Clinical trials: Insufflation
Lung Function
Lung Function After Robot-assisted Radical Prostate Ectomy
The aim of our study is to investigate if the use of the AirSeal insufflation system impairs the lung function of patients less than a conventional system in patients undergoing robot-assisted laparoscopic radical prostatectomy…
- Trial name
- NCT02066246
- Testing
- AirSeal, Olympus UHI-3
- Where
- 2 sites in Germany
- Volunteers
- 192 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Apnea, Ventilation Therapy; Complications
THRIVE in Children at Different Flow Rates
This study investigates under controlled circumstances the concept of THRIVE to improve the ventilation and the carbon dioxide elimination, to prolong the apnoea time without deoxygenation and to improve safety of airway…
- Trial name
- NCT03812354
- Testing
- THRIVE 4L/kg/min, THRIVE 2L/kg/min
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Oxygen Deficiency, Desaturation of Blood
THRIVE Use in Pediatric Populations- Multi Site
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT04322994
- Testing
- Transnasal Humidified Rapid-Insufflation Ventilatory Echange
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Stanford University
Water Assisted Colonoscopy
Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training
This study will be a randomized trial comparing the use of only water or water and air insufflation during colonoscopy insertion by trainees.
- Trial name
- NCT04987645
- Testing
- Water-only infusion technique, Water infusion and air insufflation
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Airway Clearance, Mechanical Insufflation-exsufflation
Mechanical Insufflation-Exsufflation in Critically Ill Patients
Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases.
- Conditions
- Airway Clearance, Mechanical Insufflation-exsufflation, Mechanical Insufflation-exsufflation Session ( With Cough Assist), Delphi Study
- Trial name
- DELMI-E (NCT07420946)
- Testing
- Delphi Questionnaire
- Where
- 4 sites in Italy, Spain and 1 more
- Volunteers
- 30 people
- Sponsor
- Medipol University
Cholelithiasis
The Effect of Preoxygenation on Gastric Decompression in Laparoscopic Cholecystectomies
Aim: Gastric insufflation caused by mask ventilation during laparoscopic surgeries may affect the surgical field, lead to regurgitation of gastric contents, and consequently cause aspiration pneumonia.
- Trial name
- NCT07274488
- Testing
- Preoxygenation, Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Colonoscopy
Comparisons of SWI, WWI and CI in Potentially Difficult Colonoscopy.
Colonoscopy insertion is technically challenging, time-consuming, and painful, especially for the sigmoid. It is reported that the difficult colonoscopy score (DCS) >1 can predict the difficulty during colonoscopy.
- Trial name
- NCT03571061
- Testing
- whole colon water immersion and sigmoid water immersion
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Pain
CO2 Insufflation During Double Balloon Enteroscopy
Double-balloon enteroscopy (DBE) is a novel endoscopic procedure for visualising the entire small bowel. In any GI endoscopy procedure it is mandatory to insufflate gas into the bowel to secure good visualisation.
- Trial name
- NCT00464022
- Testing
- Carbon dioxide
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Rikshospitalet University Hospital
Laparoscopic Hysterectomy
Post Operative Pain After Laparoscopic Hysterectomy Using Airseal® Versus Standard Insufflation System
Airseal® is an insufflation management system for laparoscopic surgery which provides stable pneumoperitoneum, continuous smoke evacuation and valve-free access to the abdominal cavity.
- Trial name
- AIRSEAL (NCT03418402)
- Testing
- Airseal®, Standard insufflator
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Air Insufflation, Regurgitation
Risk of Gastric Insufflation Related to Facemask Ventilation Technique During Anaesthetic Induction, With or Without PEEP
Continuous positive pressure during anesthetic induction is today not routinely used partly a to the risk of gastric insufflation because of higher ventilatory pressures.
- Trial name
- NCT02238691
- Testing
- Mask ventilation with PEEP via a face mask device
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Neuromuscular Diseases
Home Use of Mechanical Insufflation/Exsufflation Devices in Neuromuscular Diseases
With this cross-sectional study of adult subjects with neuromuscular disease in the French-speaking part of Switzerland, we aim to explore MI-E adherence using self-report questionnaires and device data in order to identify the…
- Trial name
- NCT04729920
- Testing
- Mechanical insufflation/exsufflation device (MI-E)
- Where
- Switzerland
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Serrated Polyp
Serrated Polyp Detection Rate Between Carbon Dioxide and Air Insufflation
Sessile serrated adenomas are characterized by their flat shape and the presence of a yellow mucus cap overlying the lesion. These morphological features may account for their diagnostic difficulty during colonoscopy.
- Trial name
- NCT03623906
- Testing
- Carbon dioxide insufflation colonoscopy, Air insufflation colonoscopy
- Volunteers
- 1,280 people
- Sponsor
- The Catholic University of Korea
Children
The Laryngeal Mask Airway (LMA) Unique and the Air-Q Intubating Laryngeal Airway (ILA) in Pediatric Patients
The air-Q® intubating laryngeal airway (ILA) is an supraglottic device used for both airway maintenance during routine anesthesia and as a conduit for tracheal intubation for patients with a difficult airway.
- Trial name
- NCT01314248
- Testing
- each child will receive both the LMA and ILA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pediatric Sedation, Radiotherapy
Sevoflurane Insufflation vs Intravenous Sedation for Radiotherapy in Pediatric Patients
aim of this cross-over study is to compare sedation with insufflated sevoflurane and intravenous sedation for pediatric radiotherapy patients
- Conditions
- Pediatric Sedation, Radiotherapy, Inhalation Anesthesia
- Trial name
- NCT04483258
- Testing
- Sedation with sevoflurane insufflation, intravenous sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Decompensated Heartfailure, Cardio-renal Syndrom
Nasal High Flow at Acute Hart Failure
The pilot study aims to compare the results of using a new respirator (OPTIFLOW TM-High-Flow-Machine) with those from Standard-Oxygen-Therapy during the stabilization of patients who have been hospitalized due to acute heart…
- Trial name
- NCT02058810
- Testing
- Nasal high flow, Conventional nasal oxygen
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- University Hospital Regensburg
Hypothermia
Effects of Warmed, Humidified CO2 Insufflation on Body Core Temperature and Cytokine Response
The aim of this study is to assess if the conditioning of the insufflation carbon dioxide (CO2) allows for an additional benefit in terms of prevention of the heat loss, when compared with the usual prevention with a forced warm…
- Trial name
- NCT02586974
- Testing
- Humigard
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Anesthesia
Evaluation of Lung Atelectasis During Apneic Oxygenation Using THRIVE in Adults During Laryngeal Surgery.
Oxygenation with high-flow nasal cannula with 100% oxygen have now been evaluated in a number of studies and the data are convincing.
- Trial name
- A-THRIVE (NCT03458091)
- Testing
- THRIVE, Endotracheal intubation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska University Hospital
Colonic Disease
Evaluation of the Contribution of Low-pressure Intra-abdominal Insufflation for Laparoscopic Colic Resection
The laparoscopic surgery requires gas insufflation in the peritoneal cavity and the operator chooses the intraabdominal insufflation pressure. In general, during a conventional laparoscopy, this pressure is 12 to 15 mmHg.
- Trial name
- LoPreCol (NCT04112654)
- Testing
- Conventional pressure laparoscopy, Low pressure laparoscopy
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Institut Paoli-Calmettes
Extremely Low Birthweight Infant, Continuous Tracheal Gas Insufflation
Ventilation of the Extremely Premature Infants Optimized by Dead Space Washout
The Continuous Tracheal Gas Insufflation (CTGI) is a ventilation option of conventional mechanical ventilation that is used to reduce or even eliminate the dead space caused by respiratory prostheses.
- Conditions
- Extremely Low Birthweight Infant, Continuous Tracheal Gas Insufflation, Medical Device, Lung Protection
- Trial name
- Volem (NCT06334523)
- Testing
- Ventilation with Dead Space Washout via Continuous Tracheal Gas Insufflation (CTGI)
- Where
- 4 sites in France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Respiratory Failure Without Hypercapnia, Respiratory Failure With Hypercapnia
Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)
Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations.
- Conditions
- Respiratory Failure Without Hypercapnia, Respiratory Failure With Hypercapnia, Postoperative Respiratory Complication
- Trial name
- NCT06988111
- Testing
- BIPAP, Vapotherm
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Assiut University