Clinical trials: Insemination
Virtual Reality, Anxiety
The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI)
This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction.
- Conditions
- Virtual Reality, Anxiety, Patient Satisfaction, Intrauterine Insemination (IUI)
- Trial name
- (IUI) (NCT06346730)
- Testing
- Virtual reality glasses to intervention group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Infertility, Insemination
Pozzi Forceps in Intrauterine Insemination
Many infertility and subfertility issues are treated nowadays with intrauterine inseminations. This is a minimally invasive technique that consists in placing sperm into a woman's uterus.
- Trial name
- NCT03435809
- Testing
- Intrauterine insemination
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
No Explained Sterility
Step Up Versus Step Down in Controlled Ovarian Stimulation
The aim of the study is to evaluate if the Step up protocol is equal or superior regarding efficacy and security than the step down protocol. In couple submitted two intrauterine insemination.
- Trial name
- NCT01376999
- Testing
- FSH-r (Follicule stimulate hormone)
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Embryo Transfer, Intrauterine Insemination (IUI)
Semi-quantitative Pregnancy Test to Monitor hCG Levels After Assisted Fertility Treatment
Given the potential of semi-quantitative pregnancy tests as part of assisted fertility care, the investigators would like to document the feasibility and acceptability of a semi-quantitative pregnancy test as an adjunct to or…
- Trial name
- NCT01919502
- Testing
- Semi-quantitative urine pregnancy test
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
HIV-1, Fertility
Intrauterine Insemination In HIV-Discordant Couples
This study aims to assess the feasibility of a novel standard of care technique for intrauterine insemination (IUI) in HIV-discordant couples in the United States.
- Conditions
- HIV-1, Fertility, Infertility
- Trial name
- ARTEMIS (NCT01173276)
- Testing
- Sperm Washing with Intrauterine Insemination (IUI)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Infertility
Sperm Motility and IUI Live Birth Rate
This prospective cohort study aims to establish a cut-off threshold for pre-washed total rapidly motile sperm count (TRMSC) based on WHO 2021 criteria to predict the live birth rate following intrauterine insemination (IUI).
- Trial name
- IUI (NCT06117995)
- Testing
- Assessment the pre-washed sperm motility before IUI
- Volunteers
- 536 people
- Sponsor
- Mỹ Đức Hospital
Ovarian Stimulation Preceding Intrauterine Insemination
Comparing Highly Purified hMG With Recombinant FSH + Recombinant LH in Women Undergoing Intrauterine Insemination.
The present study aims to elucidate if the FSH and LH activity contained in hMG preparations is comparable to the recombinant FSH and LH administration in a 1:1 ratio.
- Trial name
- NCT00820482
- Testing
- Menopur®, Ferring, rFSH (Gonal®,
- Where
- 2 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Pregnancy
Endometrial Injury Versus Luteal Phase Support in Intrauterine Insemination Cycles
The investigators will try to assess the effect of endometrial injury preceding the intrauterine insemination cycle on the pregnancy rates compared to cycles with luteal phase support and the control group.
- Trial name
- NCT02492451
- Testing
- Endometrial Injury, progesterone (Crinone® %8 vaginal progesterone gel)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Infertility, Intrauterine Insemination (IUI)
The Level of Infertility Distress and Fertility Readiness of Women
The infertility treatment process is a multidisciplinary teamwork involving different professional groups. Especially the Controlled Ovarian Hyperstimulation (COH) protocols applied during the infertility treatment process…
- Trial name
- NCT06659497
- Testing
- web-based patient education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duzce University
Infertility
A Pilot Study Analyzing Reproductive Results After IUI Using Vitrified Human Sperm
The aim of this study is to assess the evaluate the effectiveness of vitrified donor semen in intrauterine insemination treatments.
- Trial name
- BIOKIBANK (NCT06243913)
- Testing
- IUI with vitrified sperm from donor:
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Clínica EUGIN
Infertility
Use of a Calcium Channel Blocker to Prevent Premature Luteinizing Hormone Surges in Infertility Patients
Nimodipine (Nimotop® Bayer Pharmaceuticals Corporation), unlike other calcium channel blockers is fat soluble and therefore is able to cross the blood-brain barrier1.
- Trial name
- nimodipine (NCT01551368)
- Testing
- Nimodipine
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
Anti-Müllerian Hormone is Not Predictive of Pregnancy in Donor Insemination Cycles in Non-infertile Women
To evaluate if ovarian reserve (measured by means of anti-mullerian hormone -AMH- and antral follicle count -AFC-) can predict pregnancy in donor insemination cycles (dIUI) performed in non-infertile women.
- Trial name
- NCT03160872
- Testing
- Anti Mullerian Hormone Measurement
- Volunteers
- 143 people
- Sponsor
- Fundacion Dexeus
Reproductive Issues
The Efficacy and Safety of Female PRP Co-incubation With Sperm During (IUI) Cycles
The investigators hypothesize that infertility patients undergoing IUI who receive female autologous platelet-rich plasma (PRP) co-incubation with husband's sperm would have higher clinical pregnancy rate.
- Trial name
- NCT07615634
- Testing
- non-PRP group (control group), PRP group (intervention group)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Chinese University of Hong Kong
Unexplained Infertility
The Predictive Value of the Sperm Chromatin Dispersion Test, Halosperm®, Before and After Sperm Preparation for Clinical Pregnancy in Cases of Unexplained Infertility Treated With Intra-uterine Insemination (First Cycle) and Ovulation Induction With Clomiphene Citrate.
Recent research has revealed that subtle abnormalities can be found in sperm samples that seem to be normal with conventional analysis techniques.
- Trial name
- DNAFRAG (NCT02235103)
- Testing
- Sperm Chromatin Dispersion Test
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Ghent
Hysteroscopy, Pregnancy Rate
Hysteroscopic Metroplasty in Unexplained Infertile Women With Dysmorphic Uterus
The correlation between dysmorphic uterus and infertility still remains enigmatic. We aim to evaluate the reproductive outcomes of metroplasty via office hysteroscopy in unexplained infertile women with dysmorphic uterus with…
- Conditions
- Hysteroscopy, Pregnancy Rate, Abortion, Ectopic Pregnancy
- Trial name
- COH/IUI (NCT03579550)
- Testing
- office hysteroscopic metroplasty intervention arm
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Bulent Haydardedeoglu
Pregnancy, Live Birth
Folic Acid and Zinc Supplementation Trial (FAZST)
The overarching goal of this trial is to determine if an intervention comprising folic acid and zinc dietary supplementation improves semen quality and indirectly fertility outcomes (i.e., live birth rate) among couples trying to…
- Conditions
- Pregnancy, Live Birth, Spontaneous Abortion
- Trial name
- FAZST (NCT01857310)
- Testing
- 5 mg folic acid and 30 mg elemental zinc
- Where
- 4 sites in United States
- Volunteers
- 2,370 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Reproductive Issues
Factors Associated With Clinical Pregnancy Outcomes in Intrauterine Insemination (IUI) Cycles
Hypotheses: We hypothesize that variations in hormonal profiles (LH, estradiol, progesterone) during ovarian stimulation, follicular response, endometrial characteristics, and sperm quality parameters are significantly associated…
- Trial name
- NCT07344623
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Effect on Implantation and Pregnancy Rates
Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Seminal plasma insemination into the vaginal vault of patients undergoing IVF-ET increases uterine receptivity.
- Trial name
- NCT01809366
- Testing
- seminal plasma insemination
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
HIV Infections
The Impact and Cost-effectiveness of Safer Conception Strategies for HIV-discordant Couples (SAFER)
This is a prospective, non-randomized, open-label study to look at the uptake, adherence to, and impact of pre-exposure prophylaxis (PrEP), antiretroviral therapy (ART), semen washing, and vaginal insemination to prevent HIV…
- Trial name
- SAFER (NCT03049176)
- Testing
- PrEP (Truvada), Antiretrovirals, Semen washing
- Where
- Zimbabwe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Intrauterine Insemination
GnRH Agonist and Intrauterine Insemination
The aim of this study is to assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles.
- Trial name
- NCT00503217
- Testing
- Tryptorelin
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA