute Kidney Injury, Intensive Care, Renal Replacement Therapy
- Trial name
- NCT06685367
- Testing
- Acura AKI
- Where
- Taiwan
- Volunteers
- 3,600 people
- Sponsor
- Huede Healthtech Co., Ltd.
Cardiac Surgery, Coronary Artery Bypass
An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery
This study investigates the effect of two dose-levels of AP214 on the prevention of (acute) kidney injury after cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass, Aortic Aneurysm, Valve Surgery
- Trial name
- NCT01256372
- Testing
- AP214
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Action Pharma A/S
Health Adult Subjects, Pressure Injury Prevention
A Trial to Investigate the New Caulis Pro® Low Air Loss (LAL) System
Investigation of biomechanical and physiological functions of laying on a new mattress in healthy volunteers.
- Trial name
- NCT07213739
- Testing
- CLP and pulsation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arjo AB
Liver Diseases
YSPSL for Prevention of Delayed Graft Function in Cadaveric Liver Transplantation
The study is designed to assess the feasibility of evaluating YSPSL for the amelioration of ischemia reperfusion injury following liver transplantation by administering YSPSL into the liver graft directly ex vivo via the portal…
- Trial name
- NCT00450398
- Testing
- YSPSL
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Y's Therapeutics, Inc.