Clinical trials: Injury Traumatic
Anxiety, Depression Disorder
Effects of Mindfulness and Self-regulation Training on Anxiety, Depression, PTSD, and Leadership
The goal of this study is to measure the effects of Mindfulness-based Mind Fitness Training (MMFT) on anxiety, depression, post-traumatic stress disorder, sleep quality, and leadership.
- Conditions
- Anxiety, Depression Disorder, PTSD - Post Traumatic Stress Disorder
- Trial name
- NCT07084233
- Testing
- Mindfulness based, trauma informed, self-regulation skills training
- Where
- Ukraine
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Subdural Hematoma
A Prospective Randomized Study Evaluating the Recurrence Rate of Chronic Subdural Hematoma After Placing a Subperiosteal Drainage Compared to a Subdural Drainage
The aim of our study is to investigate in randomized controlled fashion whether the recurrence and complication rate, after insertion of subperiosteal drainage in the treatment of chronic subdural haematoma, is higher compared to…
- Trial name
- NCT01869855
- Testing
- Subdural Drainage, Subperiosteal Drainage
- Where
- 2 sites in Switzerland
- Volunteers
- 220 people
- Sponsor
- Kantonsspital Aarau
Traumatic Brain Injury
Efficacy of Lung and Inferior Vena Cava Sonography for Fluid Optimization
Traumatic brain injury (TBI) is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed, management strategies must focus on preventing secondary injury by avoiding hypotension and…
- Trial name
- NCT05400343
- Testing
- Standard care (control group), US-guided fluid management (active group), Standard ICU Care
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Traumatic Chronic Encephalopathy
Cerebral and Cognitive Impact of Professional Soccer Practice
The objective of this study is to evaluate, using MRI, the microstructural consequences and the onset of any cognitive impairment in professional soccer players at the end of their career, who have experienced repeated minor head…
- Trial name
- TC-FOOT (NCT04903015)
- Testing
- MRI
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Traumatic Brain Injury
Approaches to Auditory Rehabilitation for Mild Traumatic Brain Injury
Many soldiers returning from their recent service in Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) were exposed to blasts during combat.
- Trial name
- mTBI (NCT00930774)
- Testing
- FM system, Auditory training
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- US Department of Veterans Affairs
Trauma Injury, Child, Only
Using mHealth to Improve Emotional Recovery After Pediatric Injury
Nearly 300,000 U.S. children experience injuries that require them to be hospitalized this year. These children, and their caregivers, are at high risk for emotional and behavioral problems, as well as poor quality of life.
- Conditions
- Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
- Trial name
- NCT04579198
- Testing
- Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
TBI
Neural and Behavioral Sequelae of Blast-Related Traumatic Brain Injury
Hypothesis 1: On fMRI scanning, frontoparietal activation during performance of executive function tasks of working memory, inhibitory control processes, and stimulus-response interference will exhibit greater signal intensity, a…
- Trial name
- NCT04012463
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Non PTSD, PTSD
Neurobiology of Sleep and Sleep Treatment Response in Returning Veterans
The overarching objectives of this study are: 1) To investigate the neurobiology of posttraumatic stress disorder (PTSD) during Rapid Eye Movement (REM) and Non-Rapid Eye Movement (NREM) sleep relative to wakefulness; 2) To…
- Trial name
- NOSSTIP (NCT01637584)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Post Traumatic Stress Disorder
Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder
Participation in post traumatic stress disorder observational study serves as a crucial contribution to advancing medical knowledge and refining the care provided to individuals facing similar health challenges.
- Trial name
- NCT06146049
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Post-Traumatic Stress Disorder, Acute Respiratory Failure
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
The RSI-LTO study collects long-term outcomes from the RSI trial (NCT05277896). One-third of adults who are intubated in the ED or ICU experience symptoms of posttraumatic stress disorder (PTSD).
- Trial name
- RSI-LTO (NCT06179485)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 1,756 people
- Sponsor
- Vanderbilt University Medical Center
Acute Spinal Cord Injury
Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury
Patients with traumatic spinal cord injury (tSCI) often suffer from spinal cord swelling inside the thecal sac, which contains the spinal cord and surrounding fluid, leading to increased pressure on the spinal cord tissue and…
- Trial name
- NCT06654804
- Testing
- Perflutren lipid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Interpersonal Trauma, Depression
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation.
- Conditions
- Interpersonal Trauma, Depression, PTSD, Anxiety
- Trial name
- BEAR-SI (NCT07346638)
- Testing
- BEAR-SI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Post-traumatic Stress Disorder
Ketamine and Prolonged Exposure in PTSD
This study aims at investigating the effectiveness of the drug, Ketamine, in combination with Prolonged Exposure (PE) therapy for people suffering from PTSD.
- Trial name
- NCT03960658
- Testing
- ketamine-enhanced prolonged exposure
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
PTSD
Exercise and Therapeutic Exposure
The proposed project seeks to demonstrate that a brief bout of aerobic exercise can improve a particular type of therapeutic learning among victimins of interpersonal violence with or without posttraumatic stress disorder (PTSD).
- Trial name
- NCT05177458
- Testing
- Experimental, Active Control
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Thomas Adams
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Spontaneous Abortion
Post-traumatic Stress Disorder in Spontaneous Abortion
The objective of this questionnaire-based study is to prospectively assess the prevalence of post-traumatic stress disorder (PTSD) symptoms in a population of women who have experienced a spontaneous miscarriage during the first…
- Trial name
- NCT07306676
- Testing
- Impact of Event Scale - Revised (IES-R) questionnaire, Posttraumatic Stress Disorder Checklist - Specific (PCL-S) questionnaire, Trauma Recovery Measure (TRM) questionnaire
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Normal Physiology, fMRI
The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans
Background: Two areas on the surface of the brain, the dorsolateral prefrontal cortex (DLPFC) and motor cortex (MC), play a key role during learning.
- Trial name
- NCT01260740
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Traumatic Brain Injury
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans
The primary purpose of this project is to determine the effect of morning bright light therapy (MBLT) on sleep in Veterans with traumatic brain injury (TBI).
- Trial name
- NCT03968874
- Testing
- Light box therapy, Negative Ion Generator
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Portland VA Medical Center
Intensive Care Pediatric
Experiences Reported by Siblings of Children Hospitalized in the PICU
The care for a child in pediatric intensive care is recognized as a traumatic experience for the patient and their entourage. The needs and feelings of parents are relatively well supported in the literature.
- Trial name
- SIBCARE (NCT06664333)
- Testing
- Semi-structured interviews
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder, Depression
Electroconvulsive Therapy for Traumatic Memories
This study will investigate whether ECT treatment can reduce the effect of traumatic memories if those memories are recalled immediately prior to the ECT sessions.
- Trial name
- NCT04027452
- Testing
- Traumatic memory reactivation, Neutral memory reactivation
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Centre for Addiction and Mental Health