Clinical trials: Insomnia, Primary
Primary Insomnia
Safety and Efficacy of an Ambulatory Biofeedback Device for Primary Insomnia
The objective of this study is to determine the efficacy of a portable biofeedback device on improving sleep latency and other sleep variables such as nocturnal awake time and daytime functioning in persons with primary insomnia.
- Trial name
- NCT00415714
- Testing
- Portable Biofeedback
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Helicor
Primary Insomnia, Secondary Insomnia
An Efficacy Study of Compound LY2624803 in the Treatment of Patients With Chronic Insomnia
The purpose of this study is to compare an investigational drug (LY2624803) with placebo and with zolpidem in the treatment of outpatients with chronic insomnia.
- Trial name
- SLUMBER (NCT00784875)
- Testing
- LY2624803, zolpidem
- Where
- 49 sites in United States
- Volunteers
- 643 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Primary Hypersomnia
Neurophysiologic Correlates of Hypersomnia
The goal of this project is to examine the neurophysiology of hypersomnia during sleep and wakefulness, to identify biomarkers for excessive sleepiness in neuropsychiatric disorders, and pilot acoustical slow wave induction…
- Conditions
- Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy
- Trial name
- NCT01719315
- Testing
- Acoustical slow wave induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Primary Insomnia
Phase IIB 2-Period Crossover Polysomnography Study in Participants With Primary Insomnia (MK-4305-006)
A cross-over, polysomnography study to test the safety, tolerability and effectiveness of different doses of suvorexant (MK-4305) in the treatment of patients with primary insomnia.
- Trial name
- NCT00792298
- Testing
- Suvorexant
- Volunteers
- 254 people
- Sponsor
- Merck Sharp & Dohme LLC
Insomnia, Sleep Initiation and Maintenance Disorders
Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)
This study was conducted to investigate the efficacy of treatment with Org 50081 (Esmirtazapine) compared to placebo in elderly participants with chronic primary insomnia.
- Conditions
- Insomnia, Sleep Initiation and Maintenance Disorders, Mental Disorders, Dyssomnias
- Trial name
- NCT00561821
- Testing
- Esmirtazapine
- Volunteers
- 538 people
- Sponsor
- Merck Sharp & Dohme LLC
Primary Insomnia
Comparison of Efficacy of Behavioral Approaches for Treatment of Insomnia
This study compares the efficacy of four different types (Cognitive Behavior Therapy for Insomnia (CBT-I); Focus of Attention (FOA); Combined CBT-I and FOA; and Sleep Hygiene (control group) for the treatment of insomnia.
- Trial name
- CEBATI (NCT03461666)
- Testing
- Cognitive Behavior Therapy-Insomnia, Focus of Attention, Combined-CBT-I and FOA Group
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pacific Institute of Medical Sciences
Insomnia
A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.
The purpose of this study is to determine whether a handheld computer is superior to a self-help manual for the treatment of chronic primary insomnia.
- Trial name
- NCT00310284
- Testing
- Computerized delivery of cognitive-behavioral treatment of insomnia, Self-help manual to improve insomnia symptoms
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- PICS, Inc.
Primary Brain Tumor, Glioblastoma
CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial
This study seeks to investigate an evidence-based, manualized, behavioral health intervention, Cognitive Behavioral Therapy for Insomnia (CBT-I), in individuals with primary brain tumors (PBT) and insomnia.
- Conditions
- Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma
- Trial name
- CBT-I in PBT (NCT06439420)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Virginia Commonwealth University
Primary Insomnia, Chronic Insomnia
Chamomile for Chronic Primary Insomnia
The purpose of this study is to determine if an herb called chamomile can help to treat insomnia (difficulty in going to sleep or getting enough sleep) by increasing the amount of time that you sleep and/or improving the quality…
- Trial name
- NCT01286324
- Testing
- Chamomile High Grade Extract
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan
Primary Insomnia
Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients
To evaluate the clinical efficacy and safety of neuromodulation by transcranial direct current stimulation (tDCS) in the patients with primary chronic insomnia .
- Trial name
- NCT02832804
- Testing
- transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Seoul National University Hospital
Fatigue, Head and Neck Cancer
Insomnia in Patients Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer
RATIONALE: Learning about insomnia and quality of life in patients undergoing chemotherapy and radiation therapy for cancer may help doctors learn about the effects of treatment and plan the best treatment.
- Conditions
- Fatigue, Head and Neck Cancer, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders
- Trial name
- NCT00616590
- Testing
- medical chart review, questionnaire administration, fatigue assessment and management
- Where
- 3 sites in United States
- Sponsor
- Vanderbilt University
Insomnia
A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care
The overall objective of this study is to conduct a randomized effectiveness-implementation trial to test the non-inferiority of tele-Brief Behavioral Treatment for Insomnia vs.
- Trial name
- NCT05759065
- Testing
- Tele-Brief Behavioral Treatment for Insomnia, Tele-Cognitive-Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Primary Insomnia
MK0928 Study in Adult Patients With Primary Insomnia (0928-040)(COMPLETED)
A study to evaluate the efficacy, safety and tolerability of MK-0928 in Primary Insomnia.
- Trial name
- NCT00266344
- Testing
- MK0928, gaboxadol / Duration of Treatment 3 Weeks
- Volunteers
- 520 people
- Sponsor
- H. Lundbeck A/S
Primary Insomnia
A Study of Gaboxadol in Primary Insomnia
To evaluate the safety and tolerability of gaboxadol in primary insomnia.
- Trial name
- NCT00209963
- Testing
- Gaboxadol
- Volunteers
- 600 people
- Sponsor
- H. Lundbeck A/S
Primary Insomnia
Sleep Homeostasis in Primary Insomnia
About 10% of the population is believed to suffer from Primary Insomnia. It is also believed that people with chronic insomnia have a sleep system that is essentially out of alignment (we call this "homeostatic dysregulation").
- Trial name
- NCT00256503
- Testing
- Cognitive-Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Primary Insomnia
Adult Primary Insomnia Polysomnographic Study (0928-004)(COMPLETED)
The purpose of the study is to test the safety and effectiveness of the Investigational Drug on insomnia.
- Trial name
- NCT00094627
- Testing
- gaboxadol
- Volunteers
- 465 people
- Sponsor
- H. Lundbeck A/S
Insomnia Chronic, Migraine Disorders
Digital CBTI for Comorbid Insomnia in Chronic Migraine
The overall aims of the study are: Aim 1: Estimate effect sizes: To estimate the effects of dCBT-I on insomnia symptoms compared to a control group (sleep hygiene education) and estimate the relationship between changes in…
- Trial name
- NCT05244889
- Testing
- Digital CBT-I, Sleep Hygiene Education
- Where
- 2 sites in United Kingdom
- Volunteers
- 88 people
- Sponsor
- University of Strathclyde
Nonorganic Insomnia, Primary Insomnia
Better Nights, Better Days for Typically Developing Children
Up to 25% of children suffer from sleep problems categorized as "insomnia": difficulty settling, falling asleep, and staying asleep.
- Trial name
- BNBD (NCT02243501)
- Testing
- Intervention Group
- Where
- Canada
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Primary Insomnia
How do Sleeping Pills Affect Pain in the Brain?
If you are age 20-55 years old and have trouble falling or staying asleep, then please contact a UCSD research team to find out how a study drug affects these symptoms and how your brain works.
- Trial name
- NCT00414037
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Insomnia Disorder
Brief Behavioral Insomnia Treatment Study
The purpose of this study is to determine whether a brief, behavioral treatment for insomnia is effective in addressing social and occupational functioning and overall health among Veterans with insomnia disorder.
- Trial name
- BBTI (NCT02571452)
- Testing
- Brief Behavioral Treatment for Insomnia, Progressive Muscle Relaxation
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- VA Office of Research and Development