Clinical trials: Inositol, open to volunteers
Polycystic Ovary Syndrome (PCOS)
Brown Adipose Tissue Modulation in Polycystic Ovary Syndrome Using Infrared Thermography
This study will investigate brown adipose tissue-related physiological responses in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07896642
- Testing
- inositol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Health and Technology University
Polycystic Ovary Syndrome (PCOS)
Myo-Inositol Alone Versus Myo-Inositol Plus Alpha-Lactalbumin in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting reproductive-aged women and is associated with menstrual irregularities, infertility, hyperandrogenism, obesity, and insulin resistance.
- Trial name
- MIALA-PCOS (NCT07629895)
- Testing
- Myo-inositol, Alpha-Lactalbumin
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Quaid-e-Azam Medical College
Osteoporosis Secondary, Breast Cancer Females
Vitamin k, D-chiro Inositol and α-lactalbumin in Bone Homeostasis
In women with breast cancer undergoing adjuvant hormone therapy, the marked tissue hypoestrogenism induced by therapy with aromatase inhibitors and/or tamoxifen ± GnRH analogues causes a significant acceleration in bone mass…
- Trial name
- Synostea (NCT07256769)
- Testing
- Group 1: calcium carbonate/cholecalciferol, Group 2: Synostea® (calcium carbonate/cholecalciferol/vitamin K/α-lactalbumin/ d-chiro-inositol)
- Where
- 2 sites in Italy
- Volunteers
- 134 people
- Sponsor
- Regina Elena Cancer Institute
Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated…
- Trial name
- AMulet (NCT07241221)
- Testing
- Myo-inositol and folic acid supplement, Folic acid supplement
- Where
- Singapore
- Volunteers
- 182 people
- Sponsor
- National University Hospital, Singapore
Polycystic Ovarian Syndrome (PCOS)
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
In polycystic ovary syndrome (PCOS), changes in physical appearance i.e. weight gain, hirsutism, menstrual disturbances and infertility result in reduced quality-of-life.
- Trial name
- NCT07459595
- Testing
- Myoinositol, Metformin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Tariq
Functional Hypogonadism
Use of D-Chiro-inositol in Male Functional Hypogonadism Associated With Sexual Dysfunction
A prospective, uncontrolled, non-pharmacological interventional study conducted on men with functional or borderline hypogonadism, aimed at evaluating, after 3 months of supplementation with D-Chiro-inositol, changes in hormonal…
- Trial name
- HERO_2025 (NCT07584772)
- Testing
- D-chiro-inositol
- Volunteers
- 35 people
- Sponsor
- Cardarelli Hospital
Polycystic Ovary Syndrome (PCOS)
Effect of Levocarnitine Plus Myoinositol Versus Myoinositol Alone on Hormonal and Insulin Resistance in PCOS Women
The goal of this clinical trial is to learn if combination of levocarnitine and myoinositol works better than myoinositol alone on insulin resistance and hormonal parameters in subfertile women with insulin resistant polycystic…
- Trial name
- NCT07266259
- Testing
- Myoinositol, Levo-Carnitine
- Where
- 2 sites in Bangladesh
- Volunteers
- 72 people
- Sponsor
- Mst.Sumyara Khatun
Poly Cystic Ovary Syndrome
Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients
This study evaluates the efficacy of alpha-lipoic acid combined with myo-inositol, with or without metformin, in improving menstrual regularity and ovulation in non-diabetic women with polycystic ovary syndrome (PCOS).
- Trial name
- ALA-MYO-PCOS (NCT07630779)
- Testing
- Myo-inositol, Folic Acid, Alpha Lipoic Acid
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Beni-Suef University
Mastalgia
Local Treatment of Breast Pain Based on the Daily Use of a Topical Gel
The trial aims to investigate the effect of a topical application of a medical device based on inositol in recovering breast pain
- Trial name
- NCT07257770
- Testing
- inositol
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
PCOS (Polycystic Ovary Syndrome), Insulin Resistance
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder frequently associated with obesity, insulin resistance (IR), and metabolic dysfunction.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)
- Trial name
- NCT07770711
- Testing
- Metformin, İnositol, Folic Acid
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dicle University
Pregnancy Related
Myo-inositol During Pregnancy to Prevent Gestational Diabetes
Myoinositol is an insulin-like compound that is present in both plant and animal cells. Humans synthesize it naturally, but it is also obtained in our diet.
- Trial name
- NCT06575868
- Testing
- Myo-inositol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tufts Medical Center
Polycystic Ovary Syndrome, Reproductive Medicine
Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome
The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded.
- Trial name
- MYOPK (NCT03059173)
- Testing
- Myo-Inositol + Levomefolic acid, Clomiphene Citrate
- Where
- France
- Volunteers
- 276 people
- Sponsor
- University Hospital, Lille
Myo-inositol, Post Varicocelectomy
Comparative Study of Post-Varicocelectomy Myo-inositol vs. Antioxidants vs. Surgery Alone in Infertile Men
The purpose of this open-label, 3-arm randomized controlled trial is to compare the clinical efficacy and safety of adding oral myo-inositol versus conventional oral antioxidants (vitamin C, L-carnitine, and zinc) versus surgery…
- Conditions
- Myo-inositol, Post Varicocelectomy, Infertile Men, Varicocele
- Trial name
- MYO-VAR (NCT07915388)
- Testing
- Experimental Arm Intervention: Myo-inositol, Conventional Antioxidants, Group C (Control)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Fayoum University Hospital
Polycystic Ovary Syndrome (PCOS)
Efficacy of Oral Contraceptive, Progesterone, and Inositol on Menstrual Regulation in PCOS
This cross-sectional study aims to compare the effectiveness of oral contraceptives, oral progesterone (didrogesterone), and inositol in regulating menstrual cycles among women diagnosed with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07242131
- Testing
- Combined Oral Contraceptive (Ethinylestradiol 0.03 mg + Drospirenone 3 mg), Inositol mid-level volume, Dydrogesterone Pill
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Thyroid Nodule
Myo-inositol and Selenium in Indeterminate Thyroid Nodules (TIR3a)
Thyroid nodules present a variable risk of malignancy depending on the cytological result obtained from the ultrasound-assisted thyroid fine needle aspiration biopsy.
- Trial name
- MYOSEL (NCT06736015)
- Testing
- Myo-Inositol 600 mg + Selenium 83 mcg
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Regina Elena Cancer Institute
Gestational Diabetes Mellitus (GDM)
Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus
This randomized controlled trial aims to compare the efficacy of Glucophage plus Myo-Inositol versus Glucophage alone in glycemic control among patients with gestational diabetes mellitus (GDM).
- Trial name
- NCT06840613
- Testing
- Myo-Inositol, Glucophage
- Volunteers
- 90 people
- Sponsor
- University of Health Sciences Lahore
Gestational Diabetes Mellitus (GDM)
The Impact of Myo-Inositol on Glycemic Control and Oxidative Stress in Gestational Diabetes Mellitus
The purpose of this clinical study is to investigate the potential effects of myo-inositol supplementation on changes in glycemic control parameters, oxidative stress, inflammatory biomarkers, psychometric markers, and body…
- Trial name
- NCT07685015
- Testing
- Myo-inositol 2 g + Folic acid 200 µg, Folic acid 200 µg, Insulin therapy
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Polycystic Ovary Syndrome
Effects of Oral Inositol Supplementation on Obstetrics Outcomes in PCOS Women
Polycystic ovarian syndrome (PCOS) is a heterogeneous, multifaceted and complex disorder characterized by insulin resistance (IR), hyperinsulinemia, and hyperandrogenism leading ovarian disfunction and infertility.
- Trial name
- IPOSI-1 (NCT03585738)
- Testing
- Inositol + Folic acid, Folic acid
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Male Infertility
Efficacy Study of a Food Supplement With Myo-inositol, N-Acetyl-Cystein, Zinc and Vitamins on Sperm DNA Fragmentation
In industrialised countries, it is estimated that about 15% of couples who wish to have a child are currently facing infertility problems, of which, in half of the cases, an anomaly in sperm quality or at least a factor of male…
- Trial name
- NCT04959864
- Testing
- Isitol®
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GYNOV
Uterine Fibroids, D-chiro-inositol
Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid
The study will evaluate the impact on uterine fibroids' volume of a combination of natural molecules including Epigallocatechin gallate, Vitamin D, D-chiro-inositol and Vitamin B6.
- Conditions
- Uterine Fibroids, D-chiro-inositol, Inositol, Epigallocatechin Gallate
- Trial name
- NCT05448365
- Testing
- Epigallocatechin gallate, Vitamin D, Vitamin B6, D-chiro-inositol
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Lo.Li.Pharma s.r.l